Apretude Coupon & Prices

Is your Apretude medication too expensive?

Get notified when Apretude medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Your monthly Apretude cost savings if eligible

If you are eligible to receive your Apretude prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Apretude patient assistance?

To be eligible for the Apretude patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Apretude enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Apretude patient assistance program?

Applying for the Apretude patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Apretude, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Apretude assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Apretude patient assistance program, we will also request your Apretude medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx an Apretude coupon provider?

NiceRx does not provide Apretude coupons, discount cards or copay cards. We do not offer printable Apretude manufacturer coupons, Apretude discounts, rebates, Apretude savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Apretude medication with NiceRx.

Can NiceRx help me get Apretude cheaper if I have insurance?

NiceRx may be able to help you access Apretude patient assistance if:

  • You have a high copay or coinsurance responsibility for Apretude
  • Your insurance company will not pay for your Apretude prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Apretude cost without insurance?

Apretude prices without insurance will vary by retailer. As a guide, Apretude intramuscular suspension, extended-release (600 mg/3 mL) will typically cost around $3,900 for 3 milliliters.

How much does Apretude cost with insurance?

Your individual healthcare plan will determine the copay of Apretude with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Apretude?

Apretude is an FDA (U.S. Food and Drug Administration) approved medication manufactured by ViiV Healthcare. It is an HIV-1 integrase strand transfer inhibitor (INSTI) used in at-risk adults and adolescents weighing at least 35 kg for PrEP for HIV prevention. Patients must have had a negative HIV-1 test before starting treatment (with or without an oral lead-in with oral cabotegravir) for HIV-1 PrEP.

FDA approval for Apretude as a PrEP option is based on two clinical trials, HPTN 083 and HPTN 084, which determined the safety and efficacy of cabotegravir long-acting for PrEP in HIV-negative men who have sex with men, transgender women, and cisgender women, who were at increased risk of sexually acquiring HIV. These trials were stopped early after cabotegravir long-acting for PrEP was shown to be more effective than daily oral emtricitabine/tenofovir disoproxil fumarate tablets in preventing HIV.

Patients must be tested for HIV-1 infection before starting treatment and after each injection of Apretude as drug-resistant HIV-1 variants have been found when Apretude has been used for HIV-1 PrEP (pre-exposure prophylaxis) in patients with undiagnosed HIV-1 infection. Apretude treatment should not be started unless a patient tests negative for HIV-1 infection. Patients who do become infected with HIV-1 while receiving Apretude treatment for PrEP must move to a complete HIV-1 treatment plan.

What doses of Apretude are available?

Apretude is available in injection form in single-dose vials, in the following doses: 600 mg/3 mL (200 mg/mL) of cabotegravir extended-release injectable suspension.

You must be tested for HIV-1 infection immediately before initiating treatment for HIV-1 PrEP and before each injection while taking Apretude. An oral lead-in dosing may be used for approximately 1 month with the recommended dosage to assess your tolerability to this drug.

Apretude is for gluteal intramuscular injection only. Start with a single 600-mg (3-mL) injection given 1 month apart for 2 consecutive months, on the last day of an oral lead-in if used, or within 3 days. Continue the injections every 2 months thereafter.

Please see the full prescribing information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Apretude active ingredients

Apretude contains cabotegravir as the active ingredient.

Apretude side effects

The most common side effects of Apretude in clinical trials include:

  • Injection site reactions
  • Diarrhea
  • Headache
  • Pyrexia
  • Tiredness, sleep disorders, somnolence
  • Nausea, dizziness
  • Flatulence, abdominal pain, vomiting, decreased appetite
  • Myalgia, back pain
  • Rash
  • Upper respiratory tract infection

In rare instances, Apretude can cause more serious adverse effects. These can include:

  • Risk of developing resistance to Apretude if you are infected with HIV-1 either before or while receiving treatment
  • Hypersensitivity reactions in association with other integrase inhibitors
  • Hepatotoxicity
  • Depressive disorders

Your doctor will assess the benefits of using Apretude against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Apretude to the FDA. Visit, or call 1-800-FDA-1088.

Apretude drug interactions

Apretude can interact with other medications. These include:

  • Drugs that induce uridine diphosphate glucuronosyltransferase (UGT1A1)
  • Rifamycins such as rifampin and rifabutin
  • Certain drugs used to treat seizures such as carbamazepine, phenobarbital, phenytoin

This list is not exhaustive and other prescription drugs may interact with Apretude.

Apretude contraindications

You should not use Apretude if you:

  • Are allergic to the active ingredient cabotegravir
  • Are allergic to any of the other ingredients in Apretude
  • Are HIV-1 positive

Talk to your doctor before using Apretude if you:

  • Are taking any of the medications that could interact with Apretude
  • Have liver problems
  • Have ever had mental health problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Apretude generic

Apretude is the trademark brand name for cabotegravir manufactured by ViiV Healthcare. A generic version of cabotegravir is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Apretude savings through NiceRx.

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.