Silenor Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Silenor cost savings if eligible

If you are eligible to receive your Silenor prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Silenor patient assistance?

To be eligible for the Silenor patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Silenor enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Silenor patient assistance program?

Applying for the Silenor patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Silenor, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Silenor assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Silenor patient assistance program, we will also request your Silenor medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Silenor coupons provider?

NiceRx does not provide Silenor coupons, discount cards or copay cards. We do not offer printable Silenor manufacturer coupons, Silenor discounts, rebates, Silenor savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Silenor medication with NiceRx.

Can NiceRx help me get Silenor if I have insurance?

NiceRx may be able to help you access Silenor patient assistance if:

  • You have a high copay or coinsurance responsibility for Silenor
  • Your insurance company will not pay for your Silenor prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Silenor cost without insurance?

Silenor prices without insurance will vary by retailer. As a guide, Silenor oral tablets 3 mg will typically cost around $570 for 30 tablets.

How much does Silenor cost with insurance?

Your individual healthcare plan will determine the copay of Silenor with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Silenor?

Silenor is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Somaxon Pharmaceuticals, Inc. Silenor is classed as a miscellaneous anxiolytic, sedative, and hypnotic, tricyclic antidepressant, indicated for the treatment of insomnia characterized by difficulties with sleep maintenance. It is not known how this medication improves sleep but may be due to blocking histamine receptors.

What doses of Silenor are available?

Silenor is available in tablet form, in the following doses: 3 mg and 6 mg tablets.

Take 6 mg as the initial dose, once daily for adults, and 3 mg once daily for the elderly. Take within 30 minutes of bedtime. The total daily dose should not exceed 6 mg. Silenor should not be taken within 3 hours of a meal as it may make you sleepy the next day if taken with or right after a meal.

Please read the full prescribing information and medication guide and always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Silenor active ingredients

Silenor contains doxepin as the active ingredient.

Silenor side effects

The most common side effects of Silenor in clinical trials compared to placebo include:

  • Drowsiness or tiredness
  • Somnolence
  • Sedation
  • Nausea
  • Upper respiratory tract infection

In rare instances, Silenor can cause more serious adverse effects. These can include:

  • Abnormal thinking, behavioral changes, complex behaviors, which may include “sleep-driving” and hallucinations
  • Depression – worsening of depression or suicidal thoughts
  • CNS-depressant effects – can impair alertness and motor coordination

Your doctor will assess the benefits of using Silenor against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Silenor to the FDA. Visit, or call 1-800-FDA-1088.

Silenor drug interactions

Silenor can interact with other medications. These include:

  • Monoamine oxidase inhibitors (MAO inhibitors) – Silenor should not be given to patients on MAOIs within the past two weeks
  • Cimetidine
  • Alcohol – increased sedative effects
  • CNS depressants (central nervous system) and sedating antihistamines
  • Tolazamide – a case of severe hypoglycemia has been reported

This list is not exhaustive and other prescription drugs may interact with Silenor. Tell your healthcare provider about all of the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Silenor contraindications

You should not use Silenor if you:

  • Are allergic to the active ingredient doxepin
  • Have had an allergic reaction to any of the other ingredients in Silenor
  • Have untreated narrow-angle glaucoma
  • Have severe urinary retention

Talk to your doctor about all of your medical conditions, or before using Silenor if you:

  • Are taking any of the medications that could interact with Silenor
  • Have severe sleep apnea
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are geriatric – the recommended starting dose is 3 mg
  • Have hepatic impairment or a tendency to urinary retention

Silenor generic

Silenor is the trademark brand name for doxepin manufactured by Somaxon Pharmaceuticals, Inc. A generic version of doxepin is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Silenor savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.