Ayvakit Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Ayvakit cost savings if eligible

If you are eligible for the Ayvakit patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Ayvakit prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Ayvakit patient assistance program?

We will review your application to determine whether you are eligible for the Ayvakit patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Ayvakit patient assistance program?

We make it as easy as possible to apply for the Ayvakit patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Ayvakit. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Ayvakit assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Ayvakit patient assistance program, and we will automatically request your Ayvakit medication refills for up to 1 year.

Is NiceRx an Ayvakit coupons provider?

We are a service provider that helps eligible individuals access the Ayvakit patient assistance program. That means that we do not offer printable Ayvakit manufacturer coupons, Ayvakit discounts, or free Ayvakit samples. We are not an Ayvakit coupon provider or Ayvakit discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Ayvakit if I have insurance?

We may be able to help you to access Ayvakit patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Ayvakit medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Ayvakit cost without insurance?

Ayvakit cost without insurance will vary depending on where you buy it. As a guide, Ayvakit oral tablets 100 mg usually cost $35,000 for 30 tablets. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Ayvakit cost with insurance?

The copay for Ayvakit with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Ayvakit?

Ayvakit is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Blueprint Medicines Corporation. Ayvakit is a tyrosine kinase inhibitor used to treat:

  • Adult patients with unresectable or metastatic gastrointestinal stromal tumor (GIST) harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations
  • Advanced systemic mastocytosis (AdvSM), including aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL)

AdvSM is a rare hematologic disorder caused in most cases by the KIT D816V mutation. Ayvakit is not recommended for the treatment of AdvSM in people with low platelet counts.

What doses of Ayvakit are available?

Ayvakit is available in tablet form, in the following doses: 100 mg, 200 mg, and 300 mg.

Patients are selected for treatment based on the presence of a PDGFRA exon 18 mutations. The recommended dose is 300 mg orally once daily on an empty stomach. Take Ayvakit at least one hour before and two hours after a meal.

Please see the full prescribing information and patient information for Ayvakit, and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Ayvakit active ingredients

Ayvakit contains the active ingredient avapritinib, a targeted therapy.

Ayvakit side effects

The most common adverse reactions of Ayvakit in clinical trials include:

  • Edema
  • Nausea, vomiting
  • Tiredness, asthenia
  • Decreased appetite, diarrhea, constipation, abdominal pain
  • Changes in hair color
  • Increased lacrimation
  • Rash

In rare instances, Ayvakit can cause more serious side effects. These can include:

  • Intracranial hemorrhage
  • Central nervous system effects – cognitive impairment, dizziness, sleep disorders, mood disorders, speech disorders, and hallucinations
  • Embryo-fetal toxicity
  • Severe hepatic impairment

Your doctor will assess the benefits of using Ayvakit against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Ayvakit to the FDA. Visit, or call 1-800-FDA-1088.

Ayvakit drug interactions

Ayvakit can interact with other medications. These include:

  • Strong and moderate CYP3A inhibitors – consider a reduction of the dose of Ayvakit if coadministration can not be avoided
  • Strong and moderate CYP3A inducers

This list is not exhaustive and other prescription drugs may interact with Ayvakit. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Ayvakit contraindications

You should not use Ayvakit if you:

  • Are allergic to the active ingredient avapritinib
  • Are allergic to any of the other ingredients in Ayvakit
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Ayvakit if you:

  • Are taking any of the medications that could interact with Ayvakit
  • Are a pregnant woman or are planning to become pregnant – Females and males of reproductive potential should use effective contraception during and for 6 weeks after the final dose
  • Are breastfeeding or are planning to breastfeed

Ayvakit generic

Ayvakit is the trademark brand name for avapritinib manufactured by Blueprint Medicines Corporation. A generic version of avapritinib is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Ayvakit savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.