Pentasa Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Has your physician prescribed you Pentasa medication? Do you need a simple solution to get your essential medication at a price you can afford? With our help, you may be able to enroll in the Pentasa assistance program and get your prescription for just $49 per month.*

NiceRx handles the full application process for you, helping you get easy access to the medications you need at an affordable price.

Your monthly Pentasa cost savings if eligible

Eligible individuals can get Pentasa prescriptions for a flat fee of just $49 per month, every month. Regardless of the retail price of the medication, you will only ever pay this flat monthly fee. You could save:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
250mg 120 capsules$370.35$49.00$321.35
250mg 480 capsules$1,455.72$49.00$1,406.72
500mg 120 capsules$732.13$49.00$683.13

Am I eligible for the Pentasa patient assistance program?

If you meet the eligibility criteria for Pentasa assistance, you could receive your Pentasa without paying the full retail price. At NiceRx, we review each patient assistance program application individually. 

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Pentasa patient assistance program? 

We do everything we can to make it as easy as possible to apply for the Pentasa patient assistance program. Our enrollment application is simple and straightforward. At this stage it’s important to provide important information for your application. We will need to know about any medications you’re taking, including Pentasa. The pharmaceutical manufacturers who make your medication also require that you detail both your healthcare provider, insurance, and your household income at this stage.  

If we determine that you may be eligible for Pentasa assistance, we’ll handle the full application process for you. We will help to enroll you in the Pentasa patient assistance program and will request your Pentasa medication refills on your behalf for up to a full year.

Is NiceRx a Pentasa coupons provider?

NiceRx is a service provider that helps eligible individuals access the Pentasa patient assistance program. Our service does not include free Pentasa samples, printable Pentasa manufacturer coupons, Pentasa savings cards, or Pentasa discounts. 

You may have read about various ways to obtain cheap Pentasa, however, it’s important to note that you will likely save more through NiceRx. Remember, you will only ever pay a flat monthly cost of $49 for your prescription. We are therefore not a Pentasa coupon, a Pentasa discount card, or a Pentasa copay card. 

Can NiceRx help me get Pentasa if I have insurance? 

We may be able to help in a variety of scenarios, for example if your insurance company won’t pay for your Pentasa medication, you have a high copay or coinsurance responsibility, or you don’t have insurance. 

How much is Pentasa with insurance?

The cost of Pentasa will vary depending on your healthcare plan. To find out what you may have to pay under the terms of your healthcare plan, your pharmacist or healthcare provider will be able to calculate your copay with your current insurance. 

How much does Pentasa cost without insurance?

Pentasa prices without insurance will vary between retailers. As a guide, you’ll pay around 

$450 for 60, 500 mg oral capsules.

What is Pentasa?

Pentasa is a medication prescribed to treat ulcerative colitis. Ulcerative colitis is an inflammatory bowel disease that causes inflammation and ulcers in bowels. Specifically, it causes the lining of your colon and rectum (your large intestine) to become inflamed. The lining can develop small breaks that may bleed (ulcers). The condition can give you abdominal pain, diarrhea, fever, cause weight loss, and anemia. Over time it can cause colon damage, inflammation of the liver (hepatitis), and even colon cancer.

Ulcerative colitis is a long-term condition that may be mild to severe. It can ease off for a time, but you may get flare-ups of stronger symptoms. What causes ulcerative colitis isn’t known for sure, but it’s thought to be a mix of genetics, immune system problems, changes in gut bacteria, and factors in your environment. 

Pentasa helps with ulcerative colitis as it reduces inflammation and pain in your bowel. It’s usually taken as a tablet that is swallowed, then it releases its active ingredient slowly when it’s in your digestive system. The medication can reduce the severity of symptoms and help prevent flare-ups.

Pentasa active ingredients

The active ingredient in Pentasa is mesalazine. Mesalazine works when it’s released into your bowel, rather than having an effect on your whole body. It has an anti-inflammatory medication.

Your immune system causes inflammation through a complex process that involves a number of steps and substances. Mesalazine disrupts part of this process. It stops a substance involved in inflammation from working, called prostaglandin. This reduces inflammation and any pain caused by ulcerative colitis, easing symptoms, and preventing flare-ups.

Pentasa side effects & Pentasa drug interactions

The most common side effects caused by Pentasa include:

  • Headaches
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Rashes
  • Flatulence

In rare instances, Pentasa can cause more serious side effects, including:

  • Severe allergic reactions
  • Liver and kidney disorders
  • Inflammation of the pancreas (pancreatitis)
  • Inflammation of parts of the heart (myocarditis and pericarditis) 

Before prescribing the medication, your physician will assess your risk of side effects versus the benefits of taking Pentasa. This isn’t a full list of all the side effects Pentasa can cause. You can read more about Pentasa side effects in the leaflet that comes with your medication. 

Medicines that may interact with Pentasa, potentially altering its effectiveness and making side effects more likely include:

  • Non-steroidal anti-inflammatory drugs (NSAIDs), like ibuprofen
  • Azathioprine, an immunosuppressive medication
  • Mercaptopurine (6-mercaptopurine), used for cancer and autoimmune diseases
  • Thioguanine, used to treat leukemia
  • Anticoagulants, like warfarin

Pentasa warnings & precautions

Don’t take Pentasa if you:

  • Are allergic to the active ingredient mesalazine
  • Are allergic to any of the other ingredients in Pentasa 
  • Are allergic to any other salicylates, like aspirin
  • Have severe liver or kidney problems

Talk to your physician before taking Pentasa if you:

  • Are taking any of the medications listed in the section above that can interact with Pentasa
  • Have, or have had, any kidney or liver problems
  • Are allergic to sulfasalazine
  • Have a medical condition that can make you prone to bleeding
  • Have a stomach ulcer or duodenal ulcer
  • Have lung problems, particularly asthma 
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed
  • Are over 65 years of age

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.