Symlinpen Coupon & Prices

Is your Symlinpen medication too expensive?

Get notified when Symlinpen medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Your monthly Symlinpen cost savings if eligible

If you are eligible for the Symlinpen patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Symlinpen through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Symlinpen patient assistance program?

You could receive your Symlinpen without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Symlinpen patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Symlinpen.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Symlinpen patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Symlinpen medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Symlinpen coupon provider?

At NiceRx, we help eligible individuals access the Symlinpen patient assistance program. This means that we are not a Symlinpen coupon, a Symlinpen discount card, or a Symlinpen copay card provider. We do not offer any medication trial offers, or free Symlinpen samples.

Can NiceRx help me get Symlinpen if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Symlinpen medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Symlinpen cost without insurance?

Symlinpen costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Symlinpen 120 subcutaneous solution (1000 mcg/mL) will typically cost around $1,200 for 5.4 milliliters. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Symlinpen cost with insurance?

The copay of Symlinpen will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Symlinpen?

Symlinpen is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Amylin Pharmaceuticals. Symlin is an amylin analog indicated for patients with type 1 or type 2 diabetes who use mealtime insulin and have failed to achieve desired glycemic control despite optimal insulin therapy.

Symlin use with insulin causes an increased risk of severe hypoglycemia (low blood sugar). Symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

What doses of Symlinpen are available?

Symlinpen is available in injection form, in the following doses:

  • 1.5 mL SymlinPen 60 disposable multidose pen-injector, (1000 mcg/mL) for 15, 30, 45, and 60 mcg doses
  • 2.7 mL SymlinPen 120 disposable multidose pen-injector, (1000 mcg/mL) for 60 and 120 mcg doses

Reduce mealtime insulin dose by 50% when initiating Symlin. Monitor glucoses regularly and individualize subsequent insulin dose adjustments. For type 1 diabetes start at 15 mcg subcutaneously before major meals. Increase in 15 mcg increments to a maximum premeal dose of 30 or 60 mcg. If not tolerated, reduce to 30 mcg. For type 2 diabetes start at 60 mcg subcutaneously before major meals, increasing to 120 mcg before meals, as tolerated.

If you are storing this drug in the refrigerator, remove it and allow it to come to room temperature before injecting. Please read the medication guide, and always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Symlinpen active ingredients

Symlinpen contains pramlintide acetate as the active ingredient.

Symlinpen side effects

The most common side effects of Symlinpen in clinical trials include:

  • Redness, swelling and itching at the injection site
  • Nausea, vomiting, headache
  • Loss of appetite, stomach pain, anorexia

In rare instances, Symlinpen can cause more serious side effects. These can include:

  • Severe hypoglycemia – increased risk particularly for type 1 diabetes

Your doctor will assess the benefits of using Symlinpen against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Symlinpen to the FDA. Visit, or call 1-800-FDA-1088.

Symlinpen drug interactions

Symlinpen can interact with other medications. These include:

  • Insulin – mixing can alter the pharmacokinetics of both products. Administer as separate injections
  • Diabetes drugs, including alpha glucosidase inhibitors such as acarbose and miglitol
  • Drugs for high blood pressure that may make it harder to notice symptoms of low blood sugar, such as clonidine and guanethidine
  • Drugs that slow down or speed up the movement of food through your stomach such as atropine, exenatide, and metoclopramide
  • Antibiotics
  • Birth control pills
  • Pain relievers such as acetaminophen
  • Beta blockers such as metoprolol, or propranolol

This list is not exhaustive and other prescription drugs may interact with Symlinpen. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Symlinpen contraindications

You should not use Symlinpen if you:

  • Are allergic to the active ingredient pramlintide
  • Have had an allergic reaction to any of the other ingredients in Symlinpen
  • Have confirmed gastroparesis

Talk to your doctor before using Symlinpen if you:

  • Are taking any of the medications that could interact with Symlinpen
  • Have a history of delayed gastric emptying
  • Have problems with your vision
  • Are unable to check your blood sugars regularly
  • Have had severe hypoglycemia more than once in the past 6 months
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Symlinpen generic

Symlinpen is the trademark brand name for pramlintide manufactured by Amylin Pharmaceuticals. A generic version of pramlintide is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Symlinpen savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.