Tepezza Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Tepezza cost savings if eligible

The Tepezza patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Tepezza, regardless of the retail price.

Am I eligible for the Tepezza patient assistance program?

To find out if you are eligible for Tepezza assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Tepezza patient assistance program?

Our application process aims to make it as easy as possible to apply for the Tepezza patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Tepezza.

NiceRx will review your application and determine whether you may be eligible for Tepezza assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Tepezza patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Tepezza.

Is NiceRx a Tepezza coupons provider?

NiceRx is a service provider that helps eligible individuals access the Tepezza patient assistance program. We do not offer trial offers or free Tepezza samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Tepezza coupons, discount cards, or Tepezza copay cards.

Can NiceRx help me get Tepezza if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Tepezza medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Tepezza cost without insurance?

Tepezza prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Tepezza intravenous powder for injection 500 mg typically costs $15,500 for 1 powder for injection.

How much does Tepezza cost with insurance?

The copay for Tepezza will vary by the terms of your healthcare plan. To find out what you might need to pay for Tepezza with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Tepezza?

Tepezza is an FDA (Food and Drug Administration) – approved medication manufactured by Horizon Therapeutics. Tepezza is used for the treatment of thyroid eye disease (TED) in adults. TED is typically seen in people with hyperthyroidism (an overactive thyroid gland) that are caused by Graves’ disease. TED is also sometimes called Graves’ eye disease, Graves’ ophthalmopathy, or Graves’ orbitopathy.

Tepezza helps to reduce proptosis (eye-bulging) and (diplopia) double vision. It also improves the signs and symptoms of Thyroid eye disease (TED), which includes eye pain, redness, and swelling.

What doses of Tepezza are available?

Tepezza is available as a lyophilized powder in a single-dose vial for reconstitution in the following doses: 500 mg.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Tepezza active ingredients

The active drug teprotumumab is a monoclonal antibody. It is classed as an insulin-like growth factor-1 receptor inhibitor. This means it prevents IGF-1R from being activated. With TED, your immune system attacks cells in the back of your eyes. This attack activates IGF-1R, which is thought to have a key part in the inflammation involved. Tepezza works by binding to IGF-1R and stopping it from being activated by your immune system. This may prevent inflammation and the creation of tissue, both of which cause symptoms of TED.

Tepezza side effects

The most common side effects observed in clinical trials by Tepezza include:

  • Diarrhea
  • Stomach cramps
  • Sudden bowel movements
  • A feeling of not completely emptying your bowels
  • Rectal bleeding
  • High blood sugar – increased thirst, increased urination, dry mouth, fruity breath odor

In rare instances, Tepezza can cause more serious side effects. These can include:

  • Muscle spasms
  • Nausea, diarrhea
  • Headache, feeling tired
  • High blood sugar
  • Hair loss
  • Problems with hearing
  • Dry skin
  • Altered sense of taste
  • Infusion reactions may occur such as a short-term increase in your blood pressure, increased heart rate, difficulty breathing, headache, muscle pain, or feeling hot

Your healthcare professional will assess the benefits of using Tepezza against your risk of side effects.

Patients are encouraged to report negative side effects or adverse reactions of Tepezza to the FDA (The Food and Drug Administration). Visit, or call 1-800-FDA-1088.

Tepezza drug interactions

Tepezza can interact with other medications. These include:

  • Aspirin
  • Atorvastatin
  • Calcium / vitamin D
  • Clopidogrel
  • Famotidine
  • Gabapentin
  • Ibuprofen
  • Levothyroxine
  • Multivitamin
  • Prednisone

This list is not exhaustive and other drugs may interact with Tepezza. Speak to your doctor for further medical advice or about other medicines you take, including prescription and over-the-counter medicines, vitamins, dietary and herbal supplements.

Tepezza contraindications

You should not use Tepezza if you:

  • Are allergic to the active ingredient teprotumumab-trbw
  • Are allergic to any of the other ingredients in Tepezza
  • Are pregnant or are planning to become pregnant – use birth control while you are receiving Tepezza and for at least 6 months after your last dose

Talk to your doctor before using Tepezza if you:

  • Are taking any of the medications that could interact with Tepezza
  • Inflammatory bowel disease (IBD) such as Crohn’s disease
  • Diabetes or hyperglycemia (high blood sugar)
  • Are breastfeeding or are planning to breastfeed

Tepezza generic

Tepezza is the trademark brand name for teprotumumab-trbw manufactured by Horizon Therapeutics. A generic version of teprotumumab-trbw is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Tepezza savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.