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Xywav Patient assistance program

Is your Xywav medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Xywav medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

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  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Xywav cost savings if eligible

If you are eligible for the Xywav patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Xywav prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Xywav patient assistance program?

We will review your application to determine whether you are eligible for the Xywav patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Xywav patient assistance program?

We make it as easy as possible to apply for the Xywav patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Xywav. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Xywav assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Xywav patient assistance program, and we will automatically request your Xywav medication refills for up to 1 year.

Is NiceRx a Xywav coupons provider?

We are a service provider that helps eligible individuals access the Xywav patient assistance program. That means that we do not offer printable Xywav manufacturer coupons, Xywav discounts, or free Xywav samples. We are not a Xywav coupon provider or Xywav discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Xywav if I have insurance?

We may be able to help you to access Xywav patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Xywav medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Xywav cost without insurance?

Xywav cost without insurance will vary depending on where you buy it. As a guide, Xywav oral liquid (0.5 g/mL) usually costs $5,800 for 180 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Xywav cost with insurance?

The copay for Xywav with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Xywav?

Xywav is a prescription medication containing calcium, magnesium, potassium, and sodium oxybates. Xywav is manufactured by Jazz Pharmaceuticals and has FDA approval (U.S. Food and Drug Administration) as a central nervous system depressant for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age and older with narcolepsy, and for idiopathic hypersomnia (a type of sleep disorder) in adults patients.

Xywav is a controlled substance that can only be prescribed through a Risk Evaluation Mitigation Strategy (REMS) program. This means only certain doctors and pharmacies are able to prescribe and dispense this medication.

What doses of Xywav are available?

Xywav is available in oral solution form, in the following doses: 0.5 g/mL total salts (equivalent to 0.413 g/mL of oxybate).

If you currently take Xyrem for narcolepsy, your starting dosage of Xywav will likely match your current dosage of Xyrem. Please see the full prescribing information and medication guide for the complete boxed warning. Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Xywav active ingredients

The active ingredient of Xywav is a form of gamma-hydroxybutyrate (GHB).

Xywav side effects

The most common side effects of Xywav in clinical trials compared to placebo include:

  • Headache, nausea, dizziness
  • Decreased appetite, diarrhea
  • Parasomnia (sleepwalking), drowsiness
  • Hyperhidrosis, anxiety, vomiting
  • In pediatric studies, common adverse reactions include bedwetting, nausea, headache, vomiting, dry mouth, weight decreased, decreased appetite, and dizziness

In rare instances, Xywav can cause more serious side effects. These can include:

  • CNS depression
  • Depression and suicidality
  • Confusion, anxiety

Your doctor will assess the benefits of using Xywav against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Xywav to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Xywav drug interactions

Xywav can interact with other medications. These include:

  • Divalproex sodium – an initial reduction in Xywav dose is recommended
  • Central nervous system (CNS) depressants such as opioid analgesics, benzodiazepines, sedating antidepressants, antipsychotics, sedating anti-epileptic medicines, general anesthetics, muscle relaxants, alcohol, or street drugs

This list is not exhaustive and other prescription drugs may interact with Xywav.

Xywav contraindications

You should not use Xywav if you:

  • Are allergic to the active ingredient, calcium oxybate, magnesium oxybate, potassium oxybate, and sodium oxybates
  • Are allergic to any of the other ingredients in Xywav
  • Are pregnant or are planning to become pregnant
  • Are taking sedative-hypnotics or alcohol
  • Have succinic semialdehyde dehydrogenase deficiency

Talk to your doctor before using Xywav  if you:

  • Are taking any of the medications that could interact with Xywav
  • Are breastfeeding or are planning to breastfeed
  • Have liver disease
  • Have breathing problems (such as sleep apnea, or asthma)
  • Have a personal or family history of regular use or abuse of drugs and alcohol
  • Have mental health problems such as depression
  • Have a family or personal history of suicidal thoughts or attempts

Xywav generic

Xywav is the trademark brand name for calcium, magnesium, potassium, and sodium oxybates manufactured by Jazz Pharmaceuticals. A generic version of calcium, magnesium, potassium, and sodium oxybates is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Xywav savings through NiceRx.

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.