Home / Medications / Zavesca

Zavesca Patient assistance program

Is your Zavesca medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Zavesca medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
  • Next steps after qualifying
  • Uploading documents and billing
  • SSN & billing information
  • Medication delivery time

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Zavesca cost savings if eligible

With our assistance, you could access the Zavesca patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Zavesca patient assistance?

We review each Zavesca enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zavesca patient assistance program?

Our process makes it as easy as possible to apply for the Zavesca patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Zavesca, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Zavesca coupon provider?

NiceRx is not a Zavesca coupon, Zavesca discount card, or Zavesca copay card provider. We do not offer Zavesca manufacturer coupons, Zavesca discounts, rebates, Zavesca savings cards, trial offers, or free Zavesca samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Zavesca cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Zavesca
  • Your insurance company will not pay for your Zavesca prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Zavesca cost without insurance?

Without insurance, Zavesca costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Zavesca oral capsules 100 mg will cost around $28,250 for 90 capsules.

How much does Zavesca cost with insurance?

The copay for Zavesca will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Zavesca?

Zavesca is an FDA (U.S. Food and Drug Administration) approved medication manufactured for Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company. It is a glucosylceramide synthase inhibitor (the enzyme responsible for the first step in the synthesis of most glycosphingolipids) indicated as monotherapy to treat adult patients with mild to moderate type 1 Gaucher disease for whom enzyme replacement therapy (ERT) is not an option.

Type 1 Gaucher disease is caused by a lack of glucocerebrosidase, the enzyme needed for the breakdown of glycosphingolipid glucosylceramide. Lipids build up in the body and cause symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones.

Zavesca is also used in patients of all ages with Niemann-Pick type-C disease, a potentially fatal disease in which glycosphingolipids build up within cells in the brain and elsewhere in the body. Zavesca is used to treat neurological symptoms which include loss of coordination, problems with eye movements that can lead to vision problems, delayed development, problems swallowing, decreased muscle tone, seizures, and learning difficulties.

What doses of Zavesca are available?

Zavesca is available in capsule form, in the following doses: 100 mg.

The recommended dosage is a 100 mg capsule, three times a day at regular intervals. The dose may be reduced to 100 mg once or twice a day in patients due to tremors or diarrhea. Dosing for patients under the age of 12 years should be adjusted according to body surface area.

Please read the patient information provided with your medication and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Zavesca active ingredients

The active ingredient of Zavesca is miglustat.

Zavesca side effects

The most common side effects of Zavesca in clinical trials (incidence ≥5%) include:

  • Constipation, weight loss, stomach pain, flatulence, nausea, and vomiting
  • Diarrhea can be serious – you may need to make changes to your diet, such as avoiding foods high in carbohydrates
  • Headache, including migraine
  • Tremor, leg cramps, dizziness, weakness
  • Vision problems
  • Thrombocytopenia (reduced platelet count)
  • Muscle cramps, back pain
  • Dry mouth
  • Memory loss, unsteady walking
  • Stomach bloating, abdominal pain not related to food, and menstrual changes

In rare instances, Zavesca can cause more serious side effects. These can include:

  • Peripheral neuropathy – perform baseline and follow-up neurological evaluations at 6-month intervals
  • Tremor or exacerbation of existing tremors

Your doctor will assess the benefits of using Zavesca against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zavesca to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Zavesca drug interactions

Other drugs may interact with Zavesca, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medication including any supplements you are taking.

Zavesca contraindications

You should not use Zavesca if you:

  • Are allergic to the active ingredient miglustat
  • Have known hypersensitivity to any of the other ingredients in Zavesca
  • Are pregnant or are planning to become pregnant – Based on animal data, may cause fetal harm
  • Are breastfeeding or are planning to breastfeed – changes in lactation were seen in animal studies and it is likely to be present in breast milk

Talk to your doctor about your medical conditions before using Zavesca if you:

  • Are taking any of the medications that could interact with Zavesca such as imiglucerase
  • Have stomach problems
  • Have gastrointestinal disease, such as inflammatory bowel disease
  • Have kidney disease
  • Have a condition that causes tremors

Zavesca generic

Zavesca is the trademark brand name for miglustat manufactured for Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company. A generic version of miglustat is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zavesca savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.