Segluromet Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Segluromet coupon provider?

NiceRx does not provide Segluromet coupons, discount cards, or copay cards. We do not offer printable Segluromet manufacturer coupons, Segluromet discounts, rebates, Segluromet savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs.

Segluromet patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

How much does Segluromet cost without insurance?

Segluromet prices without insurance will vary by retailer. As a guide, Segluromet oral tablets (2.5 mg-500 mg) will typically cost around $350 for 60 tablets.

How much does Segluromet cost with insurance?

Your individual healthcare plan will determine the copay of Segluromet with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Segluromet?

Segluromet is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Merck. It is a combination of ertugliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, and metformin, a biguanide, used in combination with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Segluromet is not for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

What doses of Segluromet are available?

Segluromet is available in tablet form, in the following doses: Ertugliflozin 2.5 mg and metformin hydrochloride 500 mg, ertugliflozin 2.5 mg and metformin hydrochloride 1,000 mg, ertugliflozin 7.5 mg and metformin hydrochloride 500 mg, ertugliflozin 7.5 mg and metformin hydrochloride 1,000 mg.

Take Segluromet twice daily with meals, with a gradual dose increase. Regular medical checks such as kidney function, liver function, blood sugar, hemoglobin A1c, ketones, complete blood counts, cholesterol, and vitamin B12 should be done before you start taking this medication and during treatment.

Please read the medication guide and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Segluromet active ingredients

Segluromet contains ertugliflozin and metformin as the active ingredients.

Segluromet side effects

The most common side effects of Segluromet in clinical trials include:

  • Genital mycotic infections
  • Diarrhea, flatulence
  • Nausea, vomiting
  • Abdominal discomfort, indigestion
  • Asthenia, headache

In rare instances, Segluromet can cause more serious side effects. These can include:

  • Lactic Acidosis – unusual tiredness, dizziness, severe drowsiness, muscle pain, difficult breathing, irregular heartbeat, or stomach pain with nausea, vomiting, and diarrhea
  • Hypotension (low blood pressure), especially in patients with renal impairment, elderly, or patients taking diuretics
  • Ketoacidosis
  • Acute kidney injury and impairment in renal function
  • Urosepsis and pyelonephritis – monitor for signs of urinary tract infections
  • Lower limb amputation
  • Hypoglycemia (low blood sugar)
  • Vitamin B12 deficiency
  • Increased LDL-C
  • Fournier’s gangrene – a rare but serious bacterial infection in the genital/anal area

Your doctor will assess the benefits of using Segluromet against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Segluromet to the FDA. Visit, or call 1-800-FDA-1088.

Segluromet drug interactions

Segluromet can interact with other medications. These include:

  • Carbonic anhydrase inhibitors may increase the risk of lactic acidosis
  • Drugs that reduce metformin clearance – ranolazine, vandetanib, dolutegravir, and cimetidine
  • Alcohol

This list is not exhaustive and other prescription drugs may interact with Segluromet. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements

Segluromet contraindications

You should not use Segluromet if you:

  • Are allergic to the active ingredients ertugliflozin or metformin
  • Have had an allergic reaction to any of the other ingredients in Segluromet
  • Have severe renal impairment, end-stage kidney disease, or are receiving dialysis
  • Have metabolic acidosis, including diabetic ketoacidosis
  • Are pregnant or are planning to become pregnant

Talk to your doctor about your medical condition before using Segluromet if you:

  • Are taking any of the medications that could interact with Segluromet
  • Have blood problems such as anemia, or vitamin B12 deficiency
  • Have trouble breathing
  • Have heart diseases such as heart failure, or a recent heart attack
  • Have liver problems
  • Have low blood pressure
  • Have yeast infections in the vagina or penis
  • Have blocked or narrowed blood vessels
  • Have diabetic foot ulcers or have had an amputation
  • Are breastfeeding or are planning to breastfeed – metformin passes into breast milk in small amounts

Segluromet generic

Segluromet is the trademark brand name for ertugliflozin and metformin manufactured by Merck. A generic version of ertugliflozin and metformin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Segluromet savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.