Esbriet Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Esbriet cost savings if eligible

If you are eligible for the Esbriet patient assistance program you can get your medication for free. Our monthly flat rate of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Esbriet through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
100mg 60 capsules$10,335.00$49.00$10,286.00
150mg 60 capsules$10,765.00$49.00$10,716.00

Am I eligible for the Esbriet patient assistance program?

You could receive your Esbriet without paying the full retail price if you meet the eligibility criteria for assistance. This criteria is set by the pharmaceutical companies who are providing assistance programs. At NiceRx we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Esbriet patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Esbriet.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Esbriet patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Esbriet medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx an Esbriet coupons provider?

At NiceRx, we help eligible individuals access the Esbriet patient assistance program. This means that we are not an Esbriet coupon, an Esbriet discount card, or an Esbriet copay card provider. We do not offer any medication trial offers, or free Esbriet samples.

Can NiceRx help me get Esbriet if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Esbriet medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much is Esbriet with insurance?

The cost of Esbriet will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

How much does Esbriet cost without insurance?

Esbriet costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Esbriet will typically cost around $10,600 for 60 capsules. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

What is Esbriet?

Esbriet contains the prescription medicine pirfenidone, used for the treatment of idiopathic pulmonary fibrosis (IPF), a lung disease. IPF is a condition where scar tissue is formed deep within the lungs. This scar tissue over time becomes thicker and more rigid making it more difficult for the lungs to work properly and harder for you to breathe. The lack of oxygen caused by this affects how other organs function in your body causing other medical complications. Exactly what causes IPF is not known, but the disease is progressive and can be life-threatening.

Esbriet will slow the progression of the disease but will not cure IPF.

Esbriet active ingredients

Pirfenidone is in a class of medications called pyridones. Pirfenidone’s mechanism of action is thought to be through reducing lung scarring, by reducing the production of growth factors and procollagens I and II. (Procollagens are used to produce collagen, a protein that normally adds strength and support to many body tissues). However, the exact mechanism for the action of pirfenidone in the treatment of IPF is not fully understood.

Esbriet is started on a dose of one capsule or tablet a day on the first week of treatment. It is gradually increased weekly by one tablet or capsule a week until you are taking one capsule or tablet three times a day. Esbriet is taken with food.

Esbriet side effects

The most common side effects caused by Esbriet include:

  • Nausea, vomiting, diarrhea, heartburn, stomach pain, loss of appetite, weight loss
  • Tiredness, headaches, dizziness
  • Joint pain
  • Skin sensitivity to light, rash
  • Stuffy nose, sore throat, sneezing
  • Insomnia (trouble sleeping)

In rare instances, Esbriet can cause more serious side effects. These can include:

  • Severe stomach pains, vomiting, diarrhea
  • Pain or burning in the throat
  • Liver problems – yellow color to eyes or skin (jaundice), darker stools and urine, tiredness, easily bruised

Your doctor will assess the benefits of using Esbriet against your risk of side effects.

Esbriet drug interactions

Esbriet can interact with other medications. These include:

  • Treatment for irregular heartbeats – amiodarone
  • Antibiotic treatment – ciprofloxacin, enoxacin
  • Treatment for cancer – capmatinib, pexidartinib, rucaparib, vemurafenib
  • Antidepressants – fluvoxamine
  • Immunosuppressive medication – leflunomide, teriflunomide
  • Treatment for high cholesterol – lomitapide, mipomersen
  • Treatment for hypertension and chronic angina pectoris – mibefradil
  • Medication for Cushing’s disease – osilodrostat

This list is not exhaustive and other drugs may interact with Esbriet.

Esbriet warning and precautions

You should not use Esbriet if you:

  • Are allergic to the active ingredient pirfenidone
  • Are allergic to any of the other ingredients in Esbriet

Talk to your doctor before using Esbriet if you:

  • Are taking any of the medications that could interact with Esbriet
  • Have liver disease
  • Have kidney disease
  • Smoke
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.