Uplizna Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Uplizna cost savings if eligible

If you are eligible for the Uplizna patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Uplizna through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Uplizna patient assistance program?

You could receive your Uplizna without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Uplizna patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Uplizna.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Uplizna patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Uplizna medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Uplizna coupon provider?

At NiceRx, we help eligible individuals access the Uplizna patient assistance program. This means that we are not a Uplizna coupon, a Uplizna discount card, or a Uplizna copay card provider. We do not offer any medication trial offers or free Uplizna samples.

Can NiceRx help me get Uplizna cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Uplizna medication, or if you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Uplizna cost without insurance?

Uplizna costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Uplizna intravenous solution (100 mg/10 mL) will typically cost around $138,000 for 30 milliliters. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Uplizna cost with insurance?

The copay of Uplizna will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Uplizna?

Uplizna is an FDA (U.S. Food and Drug Administration) approved medication, developed by Viela Bio, but later acquired by Horizon Therapeutics. Uplizna is a CD19-directed cytolytic antibody used for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adults who are anti-aquaporin-4 (AQP4) antibody positive. NMOSD is a rare autoimmune disease of the central nervous system that mainly affects the optic nerves and spinal cord.

What doses of Uplizna are available?

Uplizna is available as an injection, in the following doses: 100 mg/10 mL (10 mg/mL).

Determine if there is an active infection before each infusion. Hepatitis B virus, (HBV) quantitative serum immunoglobulins, and tuberculosis screening are required before the first dose. Premedicate with a corticosteroid, an antihistamine, and an antipyretic. The recommended initial dose is a 300 mg intravenous infusion followed 2 weeks later by a second 300 mg intravenous infusion.

Please read the prescribing information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Uplizna active ingredients

Uplizna contains inebilizumab-cdon, a monoclonal antibody, as the active ingredient.

Uplizna side effects

The most common side effects of Uplizna in clinical trials compared to placebo include:

  • Urinary tract infection
  • Arthralgia (joint pain)
  • Back pain

In rare instances, Uplizna can cause more serious side effects. These can include:

  • Infusion reactions
  • Recurrent infections
  • May cause fetal harm – females of reproductive potential are advised to use an effective method of contraception during treatment and for 6 months after
  • Progressive Multifocal Leukoencephalopathy (PML)

Your doctor will assess the benefits of using Uplizna against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Uplizna to the FDA. Visit, or call 1-800-FDA-1088.

Uplizna drug interactions

Uplizna can interact with other medications. These include:

  • Concomitant use with immunosuppressant drugs, such as systemic corticosteroids, may increase the risk of infection
  • Vaccination with live-attenuated or live vaccines is not advised during or following treatment, until B-cell repletion

This list is not exhaustive and other prescription drugs may interact with Uplizna.

Uplizna contraindications

You should not use Uplizna if you:

  • Are allergic to the active ingredient inebilizumab-cdon
  • Are allergic to any of the other ingredients in Uplizna
  • Have an active hepatitis B infection
  • Have active or untreated latent tuberculosis
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Uplizna if you:

  • Are taking any of the medications that could interact with Uplizna
  • Have an infection
  • Have taken, or plan to take medicines that affect your immune system
  • Are a carrier of the hepatitis B virus
  • Are breastfeeding or are planning to breastfeed

Uplizna generic

Uplizna is the trademark brand name for inebilizumab-cdon manufactured by Horizon Therapeutics. A generic version of inebilizumab-cdon is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Uplizna savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.