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Uptravi Patient assistance program

Is your Uptravi medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Uptravi medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
  • Next steps after qualifying
  • Uploading documents and billing
  • SSN & billing information
  • Medication delivery time

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Uptravi cost savings if eligible

If eligible for the Uptravi patient assistance program, you will only pay a flat monthly fee of $49 per month. Every month, you could save:

Strength Avg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
400mcg 540 tablets$99,999.00$49.00$99,950.00
600mcg 30 tablets$8,990.00$49.00$8,941.00
800mcg 30 tablets$8,990.00$49.00$8,941.00
1000mcg 30 tablets$8,990.00$49.00$8,941.00
1200mcg 30 tablets$8,990.00$49.00$8,941.00
1400mcg 30 tablets$8,990.00$49.00$8,941.00
1600mcg 30 tablets$8,990.00$49.00$8,941.00
200mcg 300 tablets$5,800.00$49.00$5,751.00

Am I eligible for the Uptravi patient assistance program?

If you meet the eligibility criteria for the Uptravi patient assistance program, you could receive your Uptravi without paying the full retail price. Please note, that the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Uptravi patient assistance program? 

At NiceRx, we will guide you through the process of applying for Uptravi assistance. Our process is simple, straightforward, and stress-free, and we make it as easy as possible to apply for the Uptravi patient assistance program. Simply fill in our enrollment application.  

Start by telling us about any medications you’re taking, including Uptravi. We’ll also ask for details about your healthcare provider, your insurance plan, and your household income. 

We will review your enrollment application and once we determine that you may be eligible for Uptravi assistance, we’ll handle the full application process for you. If you are successfully enrolled in the Uptravi patient assistance program, we’ll also request your refills on your behalf for up to 12 months.

Is NiceRx a Uptravi coupons provider?

We are not a Uptravi coupon, a Uptravi discount card, or a Uptravi copay card provider. NiceRx is a service provider that helps eligible individuals access the Uptravi patient assistance program. We don’t offer printable Uptravi manufacturer coupons, Uptravi discounts, rebates, Uptravi savings cards, trial offers, or free Uptravi samples.

Can NiceRx help me get Uptravi if I have insurance? 

If you don’t have insurance, we may be able to help. We may also be able to assist if your insurance company won’t pay for your Uptravi medication, or you have a high copay or coinsurance responsibility. Complete your enrollment application online to find out your potential eligibility. 

How much is Uptravi with insurance?

The cost of Uptravi depends on your specific healthcare plan. Your insurance provider or pharmacist will be able to calculate your copay with your current insurance, to find out exactly how much you will need to pay for Uptravi with insurance. 

How much does Uptravi cost without insurance?

Uptravi prices without insurance will vary depending on the amount and the dose you buy, and where you buy the medication from. As a guide, a pack of 60, 200 mcg Uptravi tablets will cost around $11,000.

What is Uptravi?

Uptravi is a medication prescribed to adults to treat pulmonary arterial hypertension (PAH), which is high blood pressure in the vessels inside your lungs. Those that suffer from it will experience constricting and narrowing (sometimes blocking and damage) of the vessels inside their lungs. When this occurs, blood pressure in the lungs increases, reducing oxygen levels. 

PAH can make you feel short of breath and can cause chest pain, fatigue, heart palpitations, and fainting. It can make it harder for you to exercise or perform other physical activities. Unfortunately, there is no cure for PAH. While it often gets progressively worse, Uptravi can help you to manage it and lessen the symptoms.  

The medication is taken as an oral tablet and helps to relax the muscle tissue in the blood vessels inside your lungs. This can help to open the arteries up, reducing blood pressure, and improving how much oxygen you can take into your blood. This can reduce your symptoms of PAH and slow the development of the disease.

Uptravi active ingredients

The active ingredient in Uptravi is called selexipag. It helps to relax and widen the blood vessels in your lungs, reducing blood pressure and increasing oxygen absorption. When you take Uptravi, the active ingredient selexipag is absorbed in your bloodstream. It travels to the blood vessels in your lung where it attaches to areas on the surface of the muscle tissue called prostacyclin receptors. This activates the receptors and they trigger a process that relaxes the muscle tissue.

Uptravi side effects & Uptravi drug interactions

The most common side effects experienced by people that take Uptravi include:

  • Headaches
  • Diarrhea
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Decreased appetite
  • Muscle pain
  • Joint pain
  • Jaw pain
  • Pain in your arms and legs
  • Rashes
  • Flushing
  • A low red blood cell count (anemia)

In rare instances, Uptravi can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • An increased heart rate

Uptravi can interact with other medications, including: 

  • Any other medications taken to treat pulmonary arterial hypertension 
  • Strong CYP2C8 inhibitors medications taken to lower your blood fat levels (cholesterol and lipids), like statins, fibrates, or niacin

Speak to your physician if you are taking these medications as they could impact the effectiveness of Uptravi and increase the severity of some side effects. 

Uptravi warnings & precautions

Don’t take Uptravi if you:

  • Are allergic to the active ingredient selexipag
  • Are allergic to any of the other ingredients in Uptravi (you can find these listed in the leaflet which comes with the medication)
  • Have any heart problems, like heart defects, poor blood flow to your heart, or have had a heart attack
  • Are taking gemfibrozil, a medication used to lower the level of fat in the blood
  • Are under 18 years of age

Talk to your doctor before taking Uptravi if you:

  • Are taking any of the medications that could interact with Uptravi 
  • Have any liver problems
  • Have any kidney problems
  • Have any thyroid problems
  • Have a condition called pulmonary veno-occlusive disease that causes your pulmonary veins to narrow
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Uptravi can cause side effects that can affect your ability to drive, operate machinery, or perform other dangerous activities. 

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.