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Xhance Patient assistance program

Is your Xhance medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Xhance medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Xhance cost savings if eligible

With our assistance, you could access the Xhance patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Xhance patient assistance?

We review each Xhance enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Xhance patient assistance program?

Our process makes it as easy as possible to apply for the Xhance patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Xhance, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Xhance coupons provider?

NiceRx is not an Xhance coupon, Xhance discount card, or Xhance copay card provider. We do not offer Xhance manufacturer coupons, Xhance discounts, rebates, Xhance savings cards, trial offers, or free Xhance samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Xhance
  • Your insurance company will not pay for your Xhance prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Xhance cost without insurance?

Without insurance, Xhance costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Xhance nasal spray (93 mcg/inh) will cost around $600 for 16 milliliters.

How much does Xhance cost with insurance?

The copay for Xhance will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Xhance?

Xhance is an FDA (U.S. Food and Drug Administration) approved medication manufactured by OptiNose US, Inc. It is a corticosteroid (steroid) indicated for the treatment of nasal polyps in patients 18 years of age or older.

What doses of Xhance are available?

Xhance is available as a nasal spray, in the following doses: 93mcg of fluticasone propionate in each 106-mg spray.

Xhance is for intranasal use only. It is delivered into the nose by actuating the pump spray into one nostril while simultaneously blowing into the mouthpiece of the device. The recommended adult dose is one spray per nostril twice daily to give a total daily dose of 372 mcg. Two sprays in each nasal passage twice daily may also be effective in some patients (total daily dose of 744 mcg).

Please see the full prescribing information, including the instructions for use, always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Xhance active ingredients

The active ingredient of Xhance is fluticasone propionate.

Xhance side effects

The most common side effects of Xhance in clinical trials compared to placebo include:

  • Nosebleeds
  • Nasal septal ulceration
  • Nasopharyngitis
  • Nasal mucosal erythema
  • Nasal mucosal ulcerations
  • Nasal congestion
  • Acute sinusitis
  • Nasal septal erythema
  • Headache
  • Pharyngitis

In rare instances, Xhance can cause more serious side effects. These can include:

  • Severe or ongoing nosebleeds
  • Runny nose, or crusting around your nostrils
  • Redness, sores, or white patches in your mouth or throat
  • Blurred vision, eye pain, or seeing halos around lights
  • Impaired wound healing
  • Tiredness or muscle weakness, feeling light-headed, nausea, vomiting
  • Septal perforation
  • Candida albicans infection
  • Hypersensitivity reactions
  • Immunosuppression – potential increased susceptibility to or worsening of infections
  • Hypercorticism and adrenal suppression
  • Decrease in bone mineral density

Your doctor will assess the benefits of using Xhance against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Xhance to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Xhance drug interactions

Xhance can interact with other medications. These include:

  • Strong cytochrome P450 3A4 inhibitors such as ritonavir, and ketoconazole

This list is not exhaustive and other prescription drugs may interact with Xhance. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Xhance contraindications

You should not use Xhance if you:

  • Are allergic to the active ingredient fluticasone propionate
  • Have had an allergic reaction to any of the other ingredients in Xhance
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Xhance if you:

  • Are taking any of the medications that could interact with Xhance
  • Have hepatic impairment
  • Have sores or ulcers inside your nose
  • Have had an injury or surgery on your nose
  • Have glaucoma or cataracts
  • Have diabetes
  • Have a weak immune system
  • Have any type of bacterial, viral (ocular herpes simplex), parasitic or fungal infection. More serious or even fatal course of chickenpox or measles can occur in susceptible patients
  • Are breastfeeding or are planning to breastfeed

Xhance generic

Xhance is the trademark brand name for fluticasone propionate manufactured by OptiNose US, Inc. A generic version of fluticasone propionate is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Xhance savings through NiceRx.

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.