Saphris Coupon & Prices

Is your Saphris medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Saphris medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Is your Saphris medication too expensive? Are you struggling to afford your essential medicine? At NiceRx we may be able to help. With our assistance, you may be able to get your Saphris for just $49 per month.*

By working directly with your healthcare provider, we seek to enroll you in assistance programs. Each step of the application process is handled by us to reduce the pressure and stress of trying to secure affordable medication.  

Your monthly Saphris cost savings if eligible

If you are eligible for and accepted onto the patient assistance program you could receive your Saphris prescription for a flat fee of just $49 per month, every month. This could save you:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
2.5mg 60 tablets
5mg 60 tablets
10mg 60 tablets

Am I eligible for the Saphris patient assistance program?

At NiceRx, we evaluate each Saphris assistance program application individually. Often the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Saphris patient assistance program? 

Our application process is simple and straightforward. Begin by completing our enrollment application. Essential information we need includes any medications you’re taking, including Saphris, as well as details about your healthcare provider, insurance, and your household income. 

If we determine that you may be eligible for Saphris assistance, we’ll handle the application process and help to enroll you in the Saphris patient assistance program. Once enrolled in the program, we’ll also request refills of your medication on your behalf for up to a year.

Is NiceRx a Saphris coupons provider?

NiceRx is a service provider that helps eligible individuals access the Saphris patient assistance program. Our service helps individuals receive their medication refills if they are accepted for the program. We don’t offer printable Saphris manufacturer coupons, Saphris discounts, Saphris savings cards, or free Saphris samples. NiceRx is also not a Saphris coupon, a Saphris discount card, or a Saphris copay card.

Remember by applying for the patient assistance program, you may be able to secure cheap Saphris on an ongoing basis without any hassle and stress. 

Can NiceRx help me get Saphris if I have insurance? 

Every application for the Saphris patient assistance program is considered individually. We may be able to help you if your insurance company won’t pay for your Saphris medication, you have a high copay or coinsurance responsibility, or you don’t have insurance. 

How much is Saphris with insurance?

The cost of Saphris will vary by the healthcare plan. To find out your exact costs with your current insurance, contact your healthcare provider or pharmacist. 

How much does Saphris cost without insurance?

Saphris prices without insurance will vary depending on where you buy it, the strength of the tablets (2.5 mg, 5 mg, or 10 mg), and the number of tablets per pack (60 or 100). As a guide, you can expect to pay over $1,200 for a pack of 60 Saphris 2.5 mg tablets, and up to $2,500 for a 100 pack of 10 mg tablets. With NiceRx you’ll always pay a flat monthly fee of $49.

What is Saphris?

Saphris is an antipsychotic medication. It’s prescribed to treat moderate to severe manic episodes (mania) in adults who have schizophrenia or bipolar disorder. You take Saphris by placing a tablet under your tongue where it dissolves into your bloodstream.

Bipolar disorder, previously called manic depression, is a mental health condition. It causes both periods of depression and periods of elevated mood. If the elevated moods are severe, they’re called mania. Mania is a heightened physical and emotional state. People experience mania differently, you may have high energy levels, sleep less, have floods of ideas and speech, and engage in impulsive behaviors. You can feel euphoric, or alternatively you can feel irritable, which can lead to anxiety and violence.

Schizophrenia is a mental health condition where you experience episodes where it’s difficult to understand what’s real and what isn’t (psychosis). These episodes can cause delusions, hallucinations, disordered thinking, and also mania. 

Saphris helps to treat mania in people with schizophrenia or bipolar disorder by reducing the intensity of manic symptoms. It does this by inhibiting activity in certain areas of your brain, helping to normalize brain function.

Saphris active ingredients

The active ingredient in Saphris is asenapine. Once Saphris is in your bloodstream, asenapine passes through the blood-brain barrier into your brain. It then attaches itself to areas on your neurons called receptors.

Receptors help your neurons communicate with each other. Substances produced in your brain called neurotransmitters attach to the receptors causing them to send signals to other neurons. But asenapine stops this happening. When it binds to a receptor it blocks it, meaning it can’t be stimulated by neurotransmitters to send signals.

Blocking receptors reduces the number of signals sent through your brain. This helps to normalize brain activity, improving the symptoms of mania caused by schizophrenia and bipolar disorder.

Saphris side effects & Saphris drug interactions

The most common side effects caused by Saphris affect around 1 in 10 people. They include sleepiness, anxiety, increased appetite and weight gain, changes in taste, nausea, fatigue, muscle contractions, and tremors.

Saphris can cause more severe side effects in rare cases. These include allergic reactions to the medication, convulsions, seizures, sudden increase in body temperature, sudden falls in blood pressure, and increased blood sugar levels. Your physician will assess your suitability for Saphris and your risk of side effects. Speak to them if you have any concerns about side effects. 

Medications that are known or thought to interact with Saphris include:

  • Antidepressant medications, particularly fluvoxamine, paroxetine, or fluoxetine
  • Medicines for Parkinson’s disease, like levodopa
  • Medicines that lower blood sugar
  • Any other medications that affect brain activity, including alcohol

When medications interact, it can make them less effective and sometimes cause side effects to be worse. Make sure you tell your prescribing physician about all drugs you’re taking to be sure of potential interactions. This includes vitamins and dietary supplements.

Saphris warnings & precautions

Don’t take Saphris if you:

  • Are allergic to the active ingredient asenapine
  • Are allergic to any of the other ingredients in Saphris (listed in the leaflet which comes with the medication)
  • Are under 18 years of age

Talk to your physician before taking Saphris if you:

  • Have ever had a condition that causes high body temperature and muscle stiffness, such as neuroleptic malignant syndrome
  • Have difficulties controlling your core body temperature
  • Have ever experienced abnormal movements of the tongue or face (tardive dyskinesia)
  • Have heart disease
  • Have severe liver problems
  • Are diabetic or prone to diabetes
  • Have abnormally high levels of prolactin in your blood (hyperprolactinaemia)
  • Have Parkinson’s disease or dementia
  • Have epilepsy
  • Experience difficulties swallowing
  • Experience suicidal thoughts
  • Are pregnant or trying to become pregnant
  • Are breastfeeding or plan to breastfeed

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.