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Xcopri Patient assistance program

Is your Xcopri medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Xcopri medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Xcopri cost savings if eligible

If you are eligible for the Xcopri patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Xcopri prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Xcopri patient assistance program?

We will review your application to determine whether you are eligible for the Xcopri patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Xcopri patient assistance program?

We make it as easy as possible to apply for the Xcopri patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Xcopri. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Xcopri assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Xcopri patient assistance program, and we will automatically request your Xcopri medication refills for up to 1 year.

Is NiceRx an Xcopri coupons provider?

We are a service provider that helps eligible individuals access the Xcopri patient assistance program. That means that we do not offer printable Xcopri manufacturer coupons, Xcopri discounts, or free Xcopri samples. We are not an Xcopri coupon provider or Xcopri discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Xcopri if I have insurance?

We may be able to help you to access Xcopri patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Xcopri medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Xcopri cost without insurance?

Xcopri cost without insurance will vary depending on where you buy it. As a guide, Xcopri oral tablets (250 mg daily dose) usually costs $1,100 for 56 tablets. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Xcopri cost with insurance?

The copay for Xcopri with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Xcopri?

Xcopri is an FDA (Food and Drug Administration) approved medication manufactured by SK Life Science, Inc. Xcopri is indicated for the treatment of partial-onset seizures in adult patients.

Xcopri is a federally controlled substance because it can be abused or lead to dependence. Xcopri should be kept in a safe place to prevent misuse and abuse. Tell your healthcare provider if you have ever abused or been dependent on alcohol, prescription drugs, or street drugs. Selling or giving away Xcopri may harm others and is against the law.

What doses of Xcopri are available?

Xcopri is available in tablet form, in the following doses: 12.5 mg, 25 mg, 50 mg, 100 mg, 150 mg, and 200 mg.

Xcopri (cenobamate tablets) are swallowed whole. Do not crush or chew. The recommended initial dosage is 12.5 mg tablets once daily, titrated to the recommended maintenance dosage of 200 mg once daily.

The recommended titration schedule should not be exceeded. The maximum daily dosage is 400 mg once daily.

For patients with mild or moderate hepatic impairment, the maximum recommended dosage is 200 mg once daily.

Xcopri should be stored at room temperature away from light and moisture.

Always speak with your healthcare provider about any changes to your dose or for any medical advice so they can evaluate your condition.

Xcopri active ingredients

The exact mechanism of action by which cenobamate works in patients with partial-onset seizures is not known. Cenobamate has been shown to reduce repetitive neuronal firing by inhibiting voltage-gated sodium currents. It is also a positive allosteric modulator of the γ-aminobutyric acid (GABAA) ion channel.

Xcopri side effects

The most common side effects caused by Xcopri in clinical studies include:

  • Feeling sleepy and tired
  • Dizziness
  • Double vision
  • Headache
  • Nausea, vomiting
  • Constipation, decreased appetite, diarrhea, or weakness

In rare instances, Xcopri can cause more serious side effects. These can include:

  • Problems with the electrical system of the heart (QT shortening) increased heartbeats that last a long time or fainting
  • Problems with your nervous system – dizziness, problems walking or with coordination, feeling sleepy or tired, difficulty concentrating, remembering, and thinking clearly, problems with vision
  • Serious or life-threatening allergic reactions may affect organs and other parts of your body like the liver or blood cells. You may or may not have a rash with these types of reactions. Call your healthcare provider immediately if you have – swelling of your face, eyes, lips, or tongue, trouble swallowing or breathing, skin rash, hives, fever, swollen glands, or sore throat, painful sores in the mouth or around your eyes, yellowing of your skin or eyes, unusual bruising or bleeding, severe fatigue, weakness, or muscle pain, frequent infections that do not go away
  • Like other antiepileptic drugs (AED) Xcopri may cause suicidal thoughts, panic attacks, unusual changes in mood or behavior, irritability, aggression
  • Stopping Xcopri suddenly can cause seizures that will not stop (status epilepticus)
  • Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity – fever, rash, lymphadenopathy, and/or facial swelling, in association with other organ system involvement, such as hepatitis, nephritis, hematological abnormalities, myocarditis, or myositis sometimes resembling an acute viral infection. Eosinophilia is often present

Your doctor will assess the benefits of using Xcopri against your risk of side effects.

Patients are encouraged to report negative side effects or adverse events of Xcopri to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Xcopri drug interactions

Xcopri can interact with other medications. These include:

  • Phenytoin – decrease phenytoin dosage gradually by up to 50%
  • Phenobarbital and Clobazam – reduce the dosage as required when used with Xcopri
  • Lamotrigine, carbamazepine – increase the dosage as required when used with Xcopri
  • CYP2B6 and CYP3A substrates – increase the dosage as required when used with Xcopri
  • CYP2C19 substrates – reduce the dosage as required when used with Xcopri
  • Oral contraceptives – effectiveness of oral contraceptives may be reduced when given with Xcopri. Women are advised to use additional or alternative non-hormonal birth control
  • Xcopri can shorten the QT interval, therefore, it should be given with caution when given with other drugs that shorten the QT interval

This list is not exhaustive and other prescription drugs may interact with Xcopri. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Xcopri contraindications

You should not use Xcopri if you:

  • Are allergic to the active ingredient cenobamate
  • Are allergic to any of the other ingredients in Xcopri

Talk to your doctor before using Xcopri if you:

  • Are taking any of the medications that could interact with Xcopri
  • Have a genetic problem called familial short QT syndrome that affects the electrical system of the heart
  • Are taking antiepileptic drugs (AED) -the relative risk for suicidal thoughts or behavior was higher in clinical trials in patients with epilepsy than in clinical trials in patients with psychiatric or other conditions. Patients treated with any AED should be monitored for the worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior
  • Are taking other CNS depressants, including alcohol – these may increase the risk of neurological adverse reactions, including sedation and somnolence
  • Are breastfeeding or are planning to breastfeed
  • Have liver, kidney, or blood problems
  • Have had an allergic reaction to a medicine that caused a rash or affected internal organs, like the liver or blood cells
  • Are pregnant or are planning to become pregnant – you may need to register on North American Antiepileptic Drug (NAAED) Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334 or going to www.aedpregnancyregistry.org

Xcopri generic

Xcopri is the trademark brand name for cenobamate manufactured by SK Life Science, Inc. A generic version of cenobamate is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Xcopri savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.