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Takhzyro Patient assistance program

Is your Takhzyro medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Takhzyro medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

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  • An introduction to NiceRx
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  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Takhzyro cost savings if eligible

If you are eligible for the Takhzyro patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Takhzyro prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Takhzyro patient assistance program?

We will review your application to determine whether you are eligible for the Takhzyro patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Takhzyro patient assistance program?

We make it as easy as possible to apply for the Takhzyro patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Takhzyro. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Takhzyro assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Takhzyro patient assistance program, and we will automatically request your Takhzyro medication refills for up to 1 year.

Is NiceRx a Takhzyro coupons provider?

We are a service provider that helps eligible individuals access the Takhzyro patient assistance program. That means that we do not offer printable Takhzyro manufacturer coupons, Takhzyro discounts, or free Takhzyro samples. We are not a Takhzyro coupon provider or Takhzyro discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Takhzyro if I have insurance?

We may be able to help you to access Takhzyro patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Takhzyro medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Takhzyro cost without insurance?

Takhzyro cost without insurance will vary depending on where you buy it. As a guide, Takhzyro subcutaneous solution (300 mg/2 mL) usually costs $24,500 for a supply of 2 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Takhzyro cost with insurance?

The copay for Takhzyro with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Takhzyro?

Takhzyro is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire Pharmaceuticals Ireland Limited.

Takhzyro is a plasma kallikrein inhibitor (monoclonal antibody) used for prophylaxis to prevent attacks of hereditary angioedema (HAE) in patients 12 years of age. HAE is a rare genetic disorder estimated to affect about 1 in 50,000 people worldwide.

What doses of Takhzyro are available?

Takhzyro is available as an injection, in the following doses: 300 mg/2 mL (150 mg/mL) solution in a single-dose vial.

Takhzyro is for subcutaneous injection use only, given in the abdomen, thigh, or upper arm. The recommended starting dose is Takhzyro 300 mg every 2 weeks. A 4-week dosing interval may be considered if the patient is attack-free for more than 6 months. A healthcare professional may teach you how to use the medication yourself.

Prepare your injection only when you are ready to use it within the next 2 hours. Store in the refrigerator. Take the medicine out of the refrigerator and allow it to reach room temperature for 15 minutes before injecting your dose.

Use Takhzyro treatment exactly as it was prescribed for you. Read and carefully follow any prescribing information and instructions for use provided with your medicine. Do not use Takhzyro if you do not understand all the instructions for proper use. Always speak with your caregiver about any changes to your dose so they can monitor and evaluate your condition.

Takhzyro active ingredients

Takhzyro contains the active ingredient lanadelumab-flyo, a fully human monoclonal antibody (IgG1/κ-light chain) that binds plasma kallikrein and inhibits its proteolytic activity.

Plasma kallikrein is a protease that cuts high-molecular-weight-kininogen to form cleaved HMWK and bradykinin, a potent vasodilator that increases vascular permeability resulting in swelling and pain associated with HAE attacks. In patients with HAE due to a lack of C1-inhibitor or dysfunction, normal control of plasma kallikrein activity is not present. This leads to uncontrolled increases in plasma kallikrein activity and causes angioedema attacks. Lanadelumab-flyo decreases plasma kallikrein activity to control excess bradykinin production and reduce the number of HAE attacks.

Takhzyro side effects

The most common side effects of Takhzyro in clinical trials include:

  • Injection site reactions
  • Upper respiratory infections
  • Headache, myalgia, dizziness
  • Diarrhea
  • Rash

In rare instances, Takhzyro can cause more serious side effects. These can include:

  • Hypersensitivity reactions – stop treatment

Takhzyro can cause serious allergic reactions – get emergency help if you have symptoms of hives, fast heartbeats, problems breathing, feeling light-headed, swelling of your face, lips, tongue, or throat.

Your doctor will assess the benefits of using Takhzyro against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Takhzyro to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Takhzyro drug interactions

Currently, there is no data regarding drug interactions with Takhzyro however, tell your doctor about all your current medicines including prescription drugs and over-the-counter medicines, vitamins, and herbal products you start or stop using.

Takhzyro contraindications

You should not use Takhzyro if you:

  • Are allergic to the active ingredient lanadelumab-flyo
  • Are allergic to any of the other ingredients in Takhzyro
  • Are younger than 12 years old

Talk to your doctor before using Takhzyro if you:

  • Are taking any of the medications that could interact with Takhzyro
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Takhzyro generic

Takhzyro is the trademark brand name for lanadelumab-flyo manufactured by Shire Pharmaceuticals Ireland Limited. A generic version of lanadelumab-flyo is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Takhzyro savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.