Wakix Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Wakix cost savings if eligible

If you are eligible to receive your Wakix prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Wakix patient assistance?

To be eligible for the Wakix patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Wakix enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Wakix patient assistance program?

Applying for the Wakix patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Wakix, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Wakix assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Wakix patient assistance program, we will also request your Wakix medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Wakix coupons provider?

NiceRx does not provide Wakix coupons, discount cards, or copay cards. We do not offer printable Wakix manufacturer coupons, Wakix discounts, rebates, Wakix savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Wakix medication with NiceRx.

Can NiceRx help me get Wakix if I have insurance?

NiceRx may be able to help you access Wakix patient assistance if:

  • You have a high copay or coinsurance responsibility for Wakix
  • Your insurance company will not pay for your Wakix prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Wakix cost without insurance?

Wakix prices without insurance will vary by retailer. As a guide, Wakix oral tablet 4.45 mg will typically cost around $3,393 for a supply of 30 tablets.

How much does Wakix cost with insurance?

Your individual healthcare plan will determine the copay of Wakix with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Wakix?

Wakix is an FDA-approved medication manufactured by Harmony Biosciences, LLC for patients above 18 years of age. Wakix is indicated for the treatment of narcolepsy. It is used in the treatment of excessive daytime sleepiness (EDS) or cataplexy in adult patients with narcolepsy. It is the first and only once-daily tablet that is FDA approved to treat EDS or cataplexy in adults with narcolepsy.

Wakix (pitolisant) is a histamine-3 (H3) receptor antagonist/inverse agonist. It increases histamine levels in the brain. The mechanism of action of Wakix in treating EDS or cataplexy in adults with narcolepsy is not fully known or understood. It significantly Reduces EDS Versus placebo.

What doses of Wakix are available?

Wakix is available in a film-coated tablet form, for oral use, and is available in the following doses: 4.45 mg and 17.8 mg.

The recommended dosage range for Wakix is 17.8 mg to 35.6 mg administered orally once daily in the morning upon wakening. Dosage is titrated as follows: Week 1 – Initiate with a dosage of 8.9 mg (two 4.45 mg tablets) once daily; Week 2 – Increase dosage to 17.8 mg (one 17.8 mg tablet) once daily; Week 3 – can increase to the maximum dose of 35.6 mg (two 17.8 mg tablets) once daily. Doses can be adjusted relative to tolerability. It may take up to 8 weeks for some patients to achieve a clinical response.

Dosing is adjusted for patients with moderate hepatic impairment (child-pugh B), mild hepatic impairment (child-pugh A), moderate or severe renal impairment, or in patients who are poor metabolizers of CYP2D6 (these patients have higher concentrations of Wakix than normal CYP2D6 metabolizers). Patients who are poor metabolizers of CYP2D6 tend to have side effects even with a very low drug dose.

Dosage adjustment is also recommended in patients with concomitant use of strong CYP3A4 inducers such as clarithromycin, erythromycin, diltiazem, itraconazole, ketoconazole, ritonavir, verapamil, goldenseal, and grapefruit. CYP3A4 inducers decrease pitolisant exposure by 50%.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition. Wakix is not a controlled substance.

Wakix active ingredients

The active drug in Wakix is pitolisant hydrochloride. It belongs to a group of medications known as histamine-3 blockers.

Wakix side effects

The most common side effects or adverse effects caused by Wakix (which may affect 1 in 10) include:

  • Insomnia (difficulty sleeping)
  • Nausea (feeling sick)
  • Anxiety
  • Vertigo (a spinning sensation)
  • Dyspepsia (heartburn)
  • Vomiting
  • Tremors
  • Anxiety
  • Body aches or pain
  • Burning, numbness, pain, or tingling in all fingers except the smallest finger
  • Chills
  • Decreased appetite
  • Difficulty in moving
  • Dry mouth
  • Ear congestion
  • Fever
  • Headache
  • Loss of voice
  • Muscle or joint pain (musculoskeletal pain)
  • Runny or stuffy nose
  • Seeing, hearing, or feeling things that are not there
  • Sneezing
  • Sore throat
  • Stomach pain or discomfort

In rare instances, Wakix can cause more serious side effects, which should be immediately reported to your healthcare professional. These can include:

  • Changes in behavior
  • Cough
  • Difficulty swallowing
  • Discouragement
  • Feeling sad or empty
  • Dizziness
  • Fast or irregular heartbeat
  • Fainting
  • Hives, itching, skin rash
  • Irritability
  • Lack of appetite
  • Loss of interest or pleasure
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Seizures
  • Thoughts of killing oneself
  • Tightness in the chest
  • Trouble breathing
  • Trouble concentrating
  • Unusual tiredness or weakness

Your doctor will assess the benefits of using Wakix against your risk of side effects.

Patients are encouraged to report negative side effects or adverse reactions of Wakix to the FDA (Food and drug administration). Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Wakix drug interactions

Wakix can interact with other medications. These include:

  • Hormonal contraceptives. Wakix may reduce the effectiveness of hormonal contraceptives. Therefore, an alternative method of effective contraception should be used
  • Paroxetine
  • Fluoxetine
  • Ibupropion
  • Rifampin
  • Carbamazepine
  • Phenytoin
  • Pheniramine maleate
  • Diphenhydramine
  • Promethazine
  • Imipramine
  • Clomipramine
  • Mirtazapine
  • Quinidine
  • Procainamide
  • Disopyramide
  • Amiodarone
  • Sotalol
  • Ziprasidone
  • Chlorpromazine
  • Thioridazine
  • Moxifloxacin
  • Midazolam
  • Cyclosporine

This list is not exhaustive and other drugs may interact with Wakix.

Wakix contraindications

You should not use Wakix if you:

  • Are allergic to the active ingredient Wakix
  • Are allergic to any of the other ingredients in Wakix
  • Are pregnant or are planning to become pregnant
  • Have a severe hepatic impairment
  • Have a history of cardiac arrhythmias

Talk to your doctor before using Wakix if you:

  • Are taking any of the medications that could interact with Wakix
  • Are breastfeeding or are planning to breastfeed
  • Have heart rhythm irregularities
  • Were born with a heart condition
  • Have electrolyte levels in your blood that are too high or too low
  • Are taking any other medications. Wakix has an effect on the electrical activity of the heart which increases the QT interval. Medicines with this effect can lead to disturbances in heart rhythm, which are more likely in patients with risk factors such as certain heart conditions, or when taken in combination with other medicines that affect QT

Wakix is not recommended in patients with end-stage renal disease. Do not use Wakix if you have severe liver disease.

Wakix generic

Wakix is the trademark brand name for pitolisant manufactured by Harmony Biosciences, LLC. A generic version of Wakix is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Wakix savings through NiceRx. Wakix is a registered trademark of Bioprojet Europe, Ltd.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.