Samsca Coupon & Prices

Is your Samsca medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Samsca medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

The Samsca patient assistance program is available to eligible individuals who are unable to afford their Samsca medication. At NiceRx, we can help you to enroll in the program for $49 per month.* We work directly with your healthcare provider to submit your enrollment application on your behalf. By handling the full enrollment process for you, we can help you get easy and affordable access to the medications you need. If you are successfully enrolled in the program, we will also request prescription refills on your behalf for up to 1 year.

Your monthly Samsca cost savings if eligible

The Samsca patient assistance program can provide your medication for free. We simply charge $49 a month per medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Samsca, regardless of the retail price.

Am I eligible for the Samsca patient assistance program?

To find out if you are eligible for Samsca assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Samsca patient assistance program?

Our application process aims to make it as easy as possible to apply for the Samsca patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Samsca.

NiceRx will review your application and determine whether you may be eligible for Samsca assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Samsca patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Samsca.

Is NiceRx a Samsca coupons provider?

NiceRx is a service provider that helps eligible individuals access the Samsca patient assistance program. We do not offer trial offers or free Samsca samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Samsca coupons, discount cards, or Samsca copay cards.

Can NiceRx help me get Samsca if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Samsca medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much is Samsca with insurance?

The cost of Samsca will vary by the terms of your healthcare plan. To find out what you might need to pay for Samsca with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

How much does Samsca cost without insurance?

Samsca prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Samsca oral tablets 15 mg typically cost $5,450 for 10 tablets.

What is Samsca?

Samsca contains the prescription medicine tolvaptan, which increases low sodium levels in the blood (hyponatremia) in adults with heart failure and specific hormone imbalances. Samsca does this by helping to remove water from your body as urine. This causes your body’s salt concentration to increase.

Samsca should not be used if you are dehydrated, if you can not tell you are thirsty, or if you are unable to urinate. Samsca can be dangerous if your low sodium levels are reversed too quickly. You must inform your doctor immediately if you have difficulty with your speech, swallowing, moving your arms or legs, any confusion, or seizures. You will need regular checks while you are taking this medicine.

Samsca active ingredients

Tolvaptan blocks certain receptors in your body known as vasopressin V2-receptors. When taken tolvaptan blocks the effects of vasopressin in the body. This causes you to get rid of more water in your urine and has the effect of raising your serum sodium concentrations. Tolvaptan does not increase the amount of sodium lost in your urine.

You should take Samsca with plenty of water once per day. When you start or if you restart this medicine, you will need to be observed in a hospital just in case you have any serious side effects. Samsca should only be used for up to 30 days as long-term use can cause liver damage.

Samsca side effects

The most common side effects caused by Samsca include:

  • Dry mouth
  • Increased thirst or urination
  • Hunger
  • Constipation
  • Feeling tired or weak

In rare instances, Samsca can cause more serious side effects. These can include:

  • Weakness, confusion, light-headed
  • Irregular heartbeats
  • Seizures
  • Weight loss
  • Increased thirst, difficulty urinating, heavy sweating, hot and dry skin
  • Upper right side stomach pain, vomiting, loss of appetite, fever, itching, yellow color to your skin or eyes
  • Problems with speech or muscle control, difficulty moving your arms and legs
  • Difficulty swallowing
  • Confusion
  • Mood changes

Your doctor will assess the benefits of using Samsca against your risk of side effects.

Samsca drug interactions

Samsca can interact with other medications. These include:

  • Antiviral treatments – amprenavir, atazanavir, boceprevir
  • Anticonvulsants to prevent seizures – carbamazepine, phenobarbital, phenytoin
  • Antibiotics for bacterial infections – clarithromycin, rifampin, telithromycin
  • Antifungal treatments – itraconazole, ketoconazole, voriconazole
  • DMARDs (disease-modifying antirheumatic drugs) for rheumatoid arthritis – teriflunomide
  • Treatments for heart arrhythmias (irregular heartbeat) – amiodarone, dronedarone
  • Blood thinners – apixaban, edoxaban, heparin

This list is not exhaustive and other drugs may interact with Samsca.

Samsca warning and precautions

You should not use Samsca if you:

  • Are allergic to the active ingredient tolvaptan
  • Are allergic to any of the other ingredients in Samsca
  • Are unable to urinate
  • Are unable to tell that you are thirsty
  • Are severely dehydrated and feel like you might pass out
  • Need your sodium levels to be raised quickly
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Samsca if you:

  • Are taking any of the medications that could interact with Samsca
  • Have kidney disease or urination problems
  • Have liver problems
  • Drink large amounts of alcohol
  • Are malnourished
  • Use desmopressin or a water pill
  • Are pregnant or are planning to become pregnant

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.

DISCLAIMER: NiceRx is a conduit between consumers in need of prescription drug savings. NiceRx is not affiliated or contracted with any of the pharmaceutical companies or products which are illustrated on this website. NiceRx is not compensated in any capacity by any of the manufacturers. All of the information about prescription drugs on this website has not been provided to NiceRx by the manufacturer.