Epipen Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Epipen cost savings if eligible

If you are eligible for the Epipen patient assistance program, the cost of your medication will be free. We only charge $49 a month, per medication, to cover our service fees. You could receive your Epipen prescription for just $49 a month, regardless of the retail price of your medication.

Strength Avg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
0.3mg/0.3ml 2 count$465.00$49.00$416.00

Am I eligible for the Epipen patient assistance program?

We will review your application to determine whether you are eligible for the Epipen patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Epipen patient assistance program?

We make it as easy as possible to apply for the Epipen patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Epipen. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Epipen assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Epipen patient assistance program, and we will automatically request your Epipen medication refills for up to 1 year.

Is NiceRx an Epipen coupons provider?

We are a service provider that helps eligible individuals access the Epipen patient assistance program. That means that we do not offer printable Epipen manufacturer coupons, Epipen discounts, or free Epipen samples. We are not an Epipen coupon provider or Epipen discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Epipen if I have insurance?

We may be able to help you to access Epipen patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Epipen medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much is Epipen with insurance?

The cost of Epipen with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

How much does Epipen cost without insurance?

Epipen prices without insurance will vary depending on where you buy it. As a guide, Epipen usually costs $700  for 2 auto-injectors. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

What is Epipen?

Epipen is a pre-filled auto-injector containing epinephrine, used for the treatment of life-threatening emergencies such as anaphylaxis in people who are at risk of or have a history of serious life-threatening allergic emergencies. Allergic reactions can be caused by insect bites or stings, foods, drugs, and any other allergens. Epinephrine can also be used to treat exercise-induced anaphylaxis.

EpiPen may be used for self-injection by a person with a history of severe allergic reactions.

Epipen active ingredients

Epinephrine is a hormone produced naturally in your body by your adrenal glands as well as the medulla oblongata. It is classed as an alpha and a beta-receptor agonist or more simply as a stimulant.

Epinephrine helps to narrow your blood vessels and open the airways in your lungs. This effect reverses severe low blood pressure, wheezing, severe skin itching, and other symptoms of an allergic reaction.

Epipen side effects

The most common side effect caused by Epipen include:

  • Difficulty sleeping

Some side effects may go away during treatment as your body adjusts to the medicine. Epipen can cause more serious side effects. These include:

  • Headache, nausea, vomiting
  • Blurred vision, dizziness, sweating, fast heart rate, pounding in the ears
  • Seizures
  • Difficulty speaking, confusion, tremors
  • Pain in the chest, arms, back, jaw, or neck
  • Nervousness

Epipen drug interactions

Epipen can interact with other medications. This can change how Epipen and the other medications work and can make some side effects more likely. Tell your prescribing doctor about all drugs you are taking, particularly:

  • Digoxin
  • Levothyroxine
  • Antidepressants – amitriptyline, doxepin, imipramine, nortriptyline, trimipramine
  • Beta-blockers – carvedilol, labetalol, nadolol, propranolol, sotalol, timolol
  • Ergot medicine – ergotamine, dihydroergotamine
  • MAO inhibitors – phenelzine, rasagiline, tranylcypromine
  • Diabetic medication – empagliflozin, glipizide, insulin, metformin

Epipen warning and precautions

Epipen is not suitable for everyone. Do not use Epipen if you:

  • Are allergic to the active ingredients epinephrine
  • Are allergic to any of the other ingredients in Epipen (you can find these listed in the leaflet which comes with the medication)

Talk to your doctor before using Epipen if you:

  • Have heart disease or high blood pressure
  • Have asthma
  • Have depression or a mental illness
  • Have a thyroid disorder
  • Have asthma
  • Have diabetes

Having an allergic reaction while pregnant or breastfeeding could harm both the mother and baby. If you need to use an EpiPen during pregnancy or while you are breastfeeding seek medical attention immediately. Make sure your doctor caring for you during pregnancy or when you are breastfeeding knows you have used an Epipen.

Seek emergency medical attention even after you have used EpiPen. The effects may wear off after 10 or 20 minutes. You will need to be monitored and receive further medical treatment.

The EpiPen Auto-Injector (0.3 mg) is for patients who weigh 66 pounds (30 kilograms) or more.

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.