Prevymis Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Prevymis cost savings if eligible

With our assistance, you could access the Prevymis patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Prevymis patient assistance?

We review each Prevymis enrollment application individually to determine if you are eligible. Each assistance program has its eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Prevymis patient assistance program?

Our process makes it as easy as possible to apply for the Prevymis patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Prevymis, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Prevymis coupons provider?

NiceRx is not a Prevymis coupon, Prevymis discount card, or Prevymis copay card provider. We do not offer Prevymis manufacturer coupons, Prevymis discounts, rebates, Prevymis savings cards, trial offers, or free Prevymis samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Prevymis
  • Your insurance company will not pay for your Prevymis prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Prevymis cost without insurance?

Without insurance, Prevymis costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Prevymis oral tablets 240 mg will cost around $3,475 for 14 tablets.

How much does Prevymis cost with insurance?

The copay for Prevymis will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Prevymis?

Prevymis is an FDA (U.S. Food and Drug Administration) approved medication distributed by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.

Prevymis is an antiviral CMV DNA terminase complex inhibitor indicated for prophylaxis of cytomegalovirus (CMV infection) and disease in adult CMV-seropositive recipients [R+] of an allogeneic hematopoietic stem cell transplant (HSCT).

What doses of Prevymis are available?

Prevymis is available in tablet and injection form, in the following doses: 240 mg, 480 mg, 240 mg/12 mL (20 mg/mL) or 480 mg/24 mL (20 mg/mL) in a single-dose vial.

The recommended dose is 480 mg once daily orally or as an intravenous infusion over 1 hour through 100 days post-transplant. Dosage adjustment is required if co-administered with cyclosporine, to 240 mg once daily.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Prevymis active ingredients

The active ingredient of Prevymis is letermovir.

Prevymis side effects

The most common side effects of Prevymis in clinical trials compared to placebo include:

  • Nausea, vomiting
  • Peripheral edema
  • Cough
  • Headache, fatigue
  • Abdominal pain, diarrhea

In rare instances, Prevymis can cause more serious side effects. These can include:

  • Risk of Adverse Reactions or Reduced Therapeutic Effect Due to Drug Interactions

Your doctor will assess the benefits of using Prevymis against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Prevymis to the FDA. Visit, or call 1-800-FDA-1088.

Prevymis drug interactions

Co-administration of Prevymis may alter the plasma concentrations of other drugs and other drugs may alter the plasma concentrations. These include:

  • Cyclosporine
  • Inducers of P-GP and/or UGT – nafcillin, carbamazepine, phenobarbital, phenytoin, rifabutin, rifampin, thioridazine, bosentan, St. John’s wort, efavirenz, etravirine, nevirapine, pitavastatin, simvastatin, modafinil
  • OATP1B1/3 inhibitors
  • CYP3A substrates – midazolam, alfentanil, fentanyl, quinidine
  • OATP1B1/3 substrates – amiodarone, voriconazole, sirolimus, tacrolimus, omeprazole, pantoprazole
  • Warfarin
  • Glyburide, repaglinide, rosiglitazone
  • Atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin
  • Pimozide
  • Ergot alkaloids – ergotamine, dihydroergotamine

This list is not exhaustive and other prescription drugs may interact with Prevymis.

Prevymis contraindications

You should not use Prevymis if you:

  • Are allergic to the active ingredient letermovir
  • Are allergic to any of the other ingredients in Prevymis
  • Have severe (Child-Pugh C) hepatic impairment

Talk to your doctor before using Prevymis if you:

  • Are taking any of the medications that could interact with Prevymis
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Prevymis generic

Prevymis is the trademark brand name for letermovir distributed by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. A generic version of letermovir is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Prevymis savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.