Skyla Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Skyla cost savings if eligible

With our assistance, you could access the Skyla patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
13.5mg 1 device$875.00$49.00$826.00

Am I eligible for Skyla patient assistance?

We review each Skyla enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Skyla patient assistance program?

Our process makes it as easy as possible to apply for the Skyla patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Skyla. You must also provide details about your healthcare provider, your insurance plan, and your household income. This is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Skyla coupons provider?

NiceRx is not a Skyla coupon, Skyla discount card, or Skyla copay card provider. We do not offer Skyla manufacturer coupons, Skyla discounts, rebates, Skyla savings cards, trial offers, or free Skyla samples. We are a service provider that helps eligible individuals access the Skyla patient assistance program.

Can NiceRx help me get Skyla if I have insurance?

NiceRx may be able to help you get Skyla if:

  • You have a high copay or coinsurance responsibility for Skyla
  • Your insurance company will not pay for your Skyla prescription
  • Your healthcare plan does not cover Skyla medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much is Skyla with insurance?

The cost of Skyla with insurance will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

How much does Skyla cost without insurance?

Skyla prices without insurance will vary depending on the pharmacy you buy it from. Prices will also vary by retailer. As a guide, Skyla 13.5 mg will cost around $880 for 1 device.

What is Skyla?

Skyla contains the prescription drug levonorgestrel and is manufactured by Bayer. Bayer also manufactures alternative intrauterine devices such as Mirena and Kyleena. All three of these intrauterine devices are effective birth control methods. Skyla is FDA (Food and Drug Administration)-approved for birth control to prevent pregnancy for up to 3 years. It is also indicated to treat heavy menstrual bleeding in women who prefer intrauterine contraception as their choice of contraception. Levonorgestrel is a synthetic progestin hormone and does not contain estrogen. Levonorgestrel is often used in birth control pills.

The Skyla IUD is inserted through the vagina and placed into the uterus by a healthcare professional. The device is usually inserted within 7 days after the start of a menstrual period. The Skyla IUD device releases levonorgestrel into the uterus, causing changes in your cervix and uterus. It is important to understand that Skyla should not be used for emergency contraception. Your healthcare provider can help you decide which birth control options are best for you and if an IUD is right for you, and if so, which one is best, taking into account your medical history. Skyla does not protect against HIV or STIs (sexually transmitted infections).

Skyla active ingredients

How exactly Skyla and its release of levonorgestrel (LNG) within the uterus has a contraceptive effect has not been shown clearly. It is thought that Skyla and similar LNG products have several methods of action. These include:

  • Thickening of the cervical mucus, which makes it more difficult for the sperm to pass into the uterus
  • Preventing sperm from maturing into sperm that are able to fertilize an egg
  • Making it more difficult for the sperm to survive in the uterus
  • To alter the lining of the uterus wall (endometrium)

Its effects are completely reversible, and your fertility rapidly returns – you can become pregnant as soon as Skyla is removed.

This device can move out of place or come out by itself. If it comes out contact your healthcare professional immediately and use backup birth control such as condoms and spermicide to prevent pregnancy until you are advised otherwise.

Skyla side effects

The most common side effects caused by Skyla include:

  • Pelvic pain
  • Ovarian cysts
  • Vaginal itching or infection
  • Missed or irregular menstrual periods (especially during the first 3 to 6 months), heavy bleeding, or changes in your bleeding patterns
  • Temporary pain, bleeding, or dizziness during insertion of the IUD
  • Stomach pain, nausea, vomiting, bloating
  • Headache, migraine
  • Depression, mood changes
  • Back pain
  • Breast pain tenderness
  • Weight gain
  • Acne
  • Changes in hair growth
  • Loss of interest in sex
  • Puffiness in your face, hands, ankles, or feet

In rare instances, Skyla can cause more serious side effects. These can include:

  • Severe infection or sepsis (a rare but life-threatening infection) can occur within the first few days
  • Pain during sexual intercourse
  • An ectopic pregnancy (pregnancy not in the uterus) – if this should occur remove the intrauterine system as leaving it in place can increase the risk of spontaneous abortion and preterm labor
  • Risk of intrauterine pregnancy
  • Perforation – the intrauterine device may go into the wall of the uterus or through the wall of the uterine cavity
  • Severe cramps or abdominal pain
  • Severely dizzy or lightheaded
  • Confusion, vision problems, sensitivity to light
  • Heavy vaginal bleeding, vaginal sores, unusual vaginal discharge
  • Pale skin, weakness, easily bruised or bleeding, fever, chills, or other signs of infection
  • Yellowing of the skin or eyes (jaundice)
  • Symptoms of a stroke or heart attack, such as sudden numbness or weakness, severe headache, or chest pain.

Your doctor will assess the benefits of using Skyla against your risk of side effects.

Skyla drug interactions

Skyla can interact with other medications which can affect your blood levels of levonorgestrel and make this form of birth control less effective. These include:

  • Antivirals – amprenavir, boceprevir, fosamprenavir, telaprevir
  • Anticancer treatment – brigatinib, dabrafenib, encorafenib, pexidartinib
  • Anticonvulsants – carbamazepine, phenobarbital, phenytoin, felbamate
  • Etretinate – for the treatment of severe psoriasis
  • Herbal products – St John’s wort

This list is not exhaustive and other drugs may interact with Skyla. Call your doctor for further medical advice.

Skyla contraindications

You should not use Skyla if you:

  • Are allergic to the active ingredient levonorgestrel
  • Are allergic to any of the other ingredients in Skyla
  • Have abnormal vaginal bleeding
  • Have an untreated pelvic or genital infection
  • Have endometriosis or a serious pelvic infection called pelvic inflammatory disease (PID) after a pregnancy or abortion in the last 3 months
  • Have had PID in the past unless you have had a normal pregnancy after the infection went away
  • Have breast cancer or any other cancer sensitive to progestin, now or in the past
  • Have cervix or uterine cancer
  • Have uterine fibroid tumors
  • Have liver disease or a liver tumor
  • Have a weak immune system due to conditions such as AIDS or leukemia
  • If you have another IUD device in place
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Skyla if you:

  • Are taking any of the medications that could interact with Skyla
  • Have or have ever had high blood pressure, heart problems, or a stroke
  • Have any bleeding problems
  • Suffer from migraines or headaches
  • Have a vaginal or pelvic infection, or have a sexually transmitted disease
  • Are breastfeeding or are planning to breastfeed – Skyla is unlikely to affect the quality or amount of your breast milk or the health of your nursing baby. However, a small number of cases of a reduction in milk production have been reported

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.