TissueBlue Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a TissueBlue coupon provider?

NiceRx does not provide TissueBlue coupons, discount cards, or copay cards. We do not offer printable TissueBlue manufacturer coupons, TissueBlue discounts, rebates, TissueBlue savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your TissueBlue medication with NiceRx.

TissueBlue patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get TissueBlue cheaper if I have insurance?

How much does TissueBlue cost without insurance?

TissueBlue prices without insurance will vary by retailer.

How much does TissueBlue cost with insurance?

Your individual healthcare plan will determine the copay of TissueBlue with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is TissueBlue?

TissueBlue is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Dutch Ophthalmic Research Centre (DORC). TissueBlue (generic name, Brilliant Blue G Ophthalmic Solution) 0.025% is a disclosing agent used to stain the internal limiting membrane (ILM), which forms the inner layer of the retina.

Cellular growth and spread on the ILM can form vision-impairing epiretinal membranes (ERM) and macular holes. Removal of the ILM can relieve symptoms of macular distortion. TissueBlue is injected onto the inner retinal surface, allowing the ILM to be stained and therefore distinguished from the unstained retina, allowing its removal.

What doses of TissueBlue are available?

TissueBlue 0.025% is supplied in 2.25 mL pre-filled syringes to which a blunt cannula can be attached for administration during ophthalmic surgery.

Ensure the plunger moves smoothly before injecting the solution. Inject TissueBlue 0.025% directly in a balanced salt solution-filled vitreous cavity. Excess TissueBlue should be removed from the vitreous cavity.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

TissueBlue active ingredients

TissueBlue contains Brilliant Blue G (BBG) Ophthalmic Solution 0.025% for intraocular ophthalmic administration, as the active ingredient.

TissueBlue side effects

The most common side effects of TissueBlue are associated with the surgical procedure, and include:

  • Retinal break, tear, hemorrhage, detachment, and cataracts

In rare instances, TissueBlue can cause more serious adverse effects. These can include:

  • Excessive staining

Your doctor will assess the benefits of using TissueBlue against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of TissueBlue to the FDA. Visit, or call 1-800-FDA-1088.

TissueBlue drug interactions

Other drugs may interact with TissueBlue, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

TissueBlue contraindications

You should not use TissueBlue if you:

  • Are allergic to the active ingredient Brilliant Blue G Ophthalmic Solution
  • Are allergic to any of the other ingredients in TissueBlue (polyethylene glycol and buffered sodium chloride solution)

Talk to your doctor before using TissueBlue if you:

  • Are taking any of the medications that could interact with TissueBlue
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

TissueBlue generic

TissueBlue is the trademark brand name for Brilliant Blue G Ophthalmic Solution manufactured by Dutch Ophthalmic USA Research Centre (DORC). A generic version of Brilliant Blue G Ophthalmic Solution is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find TissueBlue savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.