compareMydayis vs Adderall

Mydayis vs Adderall

Drug facts and comparison

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Medically reviewed by  Jamie Winn, PharmD

Mydayis

Dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, and amphetamine aspartate monohydrate

Adderall

dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine aspartate monohydrate, amphetamine sulfate

Uses

Treatment of attention deficit hyperactivity disorder in adults and children 13 years of age and over

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To treat attention deficit hyperactivity disorder (ADHD) in adults and children 6 years of age or older

Summary

Brand name: Mydayis
Brand name: Adderall
Manufacturer: Shire US Inc.
Manufacturer: Shire US Inc.
Active ingredient: Dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, and amphetamine aspartate monohydrate
Active ingredient: dextroamphetamine sulfate, dextroamphetamine saccharate, amphetamine aspartate monohydrate, amphetamine sulfate
Indication: Treatment of attention deficit hyperactivity disorder in adults and children 13 years of age and over
Indication: To treat attention deficit hyperactivity disorder (ADHD) in adults and children 6 years of age or older

Side Effects

Most common:

  • Dry mouth
  • Nausea
  • Reduced appetite
  • Weight loss
  • Trouble sleeping
  • An increased heart rate
  • Irritability
  • Anxiety

More serious:

  • Heart problems, including increased blood pressure, a faster heart rate, strokes, heart attacks, and sudden death
  • New or worsening mental health problems, including aggressiveness, anxiety, bipolar disorder, depression, and psychosis
  • Severe allergic reactions to the medication
  • Seizures
  • Serotonin syndrome – a dangerous condition caused by rises in serotonin levels
  • Circulation problems in fingers and toes
  • A slowing and stunting of growth in children

Most common:

  • Headache, dizziness
  • Stomach pain
  • Weight loss, loss of appetite
  • Feeling anxious, fast heartrate, changes in mood
  • Trouble sleeping

More serious:

  • Chest pain, difficulty breathing, feeling faint
  • Hallucinations, paranoia, aggression
  • Feeling numb, pain, changes in skin color, unexplained wounds
  • Seizures
  • Changes in vision

Drug Interactions

Severe interactions
  • Antidepressants – citalopram, escitalopram, fluoxetine
  • Monoamine oxidase inhibitor (MAOI) – isocarboxazid, linezolid, methylene blue
Serious interactions
  • Proton pump inhibitors – esomeprazole, lansoprazole, omeprazole
  • Antiarrhythmics – dronedarone
  • NSAIDs – celecoxib
  • Immunosuppressants – ozanimod
  • Antipsychotics – haloperidol
Moderate interactions
  • Anticonvulsants – phenobarbital, phenytoin
Severe interactions
  • Antidepressants – citalopram, fluoxetine, sertraline, venlafaxine
Serious interactions
  • NSAIDs – celecoxib
  • Antipsychotics – haloperidol
  • Proton pump inhibitors – esomeprazole, omeprazole
  • Antiarrhythmics – amiodarone, dronedarone
Moderate interactions
  • Anticonvulsants – carbamazepine, phenobarbital, phenytoin

Warnings

You should not take Mydayis if you:

  • Are allergic to the active ingredients dextroamphetamine sulfate, amphetamine sulfate, dextroamphetaminesaccharate, or amphetamine aspartate monohydrate
  • Are allergic to any of the other ingredients in Mydayis
  • Have had an allergic reaction to any other medications containing amphetamines
  • Are taking a medication called a monoamine oxidase inhibitor (MAOI), or have taken one in the last 14 days
  • Are breastfeeding or are planning to breastfeed

You should talk to your doctor before using Mydayis if you:

  • Are taking any of the medications that could interact with Mydayis
  • Have any heart problems
  • Have hypertension (high blood pressure)
  • Have any kidney problems
  • Have any mental health problems, like psychosis, bipolar disorder, or depression
  • Have any circulation problems in your fingers or toes
  • Have ever had a seizure
  • Are pregnant or are planning to become pregnant

Are breastfeeding or are planning to breastfeed

You should not take Adderall if you:

  • Are allergic to the active ingredient amphetamine salts
  • Are allergic to any of the other ingredients in Adderall
  • Have used a MAO inhibitor in the past 14 days, such as isocarboxazid, rasagiline, selegiline, or tranylcypromine
  • Are younger than 3 years old
  • Are breastfeeding or are planning to breastfeed

You should talk to your doctor before using Adderall if you:

  • Have had problems with drug or alcohol abuse
  • Have a history of depression, mental illness, bipolar disorder, or suicidal thoughts or actions
  • Have glaucoma
  • Have an overactive thyroid
  • Have severe agitation
  • Have high blood pressure, heart disease or coronary artery disease
  • Have vascular disease
  • Have motor tics or Tourette’s syndrome
  • Suffer from seizures
  • Have liver or kidney disease
  • Blood circulation problems in your hands or feet
  • Are pregnant or are planning to become pregnant

Dosage

Once daily

Once daily

Cost

100 Mydayis capsules, extended-release 12.5 mg will cost around $1,150 for 100 capsules

100 Adderall tablets, 5 mg will cost around $950

FAQs

According to the National Institute on Mental Health, ADHD is one of the most common mental health disorders affecting children. Mydayis and Adderall are brand names for prescription drugs used for the treatment of attention deficit hyperactivity disorder (ADHD). They are both amphetamine products available as extended-release formulations making them long-acting drugs.

Mydayis and Adderall are both Schedule II controlled substances under the Controlled Substances Act. Schedule II substances have a high potential for substance abuse, which can lead to dependence both psychologically and physically.

Here we will explain how they work, their similarities and differences, their side effects, and more. This should provide you with the basics to better understand your options.

What is Mydayis?

Mydayis is an FDA-approved (U.S. Food and Drug Administration) medication manufactured by Shire US Inc. It is a prescription medication given to adults and children aged 13 years of age and over for the treatment of ADHD.

ADHD is a condition that causes differences in brain development and activity. Common ADHD symptoms include inattention, impulsive behavior, excess energy, and difficulties with controlling emotions. It usually emerges and is diagnosed in childhood, often between the ages of 6 and 12. It can be diagnosed later in life though. ADHD can be very disruptive to your life, affecting performance at school and in the workplace, as well as interfering with your home and social life.

Mydayis contains four active ingredients; dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, and amphetamine aspartate monohydrate. These are mixed amphetamine salts that stimulate activity in your brain.

Mydayis increases the levels of natural chemicals in your brain called neurotransmitters (norepinephrine and dopamine). These neurotransmitters stimulate brain activity, particularly in areas involved with motivation, reward, memory, and attention. This has been shown to improve attention and focus, reduce impulsivity, and alleviate other symptoms of ADHD.

Mydayis may also be used off-label to treat narcolepsy, a sleep problem that can cause extreme drowsiness during the day and sudden attacks of sleep.

Mydayis dosage

Mydayis is available in extended-release capsule form, in the following doses: 12.5 mg, 25 mg, 37.5 mg, and 50 mg.

Take Mydayis with or without food once a day in the morning. Its effects will last for around 16 hours. Mydayis capsules have a triple-bead release action and contain three types of beads per capsule: 33% of the beads are immediate-release, 33% of the beads are delayed-release working at pH 5.5, and 33% of the beads are delayed-release working at pH 7.0. Mydayis releases its medication in three phases.

What is Adderall?

Adderall is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire US Inc. Adderall is a central nervous system stimulant medication, used to treat ADHD in children (ages 6-12), adolescents (ages 13-17), and adults. It is also approved to treat narcolepsy. It is also thought to work by increasing the concentration of dopamine and norepinephrine in the brain.

The active ingredients in Adderall are amphetamine and dextroamphetamine. Adderall can become physically addictive and cause withdrawal symptoms when stopped.

Adderall dosage

Adderall is available as an immediate-release tablet formulation, in the following doses: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg. It is also available in the extended-release form (Adderall XR) of a capsule in the following doses: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg.

Your daily dose will be based on your age:

  • Children aged 6-17 years of age – 10 mg once daily in the morning
  • Adults – 20 mg once daily in the morning

For additional safety information, read the full prescribing information and medication guides. Always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Common side effects of Mydayis and Adderall

The most common side effects of Mydayis in clinical trials include:

  • Dry mouth
  • Nausea
  • Reduced appetite
  • Weight loss
  • Trouble sleeping
  • An increased heart rate
  • Irritability
  • Anxiety

More serious side effects of Mydayis include:

  • Heart problems, including increased blood pressure, a faster heart rate, strokes, heart attacks, and sudden death
  • New or worsening mental health problems, including aggressiveness, anxiety, bipolar disorder, depression, and psychosis
  • Severe allergic reactions to the medication
  • Seizures
  • Serotonin syndrome – a dangerous condition caused by rises in serotonin levels
  • Circulation problems in fingers and toes
  • A slowing and stunting of growth in children

The most common side effects of Adderall in clinical trials include:

  • Loss of appetite, weight loss
  • Insomnia
  • Abdominal pain
  • Changes in mood
  • Vomiting, nausea, and fever
  • Anxiety
  • Dry mouth
  • Headache, dizziness
  • Fast heart rate
  • Diarrhea, constipation
  • Asthenia
  • Urinary tract infections

More serious side effects of Adderall include

  • Serious cardiovascular events
  • Increase in blood pressure
  • Psychiatric adverse events – may cause treatment-emergent psychotic or manic symptoms in patients with no prior history, or worsening of symptoms in patients already suffering from psychosis
  • Long-term suppression of growth
  • Seizures
  • Peripheral vasculopathy, including Raynaud’s phenomenon
  • Visual disturbance
  • May exacerbate tics

These aren’t all the side effects Mydayis or Adderall can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to your physician or pharmacist.

Mydayis and Adderall drug interactions

Mydayis can interact with other medications. These include:

  • Other ADHD medications – amphetamine or dextroamphetamine
  • Monoamine oxidase inhibitor (MAOI) antidepressants – isocarboxazid, linezolid, metaxalone, methylene blue
  • Any other antidepressant medications – fluoxetine, paroxetine, duloxetine, venlafaxine
  • Any blood pressure medications
  • Any medications containing alcohol

Adderall can interact with other medications. These include:

  • MAOI antidepressants
  • Alkalinizing agents (GI antacids and urinary)
  • Acidifying agents (GI and urinary)
  • Adrenergic blockers
  • Antihistamines
  • Antihypertensives
  • Tricyclic antidepressants – norepinephrine, and meperidine

Mydayis and Adderall can interact with other medications. This can change how Mydayis and Adderall and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.

Mydayis and Adderall contraindications

You should not use Mydayis if you:

  • Are allergic to the active ingredients dextroamphetamine sulfate, amphetamine sulfate, dextroamphetamine saccharate, or amphetamine aspartate monohydrate
  • Are allergic to any of the other ingredients in Mydayis
  • Have had an allergic reaction to any other medications containing amphetamines
  • Are taking a medication called a monoamine oxidase inhibitor (MAOI), or have taken one in the last 14 days

Talk to your doctor before using Mydayis if you:

  • Are taking any of the medications that could interact with Mydayis
  • Have any heart problems
  • Have hypertension (high blood pressure)
  • Have any kidney problems
  • Have any mental health problems, like psychosis, bipolar disorder, or depression
  • Have any circulation problems in your fingers or toes
  • Have ever had a seizure
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should not use Adderall if you:

  • Are allergic to the active ingredient methylphenidate
  • Are allergic to any of the other ingredients in Concerta
  • Have known structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, coronary artery disease, or other serious heart problems
  • Have used a MAO inhibitor in the past 14 days, such as isocarboxazid, rasagiline, selegiline, or tranylcypromine
  • Are younger than 3 years old
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Adderall if you:

  • Have had problems with drug or alcohol abuse
  • Have a history of depression, mental illness, bipolar disorder, or suicidal thoughts or actions
  • Have glaucoma
  • Have an overactive thyroid
  • Have severe agitation
  • Have high blood pressure, heart disease or coronary artery disease
  • Have vascular disease
  • Have motor tics or Tourette’s syndrome
  • Suffer from seizures
  • Have liver or kidney disease
  • Blood circulation problems in your hands or feet
  • Are pregnant or are planning to become pregnant

Other drugs for ADHD

If you have any concerns about Mydayis or Adderall side effects, talk to your physician, or pharmacist for medical advice. They can discuss the best treatment options with you. Also inform your healthcare provider about any medical conditions, supplements, and over-the-counter meds you are taking. You are also encouraged to report side effects to the FDA: visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.