Skytrofa Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Skytrofa cost savings if eligible

If you are eligible for the Skytrofa patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Skytrofa prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Skytrofa patient assistance program?

We will review your application to determine whether you are eligible for the Skytrofa patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Skytrofa patient assistance program?

We make it as easy as possible to apply for the Skytrofa patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Skytrofa. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Skytrofa assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Skytrofa patient assistance program, and we will automatically request your Skytrofa medication refills for up to 1 year.

Is NiceRx a Skytrofa coupon provider?

We are a service provider that helps eligible individuals access the Skytrofa patient assistance program. That means that we do not offer printable Skytrofa manufacturer coupons, Skytrofa discounts, or free Skytrofa samples. We are not a Skytrofa coupon provider or Skytrofa discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Skytrofa cheaper if I have insurance?

We may be able to help you to access Skytrofa patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Skytrofa medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Skytrofa cost without insurance?

Skytrofa cost without insurance will vary depending on where you buy it. As a guide, Skytrofa subcutaneous injection tcgd 3 mg usually costs $2,800 for 4 injections. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Skytrofa cost with insurance?

The copay for Skytrofa with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Skytrofa?

Skytrofa is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Ascendis Pharma, Inc. Skytrofa is a human growth hormone (HGH) indicated for the once-weekly treatment of pediatric patients 1 year and older who weigh at least 11.5 kg for growth hormone deficiency (GHD) and who have growth failure due to inadequate secretion of endogenous growth hormone.

What doses of Skytrofa are available?

Skytrofa is available as a lyophilized powder for injection, in the following doses: 3 mg, 3.6 mg, 4.3 mg, 5.2 mg, 6.3 mg, 7.6 mg, 9.1 mg, 11 mg, and 13.3 mg.

Skytrofa should be administered subcutaneously into the abdomen, buttock, or thigh with a regular rotation of the injection sites. The recommended dose for treatment-naive patients and patients switching from daily somatropin therapy is 0.24 mg/kg body weight, given once weekly. Wait at least 8 hours between the final dose of daily somatropin and the first dose of once-weekly Skytrofa when switching from daily somatropin therapy to once-weekly.

Please read the full prescribing information for instructions on the preparation and administration of Skytrofa and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Skytrofa active ingredients

Skytrofa is a long-acting prodrug of the human growth hormone, somatropin. FDA approval was based on data from the multicenter, randomized, open-label, parallel-group phase 3 heiGHt trial which compared the use of once-weekly lonapegsomatropin-tcgd to daily somatropin in treatment-naïve, prepubertal patients with growth hormone deficiency. Results showed that lonapegsomatropin-tcgd met the noninferiority criteria for the primary endpoint showing a greater annualized height velocity compared with somatropin.

Skytrofa side effects

The most common side effects of Skytrofa in clinical trials include:

  • Viral infection
  • Pyrexia
  • Cough
  • Nausea and vomiting
  • Hemorrhage, diarrhea, abdominal pain
  • Arthralgia and arthritis

In rare instances, Skytrofa can cause more serious side effects. These can include:

  • Increases in the growth rate and progression of existing scoliosis – monitor patients with a history of scoliosis for disease progression
  • Severe Hypersensitivity
  • Increased risk of neoplasms
  • Glucose intolerance and diabetes mellitus may be unmasked
  • Intracranial hypertension
  • Fluid Retention
  • Hypoadrenalism
  • Hypothyroidism
  • Slipped capital femoral epiphysis – evaluate children with the onset of a limp or persistent hip/knee pain
  • Pancreatitis

Your caregiver will assess the benefits of using Skytrofa against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Skytrofa to the FDA. Visit, or call 1-800-FDA-1088.

Skytrofa drug interactions

Skytrofa can interact with other medications. These include:

  • Replacement glucocorticoid treatment
  • Pharmacologic glucocorticoid therapy and supraphysiologic glucocorticoid treatment
  • Cytochrome P450-metabolized drugs
  • Oral estrogen
  • Insulin and/or other antihyperglycemic agents

This list is not exhaustive and other prescription drugs may interact with Skytrofa.

Skytrofa contraindications

You should not use Skytrofa if you:

  • Are allergic to the active ingredient lonapegsomatropin-tcgd
  • Are allergic to any of the other ingredients in Skytrofa
  • Have an acute critical illness
  • Are a child with closed epiphysis
  • Have active malignancy
  • Have active proliferative or severe non-proliferative diabetic retinopathy
  • Are a child with Prader-Willi syndrome who is severely obese or has severe respiratory impairment due to the risk of sudden death

Talk to your doctor before using Skytrofa if you:

  • Are taking any of the medications that could interact with Skytrofa
  • Have diabetes
  • Have a head injury or brain tumor
  • Have a pituitary gland disorder
  • Have an underactive thyroid
  • Have abnormal curvature of the spine (scoliosis)
  • Have breathing problems, such as sleep apnea (breathing stops during sleep)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Skytrofa generic

Skytrofa is the trademark brand name for lonapegsomatropin-tcgd manufactured by Ascendis Pharma, Inc. A generic version of lonapegsomatropin-tcgd is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Skytrofa savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.