Amvuttra Coupon & Prices

Is your Amvuttra medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Amvuttra medication with our help.

Get Started Now
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Amvuttra cost savings if eligible

The Amvuttra patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Amvuttra, regardless of the retail price.

Am I eligible for the Amvuttra patient assistance program?

To find out if you are eligible for Amvuttra assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Amvuttra patient assistance program?

Our application process aims to make it as easy as possible to apply for the Amvuttra patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Amvuttra.

NiceRx will review your application and determine whether you may be eligible for Amvuttra assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Amvuttra patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Amvuttra.

Is NiceRx an Amvuttra coupon provider?

NiceRx is a service provider that helps eligible individuals access the Amvuttra patient assistance program. We do not offer trial offers or free Amvuttra samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Amvuttra coupons, discount cards, or Amvuttra copay cards.

Can NiceRx help me get Amvuttra cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Amvuttra medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Amvuttra cost without insurance?

Amvuttra prices without insurance will vary depending on how much you buy. Prices will also vary by retailer.

How much does Amvuttra cost with insurance?

The copay for Amvuttra will vary by the terms of your healthcare plan. To find out what you might need to pay for Amvuttra with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Amvuttra?

Amvuttra is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Alnylam Pharmaceuticals, Inc. Amvuttra is a transthyretin-directed small interfering RNA for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) in adults. Hereditary ATTR amyloidosis is an aggressive, debilitating, and often fatal disease.

Extensive data supporting treatment with Amvuttra in patients with hATTR polyneuropathy shows the drug’s ability to improve neuropathy impairment and create significant improvements in the quality of life, functional status, and performance in patients. This builds on the effectiveness of patisiran, which was the first siRNA therapy approved for any disease.

FDA approval for Amvuttra is based on results from the HELIOS-A Phase III study in which patients on the RNAi therapeutic met all secondary endpoints at 18 months. The ongoing HELIOS-B study is investigating vutrisiran for ATTR patients with cardiomyopathy.

What doses of Amvuttra are available?

Amvuttra is available as an injection, in the following doses: 25 mg/0.5 mL in a single-dose prefilled syringe.

Amvuttra 25 mg is administered by subcutaneous injection once every 3 months. Please see the full prescribing information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Amvuttra active ingredients

Amvuttra contains vutrisiran as the active ingredient. It is classed as a gene-silencer, that inhibits the production of the transthyretin (TTR) protein in the liver, therefore reducing levels of TTR protein in the body, and preventing organ damage.

Amvuttra side effects

The most common side effects of Amvuttra in clinical trials compared to the placebo group include:

  • Arthralgia (joint pain)
  • Dyspnea
  • Shortness of breath
  • Injection site reactions

In rare instances, Amvuttra can cause more serious side effects. These can include:

  • Reduced serum vitamin A levels can affect vision. If you have problems with your vision such as night blindness consult your doctor

Your doctor will assess the benefits of using Amvuttra against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Amvuttra to the FDA. Visit, or call 1-800-FDA-1088.

Amvuttra drug interactions

Other drugs may interact with Amvuttra, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

Amvuttra contraindications

You should not use Amvuttra if you:

  • Are allergic to the active ingredient vutrisiran
  • Are allergic to any of the other ingredients in Amvuttra

Talk to your doctor before using Amvuttra if you:

  • Are taking any of the medications that could interact with Amvuttra
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Amvuttra generic

Amvuttra is the trademark brand name for vutrisiran manufactured by Alnylam Pharmaceuticals, Inc. A generic version of vutrisiran is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Amvuttra savings through NiceRx.

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.