Sarclisa Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Sarclisa cost savings if eligible

If you are eligible to receive your Sarclisa prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Sarclisa patient assistance?

To be eligible for the Sarclisa patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Sarclisa enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Sarclisa patient assistance program?

Applying for the Sarclisa patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Sarclisa, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Sarclisa assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Sarclisa patient assistance program, we will also request your Sarclisa medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Sarclisa coupons provider?

NiceRx does not provide Sarclisa coupons, discount cards, or copay cards. We do not offer printable Sarclisa manufacturer coupons, Sarclisa discounts, rebates, Sarclisa savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Sarclisa medication with NiceRx.

Can NiceRx help me get Sarclisa if I have insurance?

NiceRx may be able to help you access Sarclisa patient assistance if:

  • You have a high copay or coinsurance responsibility for Sarclisa
  • Your insurance company will not pay for your Sarclisa prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Sarclisa cost without insurance?

Sarclisa prices without insurance will vary by retailer. As a guide, Sarclisa intravenous solution (irfc 20 mg/mL) will typically cost around $722 for a supply of 5 milliliters.

How much does Sarclisa cost with insurance?

Your individual healthcare plan will determine the copay of Sarclisa with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Sarclisa?

Sarclisa is a CD38-directed cytolytic antibody manufactured by Sanofi-Aventis. It has FDA approval to be used as a treatment option in combination therapy with pomalidomide and dexamethasone, (Isa-PD) to treat adult patients with relapsed refractory multiple myeloma (cancer of the bone marrow), who have received at least two therapies including lenalidomide and a proteasome inhibitor already.

What doses of Sarclisa are available?

Sarclisa is available in injection form, in the following doses: 100 mg/5 mL (20 mg/mL) solution in single-dose vial, 500 mg/25 mL (20 mg/mL) solution in single-dose vial.

Sarclisa will be given to you by your healthcare provider by intravenous (IV) infusion directly into your vein. It is given in 28-day treatment cycles with the medicines pomalidomide and dexamethasone, or carfilzomib and dexamethasone.

The combination of drugs is used until disease progression or the patient experiences unacceptable toxicity. Please see full the prescribing information, including patient information, and always speak with your healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Sarclisa active ingredients

mechanism of action

Isatuximab-irfc is an IgG1-derived anti-CD38 monoclonal antibody that binds to CD38 released on the surface of hematopoietic and tumor cells, including multiple myeloma cells.

Isatuximab-irfc causes the death of tumor cells and activation of immune effector mechanisms.

Sarclisa side effects

The most common side effects of Sarclisa in clinical trials include:

  • Pneumonia, upper respiratory tract infection, bronchitis, dyspnea
  • Diarrhea
  • Lymphopenia
  • Decreased red blood cells (anemia)
  • Decreased platelet counts (thrombocytopenia)
  • Tiredness and weakness
  • High blood pressure (hypertension)
  • Difficulty sleeping
  • Back pain

In rare instances, Sarclisa can cause more serious adverse effects. These can include:

  • Infusion-related reactions – premedicated patients prior to treatment with acetaminophen, H2 antagonists, diphenhydramine, or equivalent, and dexamethasone
  • Febrile Neutropenia – decreased neutrophil count
  • Second primary malignancies (SPM)
  • Laboratory Test Interference
  • Decreased white blood cell counts – you may have an increased risk of getting certain infections, such as upper and lower respiratory tract infections and urinary tract infections

Your doctor will assess the benefits of using Sarclisa against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Sarclisa to the FDA. Visit, or call 1-800-FDA-1088.

Sarclisa drug interactions

Sarclisa can interact with other medications. These include:

  • Hematology laboratory abnormalities – Sarclisa may interfere with the assays used to monitor M-protein, which may affect a complete response

This list is not exhaustive and other prescription drugs may interact with Sarclisa. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Sarclisa contraindications

You should not use Sarclisa if you:

  • Are allergic to the active ingredient isatuximab-irfc
  • Are allergic or have hypersensitivity to any of the other ingredients in Sarclisa
  • Are pregnant or are planning to become pregnant

Before receiving Sarclisa, tell your healthcare provider about all of your medical conditions, including if you:

  • Are taking any of the medications that could interact with Sarclisa
  • Are breastfeeding or are planning to breastfeed

Sarclisa generic

Sarclisa is the trademark brand name for isatuximab-irfc manufactured by Sanofi-Aventis. A generic version of isatuximab-irfc is OR is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Sarclisa savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.