Keytruda Coupon & Prices

Is your Keytruda medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Keytruda medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Do you need help paying for Keytruda medication? Are you looking for an affordable solution to get your essential medicine? At NiceRx, we work with healthcare providers to help eligible individuals enroll in patient assistance programs for $49 per month*. 

We handle the full application process on your behalf. With our help, you could get access to the medications you need at an affordable price without any hassle and stress.  

Your monthly Keytruda cost savings if eligible

Eligible individuals for the Keytruda patient assistance program could get their prescription for a flat monthly fee of $49 per month. If eligible, you could save: 

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
100mg/4ml 1 vial$4,900.00$49.00$4,851.00

Am I eligible for the Keytruda patient assistance program?

At NiceRx we review each Keytruda assistance program application individually. The main eligibility factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Keytruda patient assistance program? 

To apply for the Keytruda patient assistance program, simply fill in our enrollment application

You will need to provide information on any medications you’re taking, including Keytruda. We’ll also ask for details about your healthcare provider and your household income, as well as your insurance details. This information is required by the pharmaceutical manufacturers who ship your medication.

We will review your application and handle the full application process for you if we determine that you are eligible for Keytruda assistance. Our service also includes requesting your Keytruda medication refills on your behalf for up to one year.

Is NiceRx a Keytruda coupons provider?

No, we are not a Keytruda coupon, a Keytruda discount card, or a Keytruda copay card. NiceRx is a service provider that helps eligible individuals access the Keytruda patient assistance program. We do not offer printable Keytruda manufacturer coupons, Keytruda discounts, free Keytruda samples, rebates, Keytruda savings cards, or trial offers. 

If you are looking for an affordable and stress-free way to access your essential medication, remember that when obtaining Keytruda through NiceRx, your total cost for the medication will always be $49 per month.

Can NiceRx help me get Keytruda if I have insurance? 

We may be able to help if your insurance company won’t pay for your Keytruda medication, you have a high copay or coinsurance responsibility, or you don’t have insurance.

How much is Keytruda with insurance?

Your healthcare plan will determine what you will need to pay for Keytruda with insurance. To understand the potential cost, contact your insurance provider or speak to a pharmacist. 

How much does Keytruda cost without insurance?

Keytruda prices without insurance will vary depending on the quantity you buy and the retailer you buy it from. As a guide, a pack with two 4 ml vials of 100 mg/ml Keytruda will cost close to $11,000.

What is Keytruda?

Keytruda is a medicine used to treat a range of cancers. You may be prescribed Keytruda if you have:

  • A skin cancer called melanoma
  • A skin cancer called Merkel cell carcinoma (MCC)
  • A lung cancer called non-small cell lung cancer (NSCLC)
  • A lung cancer called small cell lung cancer (SCLC)
  • Head and neck squamous cell cancer (HNSCC)
  • Classical Hodgkin lymphoma (cHL)
  • Mediastinal B-cell lymphoma (PMBCL)
  • A bladder and urinary tract cancer called urothelial carcinoma
  • A cancer called a microsatellite instability-high (MSI-H) or a mismatch repair deficient (dMMR) solid tumor
  • A stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma
  • A cancer called squamous cell carcinoma of the esophagus
  • Cervical cancer
  • A liver cancer called hepatocellular carcinoma
  • A kidney cancer called renal cell carcinoma (RCC)
  • A uterine cancer called endometrial carcinoma

Keytruda is often used when your cancer has spread, if it can’t be removed by surgery, it hasn’t responded to chemotherapy, and/or if your cancer tumors have certain abnormal genes. Rather than being a type of chemotherapy or radiotherapy, Keytruda is an immunotherapy that works with your immune system to help you fight your cancer. It’s given through a drip attached to one of your veins (intravenous), usually under the supervision of a doctor or nurse.

Cancer is a group of diseases that cause abnormal cell growths called tumors. The cells in your body can divide and grow. Usually, this is kept under control by your body, older cells are destroyed and replaced by new ones. However, mistakes in the DNA code inside cells can sometimes cause them to keep dividing and growing when they aren’t supposed to. This causes a tumor.

Cancerous tumors can keep growing, and they spread around your body, causing disruption and damage. They’re often treated using chemotherapy or radiotherapy to kill the tumors. But in some cases, these treatments may not be effective or may not be suitable for your cancer. In these instances, Keytruda may be a better option. It can be used alone, or it can be used alongside other treatments like chemotherapy or radiotherapy.

Keytruda active ingredients

The active ingredient in Keytruda is called pembrolizumab. It works by helping your immune system to fight cancerous tumors.

Some cancerous tumors protect themselves from your immune system. They produce a protein called programmed cell death protein 1 (PD-1). This protein forms on the outside of the tumor and it turns your immune system cells off. This stops your immune system from attacking and destroying the tumor. But pembrolizumab removes this protection. It attaches itself to the PD-1 proteins and stops them from working. This allows your immune system to fight the cancerous tumor.

Keytruda side effects & Keytruda drug interactions

The most common side effects caused by Keytruda include:

  • Headaches
  • A cough
  • Shortness of breath
  • Stomach pain
  • Diarrhea
  • Constipation
  • Nausea
  • Vomiting
  • A fall in your red blood cells
  • A fall in your white blood cells
  • Reduced thyroid activity
  • Feeling less hungry
  • Feeling tired and weak
  • Dizziness
  • Itching
  • A skin rash
  • Muscle pain
  • Pain in your bones
  • Joint pain

In rare instances, Keytruda can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • Severe infusion reactions,
  • Rejection of a transplanted organ

Keytruda fights cancer by helping your immune system to target cancerous tumors. It can sometimes cause your immune system to attack normal organs and tissue as well. This can damage your organs and tissue, and if this damage becomes severe, it may be life-threatening. 

You should make yourself aware of the symptoms of organ and tissue damage so you can seek medical attention if you develop them. They include:

  • Lung problems (pneumonitis) – chest pain, shortness of breath, a new or worse cough
  • Intestinal problems (colitis) – diarrhea or more bowel movements than usual, stomach tenderness and pain, stools that are black, sticky, or have blood or mucus in them
  • Liver problems (hepatitis) – pain on the right side of your stomach, a yellowing of your skin or the whites of your eyes, dark urine, bruising or bleeding more easily than normal
  • Kidney problems – changes in the amount or color of your urine
  • Hormone gland problems (particularly the thyroid, pituitary, adrenal glands, and pancreas) – weight loss or weight gain, feeling more hungry or thirsty, increased sweating, a rapid heartbeat, feeling cold, hair loss, feeling very weak, dizziness or fainting, headaches that will not go away
  • Skin problems – itching, rashes, peeling, sores, and ulcers in your mouth, nose, throat, or genital area

You may also have problems with other organs and tissues, including:

  • Changes in eyesight
  • Severe muscle weakness
  • Severe or persistent muscle or joint pains
  • Swollen lymph nodes 

Your doctor will assess your risk of side effects against the benefits of taking Keytruda. 

Keytruda can interact with other medications. When this happens Keytruda and the other medications may not be as effective. Certain side effects can also become more likely. Tell your prescribing physician about all drugs you’re taking, including vitamins and dietary supplements, particularly any medications that affect your immune system, like corticosteroids.

Keytruda warnings & precautions

Don’t take Keytruda if you:

  • Are allergic to the active ingredient pembrolizumab
  • Are allergic to any of the other ingredients in Keytruda (these will be listed in the leaflet which comes with the medication)

Talk to your doctor before taking Keytruda if you:

  • Are taking any of the medications that could affect your immune system and interact with Keytruda
  • Have an autoimmune disease, like Crohn’s disease, ulcerative colitis, or lupus
  • Have pneumonia or inflammation of your lungs (pneumonitis)
  • Were previously given a medication called ipilimumab and you experienced serious side effects
  • Have had an allergic reaction to other monoclonal antibody therapies
  • Have had any liver problems or have liver damage
  • Have had any kidney problems or have kidney damage
  • Have HIV or AIDS
  • Have had an organ transplant
  • Have had a bone marrow transplant that used donor stem cells
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

You should seek medical attention after taking Keytruda if you:

  • Show signs of a serious allergic reaction, like itching, a skin rash, shortness of breath, dizziness and fainting, sweating, a fast pulse, swelling of your face, throat, and other parts of your body like your hands and feet 
  • Show signs of organ or tissue damage (see above)

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.