Zokinvy Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Zokinvy cost savings if eligible

If you are eligible for the Zokinvy patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Zokinvy prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Zokinvy patient assistance program?

We will review your application to determine whether you are eligible for the Zokinvy patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zokinvy patient assistance program?

We make it as easy as possible to apply for the Zokinvy patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Zokinvy. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Zokinvy assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Zokinvy patient assistance program, and we will automatically request your Zokinvy medication refills for up to 1 year.

Is NiceRx a Zokinvy coupon provider?

We are a service provider that helps eligible individuals access the Zokinvy patient assistance program. That means that we do not offer printable Zokinvy manufacturer coupons, Zokinvy discounts, or free Zokinvy samples. We are not a Zokinvy coupon provider or Zokinvy discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Zokinvy cheaper if I have insurance?

We may be able to help you to access Zokinvy patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Zokinvy medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Zokinvy cost without insurance?

Zokinvy cost without insurance will vary depending on where you buy it. As a guide, Zokinvy oral capsules 50 mg usually cost $23,600 for 30 capsules. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Zokinvy cost with insurance?

The copay for Zokinvy with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Zokinvy?

Zokinvy is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Eiger BioPharmaceuticals Inc. It is classed as a farnesyltransferase inhibitor and used in patients 12 months of age and older with a body surface area (BSA) of 0.39 m2 and above:

  • To reduce the risk of mortality in Hutchinson-Gilford Progeria Syndrome (HGPS)
  • For treatment of processing-deficient Progeroid Laminopathies with either Heterozygous LMNA mutation with progerin-like protein accumulation, or Homozygous or compound heterozygous ZMPSTE24 mutations

Zokinvy has certain limitations of use and is not recommended for other Progeroid Syndromes or processing-proficient Progeroid Laminopathies.

What doses of Zokinvy are available?

Zokinvy is available in capsule form, in the following doses: 50 mg and 75 mg.

The initial dose is 115 mg/m2 twice daily with morning and evening meals. Increase the dose to 150 mg/m2 twice daily after 4 months and round the total daily dose to the nearest 25 mg increment. Swallow the capsules whole. If you are unable to swallow capsules, mix the contents of the capsule with Ora Blend SF, Ora-Plus, orange juice, or applesauce. If you miss a dose take the missed dose as soon as you can, but skip the missed dose if your next scheduled dose is due in less than 8 hours.

Read the full instructions for use and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Zokinvy active ingredients

Zokinvy contains lonafarnib as the active ingredient.

Zokinvy side effects

The most common side effects of Zokinvy in clinical trials include:

  • Vomiting, nausea, headache, fatigue
  • Upper respiratory tract infection
  • Abdominal pain, weight loss, diarrhea, decreased appetite
  • Musculoskeletal pain
  • Electrolyte abnormalities
  • Myelosuppression
  • Increased aspartate aminotransferase, increased alanine aminotransferase, decreased blood bicarbonate
  • Hypertension (high blood pressure)

In rare instances, Zokinvy can cause more serious side effects. These can include:

  • Nephrotoxicity
  • Retinal toxicity
  • Impaired fertility
  • Embryo-fetal toxicity – females of reproductive potential are advised to use effective contraception

Your doctor will assess the benefits of using Zokinvy against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zokinvy to the FDA. Visit, or call 1-800-FDA-1088.

Zokinvy drug interactions

Zokinvy can interact with other medications. These include:

  • Strong or moderate CYP3A inhibitors or inducers
  • Midazolam
  • St. John’s wort
  • Antibiotics
  • Antifungals
  • Antivirals to treat HIV or hepatitis C
  • Cholesterol medicine – atorvastatin, lovastatin, or simvastatin
  • Heart or blood pressure treatment
  • Treatments for seizures
  • Grapefruit, grapefruit juice, or Seville oranges

This list is not exhaustive and other prescription drugs may interact with Zokinvy. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Zokinvy contraindications

You should not use Zokinvy if you:

  • Are allergic to the active ingredient lonafarnib
  • Are allergic to any of the other ingredients in Zokinvy
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Zokinvy if you:

  • Are taking any of the medications that could interact with Zokinvy
  • Have kidney disease
  • Have eye problems
  • Are breastfeeding or are planning to breastfeed

Zokinvy generic

Zokinvy is the trademark brand name for lonafarnib manufactured by Eiger BioPharmaceuticals Inc. A generic version of lonafarnib is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zokinvy savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.