Tosymra Coupon & Prices

Is your Tosymra medication too expensive?

Get notified when Tosymra medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Tosymra coupon provider?

At NiceRx, we help eligible individuals access the Tosymra patient assistance program. This means that we are not a Tosymra coupon, a Tosymra discount card, or a Tosymra copay card provider. We do not offer any medication trial offers, or free Tosymra samples.

Tosymra patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Tosymra cheaper if I have insurance?

How much does Tosymra cost without insurance?

Tosymra costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Tosymra nasal spray (10 mg/inh) will typically cost around $625 for 6 sprays.

How much does Tosymra cost with insurance?

The copay of Tosymra will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Tosymra?

Tosymra nasal spray is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Upsher-Smith Laboratories, LLC. It is a serotonin receptor agonist used for the acute treatment of migraine headaches and migraine attacks with or without an aura in adults.

Tosymra is not recommended as a preventive treatment for migraines or for the treatment of cluster headaches.

What doses of Tosymra are available?

Tosymra is available as a nasal spray, in the following doses: 10 mg in a single dose.

Use the spray at the first sign of a migraine. The recommended dose is usually 1 spray into one nostril. The maximum dose in a 24-hour period is 30 mg. Doses must be taken at least one hour apart.

See the full prescribing information for the instructions for use and further patient information. Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Tosymra active ingredients

Tosymra contains sumatriptan as the active ingredient.

Tosymra side effects

The most common side effects of Tosymra in clinical trials include:

  • Tingling
  • Dizziness/vertigo
  • Drowsiness
  • Feeling of heaviness
  • Pressure sensation
  • Application site reactions
  • Throat irritation

In rare instances, Tosymra can cause more serious side effects. These can include:

  • Myocardial infarction (heart attack) and Prinzmetal’s angina – evaluate patients with multiple cardiovascular risk factors
  • Arrhythmias
  • Cerebral hemorrhage, subarachnoid hemorrhage, and stroke
  • Gastrointestinal ischemia and reactions, peripheral vasospastic reactions
  • Medication overuse headache
  • Serotonin syndrome
  • Hypertensive crisis
  • Hypersensitivity reactions – angioedema and anaphylaxis
  • Seizures
  • Local irritation – burning and abnormal taste

Your doctor will assess the benefits of using Tosymra against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions to Tosymra to the FDA. Visit, or call 1-800-FDA-1088.

Tosymra drug interactions

Tosymra can interact with other medications. These include:

  • Monoamine oxidase inhibitors (MAOIs) – isocarboxazid, linezolid, metaxalone, methylene blue
  • Other drugs that increase serotonin – St. John’s wort, certain antidepressants (including SSRIs such as fluoxetine and paroxetine, SNRIs such as duloxetine and venlafaxine)
  • Ergotamine medication – dihydroergotamine
  • Triptan drugs – zolmitriptan, rizatriptan

This list is not exhaustive and other prescription drugs may interact with Tosymra. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Tosymra contraindications

You should not use Tosymra if you:

  • Are allergic to the active ingredient sumatriptan
  • Are allergic to any of the other ingredients in Tosymra
  • Have a history of coronary artery disease or coronary vasospasm
  • Have Wolff-Parkinson-White syndrome or other cardiac accessory conduction pathway disorders
  • Have ischemic bowel disease
  • Have uncontrolled hypertension (high blood pressure)
  • Have heart problems or a history of heart problems
  • Have narrowing of blood vessels in your legs, arms, stomach, or kidney (peripheral vascular disease)
  • Have severe liver problems
  • Suffer from hemiplegic migraines or basilar migraines
  • Have had a stroke, transient ischemic attacks, or problems with your blood circulation
  • Have taken eletriptan, frovatriptan, naratriptan, rizatriptan, ergotamines, or dihydroergotaminein in the last 24 hours

Talk to your doctor before using Tosymra if you:

  • Are taking any of the medications that could interact with Tosymra
  • Have high cholesterol
  • Have diabetes
  • Smoke
  • Are overweight
  • Have heart disease or a family history of heart disease or stroke
  • Have kidney problems
  • Have liver problems
  • Suffer from seizures
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Tosymra generic

Tosymra is the trademark brand name for sumatriptan manufactured by Upsher-Smith Laboratories, LLC. A generic version of sumatriptan is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Tosymra savings through NiceRx.

Related medications

Related conditions

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.