Letairis Coupon & Prices

Is your Letairis medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Letairis medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Have you been prescribed Letairis and need help paying for your medication? With our help, you may be able to get your essential medicine for just $49 per month*.

NiceRx works directly with your healthcare provider to help you enroll in assistance programs for prescription medications. All stages of the application process are handled by us on your behalf, helping you to secure easy and affordable access to the medications you need.

Your monthly Letairis cost savings if eligible

If you are eligible for the Letairis patient assistance program, you could receive your medication for a flat fee of $49 per month. You could save:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
5mg 30 tablets$10,440.00$49.00$10,391.00
10mg 30 tablets$10,440.00$49.00$10,391.00

Am I eligible for the Letairis patient assistance program?

At NiceRx we will review your potential eligibility for the Letairis patient assistance program. We review each Letairis application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Letairis patient assistance program? 

Our application process is simple and straightforward, making it as easy as possible to apply for the Letairis patient assistance program. Begin by completing your enrollment application on our website. You will need to tell us about any medications you’re taking, including Letairis. We’ll also ask for details about your healthcare provider, your insurance plan, and your household income. 

Once we have reviewed the details of your application we will determine if you may be eligible for Letairis assistance. If you are eligible we’ll handle the full application process for you. Once enrolled in the Letairis patient assistance program, we’ll also request your Letairis medication refills on your behalf for up to one year.

Is NiceRx a Letairis coupons provider?

NiceRx is a service provider that helps eligible individuals access the Letairis patient assistance program. We are not a Letairis coupon, a Letairis discount card, or a Letairis copay card provider. We don’t offer printable Letairis manufacturer coupons, Letairis discounts, rebates, Letairis savings cards, trial offers, or free Letairis samples. If you’re looking for coupons for Letairis or cheap Letairis, you will likely save more by applying for the patient assistance program with NiceRx. 

Can NiceRx help me get Letairis if I have insurance? 

Eligibility for the patient assistance program will depend on a range of factors. You may be eligible if you have insurance and your insurance company won’t pay for your Letairis medication, or you have a high copay or coinsurance responsibility. We may even be able to help if you don’t have insurance or your Medicare plan doesn’t cover Letairis.

Apply online to find out more.

How much is Letairis with insurance?

The cost of Letairis will depend on the terms of your healthcare plan. To find out exactly what you would need to pay for Letairis, your insurance provider or pharmacist will be able to calculate your copay with your insurance.

How much does Letairis cost without insurance?

Letairis prices without insurance will vary depending on the amount you buy, and where you buy it from. As a guide, a bottle of 30 Letairis tablets, at either 5 mg or 10 mg, will cost around $10,000.

What is Letairis?

Letairis is prescribed to adults to treat pulmonary arterial hypertension (PAH), high blood pressure in the vessels inside your lungs.

PAH can interfere with how much oxygen you absorb into your blood. With PAH, the vessels and arteries in your lungs can narrow, become blocked, and damaged. This increases your blood pressure in your lungs and reduces how much oxygen you can take into your blood. When you have PAH, it can make you feel short of breath, cause chest pain, fatigue, heart palpitations, and fainting. It can also make it harder for you to exercise. 

Letairis helps to relax the muscle tissue in the arteries and blood vessels inside your lungs. This can improve blood flow and reduce blood pressure, providing relief from your PAH symptoms. Letairis can slow down the worsening of your PAH, and it can improve your ability to exercise.

Letairis active ingredients

The active ingredient in Letairis is called ambrisentan. It opens up the arteries and vessels in your lungs to help reduce blood pressure and improve blood flow. Muscle tissue in your arteries and blood vessels can constrict and tighten, reducing the flow of blood and increasing blood pressure. This happens when your body releases a substance called endothelin. Endothelin attaches to areas on the surface of the muscle called endothelin receptors. This stimulates the receptors and causes the muscle to constrict.

Ambrisentan works by stopping this from happening. When you take Letairis, the ambrisentan molecules it contains attach to these endothelin receptors, blocking them. This means endothelin can’t bind with and stimulate the receptors. This stops your blood vessels from becoming constricted, improving blood flow.

Letairis side effects & Letairis drug interactions

The most common side effects caused by Letairis include:

  • A stuffy nose (nasal congestion)
  • Inflamed nasal passages (sinusitis)
  • Swelling of your hands, legs, ankles, or feet (peripheral edema)
  • Hot flushes
  • Headaches (when taken with tadalafil)
  • A cough (when taken with tadalafil)
  • Indigestion (when taken with tadalafil)
  • Bronchitis (when taken with tadalafil)

In rare instances, Letairis can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • Serious birth defects if taken during pregnancy 
  • Swelling all over your body caused by fluid retention
  • A decreased sperm count
  • Anemia (low red blood cell count) can happen during the few weeks of taking Letairis. In severe cases, it may require a blood transfusion 
  • Liver damage

Your doctor will assess your risk of side effects against the benefits of taking Letairis.

When you take Letairis with other medications, they can interact which may potentially change how Letairis and the other medications work. In some instances, certain side effects can become more likely and more severe. It is known to interact with the following: 

  • Any other medications taken to treat pulmonary arterial hypertension 
  • Cyclosporine, an immunosuppressant medication usually taken to treat inflammatory diseases
  • Rifampicin, an antibiotic used to treat a range of infections

Letairis warnings & precautions

Letairis can cause serious birth defects if you take it during pregnancy. You should never take Letairis when you’re pregnant, and you must make sure you don’t become pregnant while taking it. You should use two forms of effective birth control while taking Letairis. Talk to your physician about birth control and about pregnancy testing while taking Letairis.

Letairis isn’t suitable for everyone. Don’t take Letairis if you:

  • Are allergic to the active ingredient ambrisentan
  • Are allergic to any of the other ingredients in Letairis 
  • Are pregnant or are planning to become pregnant
  • Have idiopathic pulmonary fibrosis (IPF) – a chronic lung-scarring disease
  • Are under 18 years of age

Talk to your doctor before taking Letairis if you:

  • Are taking any of the medications that could interact with Letairis (see the section above)
  • Have anemia (a low blood cell count)
  • Have any liver problems
  • Are breastfeeding or are planning to breastfeed

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.