Zepzelca Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Zepzelca cost savings if eligible

If you are eligible for the Zepzelca patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Zepzelca prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Zepzelca patient assistance program?

We will review your application to determine whether you are eligible for the Zepzelca patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zepzelca patient assistance program?

We make it as easy as possible to apply for the Zepzelca patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Zepzelca. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Zepzelca assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Zepzelca patient assistance program, and we will automatically request your Zepzelca medication refills for up to 1 year.

Is NiceRx a Zepzelca coupons provider?

We are a service provider that helps eligible individuals access the Zepzelca patient assistance program. That means that we do not offer printable Zepzelca manufacturer coupons, Zepzelca discounts, or free Zepzelca samples. We are not a Zepzelca coupon provider or Zepzelca discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Zepzelca if I have insurance?

We may be able to help you to access Zepzelca patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Zepzelca medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Zepzelca cost without insurance?

Zepzelca’s cost without insurance will vary depending on where you buy it. As a guide, Zepzelca intravenous powder for injection 4 mg costs around $7,200 for 1 powder for injection. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Zepzelca cost with insurance?

The copay for Zepzelcawith insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Zepzelca?

Zepzelca has FDA approval (U.S. Food and Drug Administration) and is a trademark of PharmaMar, S.A. used by Jazz Pharmaceuticals.

Zepzelca is an alkylating drug for the treatment of adult patients with metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. This indication is approved under accelerated approval based on the overall response rate and duration of response.

What doses of Zepzelca are available?

Zepzelca is available in injection form, in the following doses: 4 mg lyophilized powder in a single-dose vial

Zepzelca is given by an intravenous infusion into a vein over 60 minutes. It is usually given every 21 days until disease progression or unacceptable toxicity. You may receive medicines to help prevent nausea and vomiting or to make it less severe.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition. Please see the accompanying full Prescribing Information including Patient Information, and discuss with your doctor.

Zepzelca active ingredients

Zepelca contains lurbinectedin an alkylating drug.

Zepzelca side effects

The most common side effects of Zepzelca in clinical trials include:

  • Leukopenia – low white blood cell count
  • Lymphopenia
  • Tiredness
  • Anemia, neutropenia
  • Increased creatinine, alanine aminotransferase, and glucose
  • Thrombocytopenia
  • Nausea, vomiting, loss of appetite, diarrhea, constipation
  • Musculoskeletal pain
  • Decreased albumin
  • Decreased sodium
  • Decreased magnesiumIn rare instances, Zepzelca can cause more serious side effects. These can include:
  • Myelosuppression – initiate treatment only if baseline neutrophil count is ≥ 1,500 cells/mm3 and platelet count is ≥ 100,000/mm3
  • Hepatotoxicity

Your doctor will assess the benefits of using Zepzelca against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zepzelca to the FDA. Visit, or call 1-800-FDA-1088.

Zepzelca drug interactions

Zepzelca can interact with other medications. These include:

  • Strong or moderate CYP3A inhibitors
  • Strong or moderate CYP3A inducers

This list is not exhaustive and other prescription drugs may interact with Zepzelca.

Zepzelca contraindications

You should not use Zepzelca if you:

  • Are allergic to the active ingredient lurbinectedin
  • Are allergic to any of the other ingredients in Zepzelca
  • Are pregnant or are planning to become pregnant – Zepzelca can harm your unborn baby. Females and males of reproductive potential should use an effective method of contraception

Talk to your doctor before using Zepzelca if you:

  • Are taking any of the medications that could interact with Zepzelca
  • Are breastfeeding or are planning to breastfeed – do not breastfeed during treatment, and for 2 weeks after your final dose
  • Have liver or kidney problems

Zepzelca generic

Zepzelca is the trademark brand name for lurbinectedin manufactured by Jazz Pharmaceuticals. A generic version of lurbinectedin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zepzelca savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.