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Vyxeos Patient assistance program

Is your Vyxeos medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Vyxeos medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Vyxeos cost savings if eligible

With our assistance, you could access the Vyxeos patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Vyxeos patient assistance?

We review each Vyxeos enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Vyxeos patient assistance program?

Our process makes it as easy as possible to apply for the Vyxeos patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Vyxeos, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Vyxeos coupons provider?

NiceRx is not a Vyxeos coupon, Vyxeos discount card, or Vyxeos copay card provider. We do not offer Vyxeos manufacturer coupons, Vyxeos discounts, rebates, Vyxeos savings cards, trial offers, or free Vyxeos samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Vyxeos
  • Your insurance company will not pay for your Vyxeos prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Vyxeos cost without insurance?

Without insurance, Vyxeos costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Vyxeos intravenous powder for injection (100 mg-44 mg) will cost around $9,400 for 1 powder for injection.

How much does Vyxeos cost with insurance?

The copay for Vyxeos will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Vyxeos?

Vyxeos is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Jazz Pharmaceuticals. Vyxeos is a liposomal combination of daunorubicin, an anthracycline topoisomerase inhibitor, and cytarabine, a nucleoside metabolic inhibitor. It is indicated for the treatment of adults and pediatric patients 1 year of age and older with certain types of newly-diagnosed therapy-related acute myeloid leukemia (also called therapy-related AML, t-AML) or AML with myelodysplasia-related changes (AML-MRC). AML is a rapidly progressing cancer that forms in the bone marrow and results in an increased number of white blood cells in the bloodstream.

What doses of Vyxeos are available?

Vyxeos is available in injection form, in the following doses: 44 mg daunorubicin and 100 mg cytarabine.

Starting: Vyxeos liposome via intravenous infusion over 90 minutes on days 1, 3, and 5 and on days 1 and 3 for subsequent cycles of induction, if needed. Consolidation: Vyxeos liposome via intravenous infusion over 90 minutes on days 1 and 3.

Vyxeos has different dosage recommendations than daunorubicin hydrochloride injection, cytarabine injection, daunorubicin citrate liposome injection, and cytarabine liposome injection. Verify the drug name and dose prior to preparation and administration to avoid dosing errors. Do not interchange Vyxeos with other daunorubicin or cytarabine-containing products.

Please see the full prescribing information for the complete boxed warning and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Vyxeos active ingredients

The active ingredient of Vyxeos is cytarabine and daunorubicin. Vyxeos is part of a group of medicines called “antineoplastics” used against cancer cells.

Vyxeos side effects

The most common side effects of Vyxeos in clinical trials (incidence ≥ 25%) include:

  • Hemorrhagic events
  • Febrile neutropenia
  • Rash, edema
  • Nausea, vomiting
  • Mucositis
  • Diarrhea, colitis, constipation, abdominal pain, decreased appetite
  • Musculoskeletal pain
  • Tiredness
  • Dyspnea
  • Headache, cough
  • Arrhythmia
  • Pneumonia, bacteremia, chills
  • Sleep disorders

In rare instances, Vyxeos can cause more serious side effects. These can include:

  • Burning, stinging, or blisters and skin sores at the injection site
  • Serious or fatal hemorrhagic events with associated prolonged thrombocytopenia (low platelet count)
  • Cardiotoxicity – Vyxeos treatment is not recommended in patients with cardiac function that is less than normal
  • Severe or life-threatening hypersensitivity reactions
  • Local tissue necrosis at the site of drug extravasation
  • Embryo-fetal toxicity – females of reproductive potential are advised to use effective contraception

Your doctor will assess the benefits of using Vyxeos against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Vyxeos to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Vyxeos drug interactions

Vyxeos can interact with other medications. These include:

  • Cardiotoxic agents
  • Hepatotoxic agents
  • Vaccines

This list is not exhaustive and other prescription drugs may interact with Vyxeos.

Vyxeos contraindications

You should not use Vyxeos if you:

  • Are allergic to the active ingredient cytarabine and daunorubicin
  • Are allergic to any of the other components of the formulation
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Vyxeos if you:

  • Are taking any of the medications that could interact with Vyxeos
  • Have heart disease, including heart failure
  • Have a hepatic or renal impairment
  • Are receiving radiation treatment of your chest area
  • Have Wilson’s disease

Vyxeos generic

Vyxeos is the trademark brand name for cytarabine and daunorubicin manufactured by Jazz Pharmaceuticals. A generic version of cytarabine and daunorubicin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Vyxeos savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.