Regranex Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Regranex cost savings if eligible

If you are eligible for the Regranex patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Regranex through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Regranex patient assistance program?

You could receive your Regranex without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Regranex patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Regranex.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Regranex patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Regranex medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Regranex coupon provider?

At NiceRx, we help eligible individuals access the Regranex patient assistance program. This means that we are not a Regranex coupon, a Regranex discount card, or a Regranex copay card provider. We do not offer any medication trial offers, or free Regranex samples.

Can NiceRx help me get Regranex cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Regranex medication, or if you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Regranex cost without insurance?

Regranex costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Regranex topical gel 0.01% will typically cost around $1,300 for 15 grams. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Regranex cost with insurance?

The copay of Regranex will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Regranex?

Regranex is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Smith & Nephew, Inc. Regranex gel is the only FDA-approved platelet-derived growth factor (PDGF) therapy for diabetic neuropathic ulcers.

Regranex is used for the treatment of lower extremity diabetic ulcers that extend into the subcutaneous tissue or beyond and have an adequate blood supply. Regranex is not a substitute for good ulcer care practices, but more so to be used alongside good ulcer wound care.

The efficacy of Regranex gel has not been established for the treatment of pressure ulcers and venous stasis ulcers. Regranex gel should not be used in wounds that are close by primary intention. Also, the effects of Regranex gel on exposed joints, tendons, ligaments, and bone have not been established in humans.

What doses of Regranex are available?

Regranex is available in gel form, in the following doses: 0.01%.

Regranex gel is for topical use, it is not for oral, ophthalmic or intravaginal use. The length of gel of Regranex you apply will depend upon the size of the ulcer area. Each square inch of ulcer surface will need 2/3 inch length of gel squeezed from a 15 g tube. The amount of gel to be applied should be recalculated at weekly or biweekly intervals depending on the rate of change in ulcer area.

To apply Regranex, the gel should be squeezed onto a clean measuring surface, e.g., wax paper. The gel is transferred from the clean surface using an application aid (cotton swab, tongue depressor) and spread over the cleaned ulcer area to give a thin layer.

Cover the application site with a saline moistened gauze dressing and leave for approximately 12 hours. Remove the dressing clean the ulcer with saline or water to remove residual gel and cover again with a moist primary dressing for the rest of the day.

Regranex should be applied once daily to the ulcer until complete healing. If the ulcer does not decrease in size by 30% after 10 weeks or complete healing has not occurred in 20 weeks, reassess treatment with Regranex.

Remove necrotic tissue and calluses to aid drainage and stimulate healing (debridement). Also, reduce the bacterial burden to restore a stable bacterial balance (infection control), and redistribute plantar pressure, to reduce the incidence of ulceration.

Please read the medication guide provided and always speak with your healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Regranex active ingredients

Regranex contains becaplermin as the active ingredient. The gel works by promoting the chemotactic recruitment and proliferation of cells involved in wound healing and enhancing the formation of granulation tissue.

Regranex side effects

The most common side effects of Regranex in clinical studies include:

  • Erythematous rashes
  • Burning sensation, and erythema at the site of application

In rare instances, Regranex can cause more serious adverse effects. These can include:

  • Malignancies distant from the site of application have been reported in postmarketing use

Your doctor will assess the benefits of using Regranex against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Regranex to the FDA. Visit, or call 1-800-FDA-1088.

Regranex drug interactions

Other drugs may interact with Regranex, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medication including any supplements you are taking.

Regranex contraindications

You should not use Regranex if you:

  • Are allergic to the active ingredient becaplermin
  • Are allergic to any of the other ingredients in Regranex
  • Have known neoplasm(s) at the site(s) of application
  • Are younger than 16 years old

Talk to your doctor before using Regranex if you:

  • Are taking any of the medications that could interact with Regranex
  • Have a known malignancy
  • Have blood circulation problems in your lower legs
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Regranex generic

Regranex is the trademark brand name for becaplermin manufactured by Smith & Nephew, Inc. A generic version of becaplermin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Regranex savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.