Tegsedi Coupon & Prices

Is your Tegsedi medication too expensive?

Get notified when Tegsedi medication is added to NiceRx

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Tegsedi coupon provider?

NiceRx does not provide Tegsedi coupons, discount cards, or copay cards. We do not offer printable Tegsedi manufacturer coupons, Tegsedi discounts, rebates, Tegsedi savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Tegsedi medication with NiceRx.

Tegsedi patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Tegsedi cheaper if I have insurance?

How much does Tegsedi cost without insurance?

Tegsedi prices without insurance will vary by retailer.

How much does Tegsedi cost with insurance?

Your individual healthcare plan will determine the copay of Tegsedi with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Tegsedi?

Tegsedi is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Ionis Pharmaceuticals, Inc., and Akcea Therapeutics, Inc. It is a transthyretin (TTR)-directed antisense oligonucleotide used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis (HATTR amyloidosis) in adult patients.

A liver transplant is the standard therapy as TTR is mainly produced in the liver. Tegsedi inhibits the production of TTR. Tegsedi helps to improve the course of neurologic disease and the quality of life in patients. Tegsedi is available only through a restricted program called the TEGS EDI REMS Program.

What doses of Tegsedi are available?

Tegsedi is available in injection form, in the following doses: 284 mg/ 1.5 mL in a single-dose prefilled syringe.

The recommended dose is one injection once weekly, given under the skin in the belly, upper thigh, or upper arm. Laboratory tests must be taken before, during, and after discontinuation of treatment.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Tegsedi active ingredients

Tegsedi contains inotersen as the active ingredient.

Tegsedi side effects

The most common side effects of Tegsedi in clinical trials compared to placebo include:

  • Injection site reactions
  • Nausea, headache
  • Fatigue
  • Thrombocytopenia (low platelet count) – symptoms of thrombocytopenia include unusual or prolonged bleeding which can be life-threatening, neck stiffness, or atypical severe headache. You are recommended to receive glucocorticoids to reverse platelet decline and fever

In rare instances, Tegsedi can cause more serious adverse effects. These can include:

  • Stroke and cervicocephalic arterial dissection
  • Inflammatory and immune effects
  • Liver effects – monitor alanine aminotransferase, aspartate aminotransferase, and total bilirubinHypersensitivity reactions
  • Uninterpretable platelet counts – reaction between antiplatelet, antibodies, and ethylenediaminetetra-acetic acid
  • Reduced serum Vitamin A levels – symptoms include reduced night vision or night blindness, persistent dry eyes, eye inflammation, corneal inflammation or ulceration, and corneal thickening. Vitamin A supplementation is advised
  • Renal toxicity – glomerulonephritis may require immunosuppressive treatment and may result in dialysis-dependent renal failure

Your caregiver will assess the benefits of using Tegsedi against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Tegsedi to the FDA. Visit, or call 1-800-FDA-1088.

Tegsedi drug interactions

Tegsedi can interact with other medications. These include:

  • Antiplatelet drugs
  • Non-steroidal anti-inflammatory drugs
  • Anticoagulants

This list is not exhaustive and other prescription drugs may interact with Tegsedi.

Tegsedi contraindications

You should not use Tegsedi if you:

  • Are allergic to the active ingredient inotersen
  • Have had an allergic reaction to any of the other ingredients in Tegsedi
  • Have a history of acute glomerulonephritis caused by Tegsedi
  • Have low levels of platelets in your blood
  • Have kidney problems caused by using Tegsedi in the past

Talk to your doctor before using Tegsedi if you:

  • Are taking any of the medications that could interact with Tegsedi
  • Have had a liver transplant
  • Have a bleeding or blood clotting disorder
  • Have renal impairment (reduced renal function)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Tegsedi generic

Tegsedi is the trademark brand name for inotersen manufactured by Ionis Pharmaceuticals, Inc., and Akcea Therapeutics, Inc. A generic version of inotersen is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Tegsedi savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.