Takhzyro Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Takhzyro cost savings if eligible

If you are eligible for the Takhzyro patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Takhzyro prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Takhzyro patient assistance program?

We will review your application to determine whether you are eligible for the Takhzyro patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Takhzyro patient assistance program?

We make it as easy as possible to apply for the Takhzyro patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Takhzyro. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Takhzyro assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Takhzyro patient assistance program, and we will automatically request your Takhzyro medication refills for up to 1 year.

Is NiceRx a Takhzyro coupons provider?

We are a service provider that helps eligible individuals access the Takhzyro patient assistance program. That means that we do not offer printable Takhzyro manufacturer coupons, Takhzyro discounts, or free Takhzyro samples. We are not a Takhzyro coupon provider or Takhzyro discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Takhzyro if I have insurance?

We may be able to help you to access Takhzyro patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Takhzyro medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Takhzyro cost without insurance?

Takhzyro cost without insurance will vary depending on where you buy it. As a guide, Takhzyro subcutaneous solution (300 mg/2 mL) usually costs $24,500 for a supply of 2 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Takhzyro cost with insurance?

The copay for Takhzyro with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Takhzyro?

Takhzyro is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire Pharmaceuticals Ireland Limited.

Takhzyro is a plasma kallikrein inhibitor (monoclonal antibody) used for prophylaxis to prevent attacks of hereditary angioedema (HAE) in patients 12 years of age. HAE is a rare genetic disorder estimated to affect about 1 in 50,000 people worldwide.

What doses of Takhzyro are available?

Takhzyro is available as an injection, in the following doses: 300 mg/2 mL (150 mg/mL) solution in a single-dose vial.

Takhzyro is for subcutaneous injection use only, given in the abdomen, thigh, or upper arm. The recommended starting dose is Takhzyro 300 mg every 2 weeks. A 4-week dosing interval may be considered if the patient is attack-free for more than 6 months. A healthcare professional may teach you how to use the medication yourself.

Prepare your injection only when you are ready to use it within the next 2 hours. Store in the refrigerator. Take the medicine out of the refrigerator and allow it to reach room temperature for 15 minutes before injecting your dose.

Use Takhzyro treatment exactly as it was prescribed for you. Read and carefully follow any prescribing information and instructions for use provided with your medicine. Do not use Takhzyro if you do not understand all the instructions for proper use. Always speak with your caregiver about any changes to your dose so they can monitor and evaluate your condition.

Takhzyro active ingredients

Takhzyro contains the active ingredient lanadelumab-flyo, a fully human monoclonal antibody (IgG1/κ-light chain) that binds plasma kallikrein and inhibits its proteolytic activity.

Plasma kallikrein is a protease that cuts high-molecular-weight-kininogen to form cleaved HMWK and bradykinin, a potent vasodilator that increases vascular permeability resulting in swelling and pain associated with HAE attacks. In patients with HAE due to a lack of C1-inhibitor or dysfunction, normal control of plasma kallikrein activity is not present. This leads to uncontrolled increases in plasma kallikrein activity and causes angioedema attacks. Lanadelumab-flyo decreases plasma kallikrein activity to control excess bradykinin production and reduce the number of HAE attacks.

Takhzyro side effects

The most common side effects of Takhzyro in clinical trials include:

  • Injection site reactions
  • Upper respiratory infections
  • Headache, myalgia, dizziness
  • Diarrhea
  • Rash

In rare instances, Takhzyro can cause more serious side effects. These can include:

  • Hypersensitivity reactions – stop treatment

Takhzyro can cause serious allergic reactions – get emergency help if you have symptoms of hives, fast heartbeats, problems breathing, feeling light-headed, swelling of your face, lips, tongue, or throat.

Your doctor will assess the benefits of using Takhzyro against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Takhzyro to the FDA. Visit, or call 1-800-FDA-1088.

Takhzyro drug interactions

Currently, there is no data regarding drug interactions with Takhzyro however, tell your doctor about all your current medicines including prescription drugs and over-the-counter medicines, vitamins, and herbal products you start or stop using.

Takhzyro contraindications

You should not use Takhzyro if you:

  • Are allergic to the active ingredient lanadelumab-flyo
  • Are allergic to any of the other ingredients in Takhzyro
  • Are younger than 12 years old

Talk to your doctor before using Takhzyro if you:

  • Are taking any of the medications that could interact with Takhzyro
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Takhzyro generic

Takhzyro is the trademark brand name for lanadelumab-flyo manufactured by Shire Pharmaceuticals Ireland Limited. A generic version of lanadelumab-flyo is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Takhzyro savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.