Kyleena Coupon & Prices

Is your Kyleena medication too expensive?

Get notified when Kyleena medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Your monthly Kyleena cost savings if eligible

If you are eligible for the Kyleena patient assistance program, the cost of your medication will be free. We only charge $49 a month, per medication, to cover our service fees. You could receive your Kyleena prescription for just $49 a month, regardless of the retail price of your medication.

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
19.5mg 1 device$1,100.00$49.00$1,051.00

Am I eligible for the Kyleena patient assistance program?

We will review your application to determine whether you are eligible for the Kyleena patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Kyleena patient assistance program?

We make it as easy as possible to apply for the Kyleena patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Kyleena. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Kyleena assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Kyleena patient assistance program, and we will automatically request your Kyleena medication refills for up to 1 year.

Is NiceRx a Kyleena coupons provider?

We are a service provider that helps eligible individuals access the Kyleena patient assistance program. That means that we do not offer printable Kyleena manufacturer coupons, Kyleena discounts, or free Kyleena samples. We are not a Kyleena coupon provider or Kyleena discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Kyleena if I have insurance?

We may be able to help you to access Kyleena patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Kyleena medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much is Kyleena with insurance?

The cost of Kyleena with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

How much does Kyleena cost without insurance?

Kyleena prices without insurance will vary depending on where you buy it. As a guide, Kyleena intrauterine device 19.5 mg usually costs $1,053 for 1 device. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

What is Kyleena?

Kyleena contains the active ingredient levonorgestrel and is manufactured by Bayer. Bayer also manufactures alternative intrauterine devices such as Mirena and Skyla. All three of these devices are effective birth control methods. Kyleena is FDA-approved for birth control to prevent pregnancy for up to 3 to 6 years. Levonorgestrel is a synthetic progestin hormone and does not contain estrogen. Levonorgestrel is often used in birth control pills.

Kyleena is a T-shaped plastic intrauterine device (IUD) inserted through the vagina and placed into the uterus. It will be inserted by a healthcare professional. The Kyleena IUD device releases levonorgestrel into the uterus, causing changes in your cervix and uterus. Kyleena may be used alone or with other medications. It is important to understand that Kyleena should not be used for emergency contraception. Your healthcare provider can help you decide which birth control options are best for you and if an IUD is right for you, and if so, which one is best, taking into account your medical history. Kyleena does not protect against HIV or STIs (sexually transmitted infections).

Kyleena active ingredients

How exactly Kyleena and its release of levonorgestrel (LNG) within the uterus has a contraceptive effect has not been shown clearly. It is thought that Kyleena and similar LNG products have several methods of action. These include:

  • Thickening of the cervical mucus, which makes it more difficult for the sperm to pass into the uterus
  • Preventing sperm from maturing into sperm that are able to fertilize an egg
  • Making it more difficult for the sperm to survive in the uterus
  • To alter the lining of the uterus wall (endometrium)

Its effects are completely reversible, and your fertility rapidly returns – you can become pregnant as soon as Kyleena is removed.

This device can move out of place or come out by itself. If it comes out contact your healthcare professional immediately and use backup birth control such as condoms and spermicide to prevent pregnancy until you are advised otherwise.

Kyleena side effects

The most common side effects of Kyleena or adverse events include:

  • Pelvic pain
  • Ovarian cysts
  • Vaginal itching or infection
  • Missed, irregular menstrual periods (especially during the first 3 to 6 months), heavy bleeding, or changes in your bleeding patterns
  • Temporary pain, bleeding, or dizziness during insertion of the IUD
  • Stomach pain, nausea, vomiting, bloating
  • Headache, migraine
  • Depression, mood changes
  • Back pain
  • Breast pain or tenderness
  • Weight gain
  • Acne
  • Changes in hair growth
  • Loss of interest in sex
  • Puffiness in your face, hands, ankles, or feet

In rare instances, Kyleena can cause more serious side effects. These can include:

  • Severe infection or sepsis (a rare but life-threatening infection) can occur within the first few days
  • Pain during sexual intercourse
  • An ectopic pregnancy (pregnancy not in the uterus) – if this should occur remove the intrauterine system as leaving it in place can increase the risk of spontaneous abortion and preterm labor
  • Increased risk of intrauterine pregnancy
  • Perforation – the intrauterine device may go into the wall of the uterus or through the wall of the uterine cavity
  • Severe cramps or abdominal pain
  • Severely dizzy or lightheaded
  • Confusion, vision problems, sensitivity to light
  • Heavy vaginal bleeding, vaginal sores, unusual vaginal discharge
  • Pale skin, weakness, easily bruised or bleeding, fever, chills, or other signs of infection
  • Yellowing of the skin or eyes (jaundice)
  • Symptoms of a stroke or heart attack, such as sudden numbness or weakness, severe headache, or chest pain.

Your doctor will assess the benefits of using Kyleena against your risk of possible side effects.

Kyleena drug interactions

Kyleena can interact with other medications which can affect your blood levels of levonorgestrel and make this form of birth control less effective. These include:

  • Antivirals – amprenavir, boceprevir, fosamprenavir, telaprevir
  • Anticancer treatment – brigatinib, dabrafenib, encorafenib, pexidartinib
  • Anticonvulsants – carbamazepine, phenobarbital, phenytoin, felbamate
  • Etretinate – for the treatment of severe psoriasis
  • St. Johns wort

This list is not exhaustive and other drugs may interact with Kyleena. Call your doctor for further medical advice.

Kyleena contraindications

You should not use Kyleena if you:

  • Are allergic to the active ingredient levonorgestrel
  • Are allergic to any of the other ingredients in Kyleena
  • Have abnormal vaginal bleeding
  • Have an untreated pelvic or genital infection
  • Have endometriosis or a serious pelvic infection called pelvic inflammatory disease (PID) after a pregnancy or abortion in the last 3 months
  • Have had PID in the past unless you have had a normal pregnancy after the infection went away
  • Have cervix, or uterine cancer
  • Have breast cancer or any other cancer sensitive to progestin, now or in the past
  • Have uterine fibroid tumors
  • Have liver disease or a liver tumor
  • Have a weak immune system due to conditions such as AIDS or leukemia
  • If you have another IUD device in place
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Kyleena if you:

  • Are taking any of the medications that could interact with Kyleena
  • Have or have ever had high blood pressure, heart problems, or a stroke
  • Have any bleeding problems
  • Suffer from migraines or headaches
  • Have a vaginal or pelvic infection, or have a sexually transmitted disease
  • Are breastfeeding or are planning to breastfeed – Kyleena is unlikely to affect the quality or amount of your breast milk or the health of your nursing baby. However, a small number of cases of a reduction in milk production have been reported

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.