Welireg Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Welireg cost savings if eligible

With our assistance, you could access the Welireg patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Welireg patient assistance?

We review each Welireg enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Welireg patient assistance program?

Our process makes it as easy as possible to apply for the Welireg patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Welireg, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Welireg coupon provider?

NiceRx is not a Welireg coupon, Welireg discount card, or Welireg copay card provider. We do not offer Welireg manufacturer coupons, Welireg discounts, rebates, Welireg savings cards, trial offers, or free Welireg samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Welireg cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Welireg
  • Your insurance company will not pay for your Welireg prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Welireg cost without insurance?

Without insurance, Welireg costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Welireg oral tablet 40 mg will cost around $27,800 for 90 tablets.

How much does Welireg cost with insurance?

The copay for Welireg will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Welireg?

Welireg is an FDA (U.S. Food and Drug Administration) approved medication manufactured for Merck & Co., Inc. FDA approval was based on data from an open-label trial in 61 patients with VHL-associated RCC diagnosed based on a VHL germline alteration and with at least one measurable solid tumor localized to the kidney. Enrolled patients had other VHL-associated tumors, including CNS hemangioblastomas and pNET.

Welireg is a hypoxia-inducible factor inhibitor indicated for the treatment of adult patients with von Hippel-Lindau disease (VHL disease) who require therapy for associated renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or pancreatic neuroendocrine tumors (pNET), not requiring immediate surgery.

What doses of Welireg are available?

Welireg is available in tablet form, in the following doses: 40 mg.

The recommended dose of Welireg is 120 mg orally once daily with or without food until disease progression or unacceptable toxicity. Swallow the tablets whole. Do not chew, crush, or split the tablets. If you vomit after taking a dose, do not take an extra dose. Take your next dose at your regular time the next day.

Read the full prescribing information and medication guide and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Welireg active ingredients

The active ingredient of Welireg is belzutifan. It is classed as a hypoxia-inducible factor-2 alpha (HIF-2α) inhibitor.

Welireg side effects

The most common side effects of Welireg in clinical trials include:

  • Decreased hemoglobin
  • Fatigue
  • Increased creatinine
  • Increased glucose
  • Headache, dizziness, nausea

In rare instances, Welireg can cause more serious side effects. These can include:

  • Anemia – withhold treatment until hemoglobin ≥9g/dL, then resume at a reduced dose or discontinue
  • Hypoxia

Your doctor will assess the benefits of using Welireg against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Welireg to the FDA. Visit, or call 1-800-FDA-1088.

Welireg drug interactions

Welireg can interact with other medications. These include:

  • UGT2B17 or CYP2C19 inhibitors – monitor for signs and symptoms of anemia and hypoxia and reduce the dosage of Welireg as recommended

This list is not exhaustive and other prescription drugs may interact with Welireg.

Welireg contraindications

You should not use Welireg if you:

  • Are allergic to the active ingredient belzutifan
  • Are allergic to any of the other ingredients in Welireg
  • Are pregnant or are planning to become pregnant – Embryo-fetal toxicity, and exposure to Welireg during pregnancy can cause embryo-fetal harm. You should use an effective form of non-hormonal contraception during treatment, and for 1 week after your last dose

Talk to your doctor before using Welireg if you:

  • Are taking any of the medications that could interact with Welireg
  • Are breastfeeding or are planning to breastfeed

Welireg generic

Welireg is the trademark brand name for belzutifan manufactured for Merck & Co., Inc. A generic version of belzutifan is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Welireg savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.