Sirturo Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Sirturo cost savings if eligible

If you are eligible for the Sirturo patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Sirturo through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Sirturo patient assistance program?

You could receive your Sirturo without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Sirturo patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Sirturo.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Sirturo patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Sirturo medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Sirturo coupon provider?

At NiceRx, we help eligible individuals access the Sirturo patient assistance program. This means that we are not a Sirturo coupon, a Sirturo discount card, or a Sirturo copay card provider. We do not offer any medication trial offers, or free Sirturo samples.

Can NiceRx help me get Sirturo cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Sirturo medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Sirturo cost without insurance?

Sirturo costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Sirturo oral tablets 20 mg will typically cost around $2,000 for 60 tablets. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Sirturo cost with insurance?

The copay of Sirturo will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Sirturo?

Sirturo is an FDA (U.S. Food and Drug Administration) approved medication manufactured for Janssen Therapeutics. It is a diarylquinoline antimycobacterial drug indicated as part of combination therapy in adults with pulmonary multi-drug resistant tuberculosis (MDR-TB). Sirturo is used when an effective treatment regimen cannot otherwise be provided.

Sirturo has certain limitations of use. It is not indicated for the treatment of latent, extra-pulmonary or drug-sensitive tuberculosis, or for pediatric patients less than 5 years of age and/or weighing less than 15 kg.

What doses of Sirturo are available?

Sirturo is available in tablet form, in the following doses: 100 mg.

The recommended dose is 400 mg once daily for 2 weeks followed by 200 mg 3 times per week for 22 weeks. Take Sirturo with food, and swallow the tablets whole with water.

Sirturo should be initiated and monitored by a physician experienced in the management of multi-drug resistant Mycobacterium tuberculosis.

Please see the full prescribing information for the complete boxed warning and the medication guide, and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Sirturo active ingredients

The active ingredient in Sirturo, bedaquiline fumarate, blocks an enzyme inside the M. tuberculosis bacteria called ATP synthase, which the bacteria need to generate energy. Without the ability to generate energy, the bacteria die.

Sirturo side effects

The most common side effects of Sirturo in clinical trials compared to placebo include:

  • Nausea
  • Abdominal pain
  • Arthralgia (joint pain)
  • Headache
  • Hemoptysis
  • Chest pain

In rare instances, Sirturo can cause more serious side effects. These can include:

  • QT prolongation – monitor ECGs frequently, discontinue if significant ventricular arrhythmia or a QTcF interval > 500 ms develops
  • Hepatotoxicity – elevated liver enzymes

Your doctor will assess the benefits of using Sirturo against your risk of adverse effects. Patients are encouraged to report negative side effects or adverse reactions of Sirturo to the FDA. Visit, or call 1-800-FDA-1088.

Sirturo drug interactions

Sirturo can interact with other medications. These include:

  • Drugs that prolong the QT interval may cause additive QT prolongation – fluoroquinolones and macrolide antibacterial drugs and the antimycobacterial drug, clofazimine
  • Systemic potent CYP3A4 inducers – avoid co-administration of rifampin, rifapentine, and rifabutin
  • Moderate CYP3A4 inducers such as efavirenz
  • Systemic strong CYP3A4 inhibitors such as ketoconazole or itraconazole

This list is not exhaustive and other prescription drugs may interact with Sirturo.

Sirturo contraindications

You should not use Sirturo if you:

  • Are allergic to the active ingredient bedaquiline
  • Are allergic to any of the other ingredients in Sirturo

Talk to your doctor before using Sirturo if you:

  • Are taking any of the medications that could interact with Sirturo
  • Have severe renal impairment
  • Have severe hepatic impairment
  • Have a history of Torsade de Pointes
  • Have congenital long QT syndrome
  • Have hypothyroidism
  • Suffer from bradyarrhythmias
  • Have uncompensated heart failure
  • Have serum calcium, magnesium, or potassium levels below the lower limits of normal
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

 Sirturo generic

Sirturo is the trademark brand name for bedaquiline manufactured for Janssen Therapeutics. A generic version of bedaquiline is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Sirturo savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.