Synthroid Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Synthroid cost savings if eligible

If you are eligible for the Synthroid patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Synthroid prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Synthroid patient assistance program?

We will review your application to determine whether you are eligible for the Synthroid patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Synthroid patient assistance program?

We make it as easy as possible to apply for the Synthroid patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Synthroid. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Synthroid assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Synthroid patient assistance program, and we will automatically request your Synthroid medication refills for up to 1 year.

Is NiceRx a Synthroid coupon provider?

We are a service provider that helps eligible individuals access the Synthroid patient assistance program. That means that we do not offer printable Synthroid manufacturer coupons, Synthroid discounts, or free Synthroid samples. We are not a Synthroid coupon provider or Synthroid discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Synthroid cheaper if I have insurance?

We may be able to help you to access Synthroid patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Synthroid medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Synthroid cost without insurance?

Synthroid cost without insurance will vary depending on where you buy it. As a guide, Synthroid oral tablet 50 mcg usually costs $145 for 90 tablets. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Synthroid cost with insurance?

The copay for Synthroid with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Synthroid?

Synthroid is an FDA (U.S. Food and Drug Administration) approved medication manufactured by AbbVie, Inc. It is a thyroid medicine that replaces the hormone that would normally be produced by your thyroid gland. Symptoms of low thyroid hormone levels include tiredness, muscle aches, constipation, dry skin, weight gain, slow heartbeat, or sensitivity to cold. Synthroid (levothyroxine sodium) is used:

  • As replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism
  • Alongside surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer

Synthroid is not recommended for the suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients, or for treatment of hypothyroidism during the recovery phase of subacute thyroiditis. Synthroid is not for the treatment of obesity or for weight loss. Doses above those required for daily hormonal requirements may produce serious or even life-threatening toxicity.

What doses of Synthroid are available?

Synthroid is available in tablet form, in the following doses: 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, and 300 mcg.

Take Synthroid once daily, on an empty stomach, half to one hour before breakfast. Take Synthroid at least 4 hours before or after drugs that are known to affect absorption. The starting dose will depend on a number of factors, including age, body weight, cardiovascular status, and other medications being taken. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and take your next dose at the normal time.

Always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Synthroid active ingredients

Synthroid contains levothyroxine as the active ingredient.

Synthroid side effects

The most common side effects of Synthroid in clinical trials include:

  • Irregular heartbeats, myocardial infarction
  • Dyspnea
  • Muscle spasm, muscle weakness
  • Headache
  • Anxiety, irritability
  • Trouble sleeping, tiredness
  • Increased appetite, weight loss
  • Diarrhea
  • Intolerance to heat
  • Menstrual changes
  • Skin rash
  • Chest pain, shortness of breath
  • Weight loss
  • Partial hair loss

Synthroid can cause more serious side effects. These can include:

  • Cardiac adverse reactions in the elderly and in patients with underlying cardiovascular disease
  • Acute adrenal crisis in patients with concomitant adrenal insufficiency
  • Hyperthyroidism or incomplete treatment of hypothyroidism
  • Worsening of diabetic control
  • Decreased bone mineral density

Your doctor will assess the benefits of using Synthroid against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Synthroid to the FDA. Visit, or call 1-800-FDA-1088.

Synthroid drug interactions

Synthroid can interact with other medications. These include:

  • Cholestyramine, colestipol, colesevelam
  • Antacids
  • Sucralfate
  • Simethicone, iron, sodium polystyrene sulfonate
  • Calcium supplements
  • Orlistat, lanthanum, sevelamer

This list is not exhaustive and other prescription drugs may interact with Synthroid. Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.

Synthroid contraindications

You should not use Synthroid if you:

  • Are allergic to the active ingredient levothyroxine
  • Have had an allergic reaction to any of the other ingredients in Synthroid
  • Have uncorrected adrenal insufficiency

Talk to your doctor about your medical condition before using Synthroid if you:

  • Are taking any of the medications that could interact with Synthroid
  • Have a thyroid nodule
  • Have heart disease, a blood clot, or a blood-clotting disorder
  • Have diabetes
  • Have kidney disease
  • Have anemia
  • Have osteoporosis
  • Have problems with your pituitary gland
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Synthroid generic

Synthroid is the trademark brand name for levothyroxine manufactured by AbbVie, Inc. A generic version of levothyroxine is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Synthroid savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.