Rybrevant Coupon & Prices

Is your Rybrevant medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Rybrevant medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Rybrevant cost savings if eligible

With our assistance, you could access the Rybrevant patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Rybrevant patient assistance?

We review each Rybrevant enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Rybrevant patient assistance program?

Our process makes it as easy as possible to apply for the Rybrevant patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Rybrevant, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Rybrevant coupons provider?

NiceRx is not a Rybrevant coupon, Rybrevant discount card, or Rybrevant copay card provider. We do not offer Rybrevant manufacturer coupons, Rybrevant discounts, rebates, Rybrevant savings cards, trial offers, or free Rybrevant samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Rybrevant
  • Your insurance company will not pay for your Rybrevant prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Rybrevant cost without insurance?

Without insurance, Rybrevant costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Rybrevant intravenous solution (50 mg/mL) will cost around $3,100 for a supply of 7 milliliters.

How much does Rybrevant cost with insurance?

The copay for Rybrevant will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Rybrevant?

Rybrevant is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Janssen Pharmaceutical Companies of Johnson & Johnson. It is a bispecific EGF receptor-directed and MET receptor-directed antibody.

Rybrevant is used for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor, EGFR exon 20 insertion mutations, whose disease has progressed on or after platinum-based chemotherapy.

This indication is approved under accelerated approval based on overall response rate (ORR) and duration of response (DOR). Continued approval for this indication may depend upon verification and description of clinical benefit in the confirmatory trials.

What doses of Rybrevant are available?

Rybrevant is available in injection form, in the following doses: 350 mg/7 mL (50 mg/mL) solution in a single-dose vial.

Premedications should be administered as recommended. Rybrevant should be given until disease progression or unacceptable toxicity. Please read the full prescribing information.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Rybrevant active ingredients

The active ingredient of Rybrevant is amivantamab-vmjw, a bispecific antibody that binds to the extracellular domains of EGFR and MET on the surface of tumor cells, allowing for the targeting of these cells.

Rybrevant side effects

The most common side effects of Rybrevant in clinical trials include:

  • Dry skin
  • Paronychia
  • Musculoskeletal pain
  • Dyspnea, stomatitis, cough
  • Nausea, vomiting
  • Fatigue, shortness of breath
  • Edema
  • Dry eye
  • Constipation
  • Blood tests show decreased lymphocytes, albumin, phosphate, potassium, and sodium, increased alkaline phosphatase, glucose, gamma-glutamyl transferase

In rare instances, Rybrevant can cause more serious adverse reactions. These can include:

  • Infusion-Related Reactions (IRR)
  • Interstitial Lung Disease (ILD)/Pneumonitis
  • Dermatologic Adverse Reactions
  • Ocular Toxicity

Your doctor will assess the benefits of using Rybrevant against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Rybrevant to Janssen Biotech, Inc. at 1-800-JANSSEN (1-800-526-7736) or the FDA. Visit, or call 1-800-FDA-1088.

Rybrevant drug interactions

No data is currently available for interactions of Rybrevant with other medicines. Tell your doctor about all the medicines you take, including prescription drugs and over‑the‑counter medicines, vitamins, and herbal supplements.

Rybrevant contraindications

You should not use Rybrevant if you:

  • Are allergic to the active ingredient amivantamab-vmjw
  • Are allergic to any of the other ingredients in Rybrevant
  • Are pregnant or are planning to become pregnant – can cause embryo-fetal toxicity in pregnant women. Females of reproductive potential are advised to use effective contraception
  • Are breastfeeding or are planning to breastfeed
  • Have a history of lung or breathing problems

Rybrevant generic

Rybrevant is the trademark brand name for amivantamab-vmjw manufactured by Janssen Pharmaceutical Companies of Johnson & Johnson. A generic version of amivantamab-vmjw is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Rybrevant savings through NiceRx.

Related conditions

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.