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Pemfexy Patient assistance program

Is your Pemfexy medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Pemfexy medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Pemfexy cost savings if eligible

With our assistance, you could access the Pemfexy patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Pemfexy patient assistance?

We review each Pemfexy enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Pemfexy patient assistance program?

Our process makes it as easy as possible to apply for the Pemfexy patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Pemfexy, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Pemfexy coupon provider?

NiceRx is not a Pemfexy coupon, Pemfexy discount card, or Pemfexy copay card provider. We do not offer Pemfexy manufacturer coupons, Pemfexy discounts, rebates, Pemfexy savings cards, trial offers, or free Pemfexy samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Pemfexy cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Pemfexy
  • Your insurance company will not pay for your Pemfexy prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Pemfexy cost without insurance?

Without insurance, Pemfexy costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Pemfexy intravenous solution (25 mg/mL) will cost around $4,000 for 20 milliliters.

How much does Pemfexy cost with insurance?

The copay for Pemfexy will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Pemfexy?

Pemfexy (pemetrexed injection) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Eagle Pharmaceuticals, Inc. Pemfexy is a type of antifolate used:

  • Alongside cisplatin for the initial treatment of patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC)
  • As a single agent for the maintenance treatment of patients with locally advanced or metastatic non-squamous NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy
  • As a single agent for the treatment of patients with metastatic non-squamous NSCLC that has returned after prior chemotherapy

Pemfexy is not recommended for the treatment of patients with squamous cell non-small cell lung cancer with cisplatin for the initial treatment of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not suitable for curative surgery.

What doses of Pemfexy are available?

Pemfexy is available in injection form, in the following doses: 25 mg/mL in a single-dose vial.

The recommended dose of Pemfexy as a single agent or with cisplatin, in patients with creatinine clearance of 45 mL/minute or greater, is 500 mg/m2, over ten minutes as an intravenous infusion on Day 1 of each 21-day cycle. Administer until disease progression or unacceptable toxicity.

Start folic acid 400 mcg to 1000 mcg orally once daily, 7 days before the first dose, and continue until 21 days after the last dose. Take vitamin B12, 1 mg intramuscularly 1-week before the first dose and every 3 cycles after. Also, take dexamethasone 4 mg orally twice daily, the day before, on the day, and the day after administration.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Pemfexy active ingredients

The active ingredient of Pemfexy is pemetrexed.

Pemfexy side effects

The most common side effects of Pemfexy in clinical trials include:

  • Tiredness, nausea, constipation, vomiting, and anorexia
  • Stomatitis/pharyngitis
  • Neutropenia
  • Anemia
  • Thrombocytopenia

In rare instances, Pemfexy can cause more serious side effects. These can include:

  • Myelosuppression
  • Renal Failure
  • Bullous and exfoliative skin toxicity
  • Interstitial pneumonitis
  • Radiation recall
  • Embryo-Fetal toxicity

Your doctor will assess the benefits of using Pemfexy against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Pemfexy to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Pemfexy drug interactions

Pemfexy can interact with other medications. These include:

  • Ibuprofen – modify the ibuprofen dosage for patients with a creatinine clearance between 45 mL/min and 79 mL/min

This list is not exhaustive and other prescription drugs may interact with Pemfexy.

Pemfexy contraindications

You should not use Pemfexy if you:

  • Are allergic to the active ingredient pemetrexed
  • Are allergic to any of the other ingredients in Pemfexy
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Pemfexy if you:

  • Are taking any of the medications that could interact with Pemfexy
  • Are breastfeeding or are planning to breastfeed

Pemfexy generic

Pemfexy is the trademark brand name for pemetrexed manufactured by Eagle Pharmaceuticals, Inc. A generic version of pemetrexed is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Pemfexy savings through NiceRx.

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.