Zynlonta Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Zynlonta cost savings if eligible

The Zynlonta patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Zynlonta, regardless of the retail price.

Am I eligible for the Zynlonta patient assistance program?

To find out if you are eligible for Zynlonta assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zynlonta patient assistance program?

Our application process aims to make it as easy as possible to apply for the Zynlonta patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Zynlonta.

NiceRx will review your application and determine whether you may be eligible for Zynlonta assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Zynlonta patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Zynlonta.

Is NiceRx a Zynlonta coupons provider?

NiceRx is a service provider that helps eligible individuals access the Zynlonta patient assistance program. We do not offer trial offers or free Zynlonta samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Zynlonta coupons, discount cards, or Zynlonta copay cards.

Can NiceRx help me get Zynlonta if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Zynlonta medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Zynlonta cost without insurance?

Zynlonta prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Zynlonta intravenous injection of 10 mg typically costs $24,550 for 1 injection.

How much does Zynlonta cost with insurance?

The copay for Zynlonta will vary by the terms of your healthcare plan. To find out what you might need to pay for Zynlonta with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Zynlonta?

Zynlonta is an FDA (U.S. Food and Drug Administration) approved medication manufactured by ADC Therapeutics SA. Zynlonta is a CD19-directed antibody-drug conjugate (ADC), indicated for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, DLBCL arising from low-grade lymphoma, and high-grade B-cell lymphoma. This indication is approved under accelerated approval based on the overall response rate.

What doses of Zynlonta are available?

Zynlonta is available in injection form, in the following doses: 10 mg of loncastuximab tesirine-lpyl as a lyophilized powder in a single-dose vial for reconstitution and further dilution.

Zynlonta is given as an intravenous infusion over 30 minutes on Day 1 of each cycle, every 3 weeks. The recommended dosage is 0.15 mg/kg every 3 weeks for 2 cycles. 0.075 mg/kg every 3 weeks for the following cycles.

Premedicate with dexamethasone 4 mg orally, or intravenously twice daily for 3 days, starting the day before Zynlonta treatment starts. See the full prescribing information for instructions on preparation and administration.

Always speak with your healthcare provider for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Zynlonta active ingredients

Zynlonta contains the active ingredient loncastuximab tesirine-lpyl.

Zynlonta side effects

The most common side effects of Zynlonta in clinical trials include:

  • Thrombocytopenia (reduced platelets)
  • Increased gamma-glutamyltransferase
  • Neutropenia, anemia, hyperglycemia
  • Transaminase elevation
  • Hypoalbuminemia
  • Fatigue
  • Rash, edema, nausea
  • Musculoskeletal pain

In rare instances, Zynlonta can cause more serious adverse reactions. These can include:

  • Pleural effusion, pericardial effusion, ascites, peripheral edema, and general edema
  • Myelosuppression
  • Infections
  • Cutaneous reactions
  • Embryo-fetal toxicity

Your doctor will assess the benefits of using Zynlonta against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zynlonta to the FDA. Visit, or call 1-800-FDA-1088.

Zynlonta drug interactions

There is currently no data for Zynlonta interactions with other medications. However, other drugs may affect loncastuximab tesirine-lpyl, including prescription and over-the-counter medicines, vitamins, and herbal products.

Zynlonta contraindications

You should not use Zynlonta if you:

  • Are allergic to the active ingredient loncastuximab tesirine-lpyl
  • Are allergic to any of the other ingredients in Zynlonta
  • Are pregnant or are planning to become pregnant – use effective birth control during treatment and for 9 months after the last dose
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Zynlonta if you:

  • Are taking any of the medications that could interact with Zynlonta

Zynlonta generic

Zynlonta is the trademark brand name for loncastuximab tesirine-lpyl manufactured by ADC Therapeutics SA. A generic version of loncastuximab tesirine-lpyl is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zynlonta savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.