Uptravi Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

If you are unable to afford your Uptravi medication, we may be able to help. The NiceRx program helps uninsured and underinsured individuals with chronic conditions who cannot afford their medications. If you qualify for prescription assistance, you can receive your Uptravi prescription for $49 per month!* 

Have you been prescribed Uptravi medication for PAH? Are you worried about the cost of your prescription? By working directly with healthcare providers, we help eligible individuals access the medicines they need through patient assistance programs for prescription medications. With our help, you may be able to get your Uptravi for $49 per month*, through the Uptravi patient assistance program. 

We will handle the full application process on your behalf. NiceRx will help you to get easy and affordable access to the medications you need, without the hassle and stress. 

Your monthly Uptravi cost savings if eligible

If eligible for the Uptravi patient assistance program, you will only pay a flat monthly fee of $49 per month. Every month, you could save:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
400mcg 540 tablets$99,999.00$49.00$99,950.00
600mcg 30 tablets$8,990.00$49.00$8,941.00
800mcg 30 tablets$8,990.00$49.00$8,941.00
1000mcg 30 tablets$8,990.00$49.00$8,941.00
1200mcg 30 tablets$8,990.00$49.00$8,941.00
1400mcg 30 tablets$8,990.00$49.00$8,941.00
1600mcg 30 tablets$8,990.00$49.00$8,941.00
200mcg 300 tablets$5,800.00$49.00$5,751.00

Am I eligible for the Uptravi patient assistance program?

If you meet the eligibility criteria for the Uptravi patient assistance program, you could receive your Uptravi without paying the full retail price. Please note, that the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Uptravi patient assistance program? 

At NiceRx, we will guide you through the process of applying for Uptravi assistance. Our process is simple, straightforward, and stress-free, and we make it as easy as possible to apply for the Uptravi patient assistance program. Simply fill in our enrollment application.  

Start by telling us about any medications you’re taking, including Uptravi. We’ll also ask for details about your healthcare provider, your insurance plan, and your household income. 

We will review your enrollment application and once we determine that you may be eligible for Uptravi assistance, we’ll handle the full application process for you. If you are successfully enrolled in the Uptravi patient assistance program, we’ll also request your refills on your behalf for up to 12 months.

Is NiceRx a Uptravi coupons provider?

We are not a Uptravi coupon, a Uptravi discount card, or a Uptravi copay card provider. NiceRx is a service provider that helps eligible individuals access the Uptravi patient assistance program. We don’t offer printable Uptravi manufacturer coupons, Uptravi discounts, rebates, Uptravi savings cards, trial offers, or free Uptravi samples.

Can NiceRx help me get Uptravi if I have insurance? 

If you don’t have insurance, we may be able to help. We may also be able to assist if your insurance company won’t pay for your Uptravi medication, or you have a high copay or coinsurance responsibility. Complete your enrollment application online to find out your potential eligibility. 

How much is Uptravi with insurance?

The cost of Uptravi depends on your specific healthcare plan. Your insurance provider or pharmacist will be able to calculate your copay with your current insurance, to find out exactly how much you will need to pay for Uptravi with insurance. 

How much does Uptravi cost without insurance?

Uptravi prices without insurance will vary depending on the amount and the dose you buy, and where you buy the medication from. As a guide, a pack of 60, 200 mcg Uptravi tablets will cost around $11,000.

What is Uptravi?

Uptravi is a medication prescribed to adults to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the vessels inside your lungs. Those that suffer from it will experience constricting and narrowing (sometimes blocking and damage) of the vessels inside their lungs. When this occurs, blood pressure in the lungs increases, reducing oxygen levels. 

PAH can make you feel short of breath and can cause chest pain, fatigue, heart palpitations, and fainting. It can make it harder for you to exercise or perform other physical activities. Unfortunately, there is no cure for PAH. While it often gets progressively worse, Uptravi can help you to manage it and lessen the symptoms.  

The medication is taken as an oral tablet and helps to relax the muscle tissue in the blood vessels inside your lungs. This can help to open the arteries up, reducing blood pressure, and improving how much oxygen you can take into your blood. This can reduce your symptoms of PAH and slow the development of the disease.

Uptravi active ingredients

The active ingredient in Uptravi is called selexipag. It helps to relax and widen the blood vessels in your lungs, reducing blood pressure and increasing oxygen absorption. When you take Uptravi, the active ingredient selexipag is absorbed in your bloodstream. It travels to the blood vessels in your lung where it attaches to areas on the surface of the muscle tissue called prostacyclin receptors. This activates the receptors and they trigger a process that relaxes the muscle tissue.

Uptravi side effects & Uptravi drug interactions

The most common side effects experienced by people that take Uptravi include:

  • Headaches
  • Diarrhea
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Decreased appetite
  • Muscle pain
  • Joint pain
  • Jaw pain
  • Pain in your arms and legs
  • Rashes
  • Flushing
  • A low red blood cell count (anemia)

In rare instances, Uptravi can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • An increased heart rate

Uptravi can interact with other medications, including: 

  • Any other medications taken to treat pulmonary arterial hypertension 
  • Strong CYP2C8 inhibitors medications taken to lower your blood fat levels (cholesterol and lipids), like statins, fibrates, or niacin

Speak to your physician if you are taking these medications as they could impact the effectiveness of Uptravi and increase the severity of some side effects. 

Uptravi warnings & precautions

Don’t take Uptravi if you:

  • Are allergic to the active ingredient selexipag
  • Are allergic to any of the other ingredients in Uptravi (you can find these listed in the leaflet which comes with the medication)
  • Have any heart problems, like heart defects, poor blood flow to your heart, or have had a heart attack
  • Are taking gemfibrozil, a medication used to lower the level of fat in the blood
  • Are under 18 years of age

Talk to your doctor before taking Uptravi if you:

  • Are taking any of the medications that could interact with Uptravi 
  • Have any liver problems
  • Have any kidney problems
  • Have any thyroid problems
  • Have a condition called pulmonary veno-occlusive disease that causes your pulmonary veins to narrow
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Uptravi can cause side effects that can affect your ability to drive, operate machinery, or perform other dangerous activities. 

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.