Tnkase Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Tnkase cost savings if eligible

With our assistance, you could access the Tnkase patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Tnkase patient assistance?

We review each Tnkase enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Tnkase patient assistance program?

Our process makes it as easy as possible to apply for the Tnkase patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Tnkase, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Tnkase coupons provider?

NiceRx is not a Tnkase coupon, Tnkase discount card, or Tnkase copay card provider. We do not offer Tnkase manufacturer coupons, Tnkase discounts, rebates, Tnkase savings cards, trial offers, or free Tnkase samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Tnkase
  • Your insurance company will not pay for your Tnkase prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Tnkase cost without insurance?

Without insurance, Tnkase costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Tnkase intravenous powder for injection 50 mg will cost around $7,000 for 1 powder for injection.

How much does Tnkase cost with insurance?

The copay for Tnkase will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Tnkase?

TNKase is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Genentech, Inc. TNKase is a bioengineered variant of Activase (Alteplase, recombinant), which is a recombinant DNA-derived version of naturally occurring tissue plasminogen activator (tPA). TNKase is a thrombolytic drug. TNKase is used to prevent death in people who have had a heart attack (acute myocardial infarction).

What doses of Tnkase are available?

Tnkase is available in injection form, in the following doses: Each vial contains 52.5 mg and will deliver 50 mg of Tenecteplase.

TNKase is the most fibrin-specific molecule and can be delivered as a single bolus intravenous injection. It is given as an infusion directly into a vein. A healthcare provider will give you this injection.

Please read all the instructions completely before beginning reconstitution and administration and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Tnkase active ingredients

The active ingredient of Tnkase is tenecteplase.

Tnkase side effects

The most common side effects of Tnkase in clinical trials include:

  • Swelling, rapid weight gain
  • Little or no urinating
  • Slow heart rate
  • Shortness of breath, feeling faint
  • Sudden severe back pain
  • Muscle weakness, numb feeling in your arms or legs
  • increased blood pressure
  • Pancreatitis

In rare instances, Tnkase can cause more serious side effects. These can include:

  • Coronary thrombolysis may result in arrhythmias associated with reperfusion
  • Easy bruising or bleeding
  • Dark stools, coughing up blood or vomit that looks like coffee grounds
  • Sudden numbness or weakness (especially down one side of the body, sudden severe headache, slurred speech, problems with vision or balance
  • Cholesterol embolism
  • Increased risk of thromboembolic events in patients with a high likelihood of left heart thrombus, such as patients with mitral stenosis or atrial fibrillation

Your doctor will assess the benefits of using Tnkase against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Tnkase to the FDA. Visit, or call 1-800-FDA-1088.

Tnkase drug interactions

Tnkase can interact with other medications. These include:

  • Heparin, vitamin K antagonists, aspirin, dipyridamole, GP IIb/IIIa inhibitors
  • Interference with coagulation tests

This list is not exhaustive and other prescription drugs may interact with Tnkase.

Tnkase contraindications

You should not use Tnkase if you:

  • Are allergic to the active ingredient tenecteplase
  • Have hypersensitivity to any of the other ingredients in Tnkase
  • Have active internal bleeding
  • Have severe uncontrolled hypertension
  • Have a genetic disorder affecting the blood vessels in your brain
  • Have intracranial neoplasm, arteriovenous malformation, or aneurysm
  • Have a bleeding or blood clotting disorder
  • Have a history of cerebrovascular accident
  • Have had brain or spinal cord injury or surgery within the past 2 months
  • Have known bleeding diathesis

Talk to your doctor before using Tnkase if you:

  • Are taking any of the medications that could interact with Tnkase
  • Have had a stroke
  • Have high blood pressure, heart problems, bacterial endocarditis
  • Have a serious injury or have had recent major surgery
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Have cerebrovascular disease
  • Have recent gastrointestinal or genitourinary bleeding
  • Have acute pericarditis
  • Have hemostatic defects, including those secondary to severe hepatic or renal disease
  • Have severe hepatic dysfunction
  • Have diabetic hemorrhagic retinopathy or other hemorrhagic ophthalmic conditions
  • Have septic thrombophlebitis or occluded AV cannula at a seriously infected site
  • Are of advanced age
  • Are receiving oral anticoagulants – warfarin sodium
  • Have any other conditions in which bleeding would be a hazard or would be particularly difficult to manage because of its location

Tnkase generic

Tnkase is the trademark brand name for tenecteplase manufactured by Genentech, Inc. A generic version of tenecteplase is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Tnkase savings through NiceRx.

Related medications

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.