$50 off your first month of Compounded Semaglutide · start your free assessment →$50 off first month of Compounded Semaglutide →
Weight loss · GLP-1

Compounded Semaglutide Injection

A once-weekly GLP-1 injection that helps regulate appetite and blood sugar, prescribed by a provider licensed in your state and delivered to your door.Plans from $89.58/month

Takes about 2 minutes · free to complete

Compounded drugs are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription required.

Compounded Semaglutide
Free & discreet deliveryPlain packaging, typically arriving within 3–5 business days of provider approval.
No insurance requiredSimple cash-pay care with no insurance claims.
Licensed cliniciansEvery plan is reviewed by a healthcare provider licensed in your state.
Licensed U.S. pharmaciesMedications are dispensed by licensed U.S. pharmacy partners.
About this treatment

One weekly injection, working with your body.

You feel full sooner and stay full longer, so eating less stops feeling like a fight. Semaglutide gets you there by working with a hormone your gut already releases after eating (slowing digestion, steadying blood sugar and turning down appetite) so smaller portions feel like enough. The compounded form is prepared for your prescription by a state-licensed U.S. pharmacy.

Who it may suitAdults with a BMI of 27+, confirmed in your clinical review, never by BMI alone.
How it's takenTypically one self-administered injection per week, with dosing and schedule set and adjusted by your clinician.
What's managed for youTitration schedule, dose changes, refills and check-ins. Your plan adapts as you respond.
See plans and pricing →
Typical dosing schedule
  1. 0.25mgMonth 1
  2. 0.5mgMonth 2
  3. 1.0mgMonth 3
  4. 1.75mgMonth 4
  5. 2.5mgMonth 5+
Your monthly price doesn't change as your dose increases

Read the semaglutide dosage chart →

This is the standard semaglutide dosing schedule.

Actual dosing is personalized to each patient. Your provider determines the dose and titration that's most appropriate for you, which may differ from what's shown. Your clinician adjusts in steps, then you settle at the dose that balances results and comfort.

Patient stories

Real people. Real experiences.

Trusted by NiceRx patients
★★★★★

“I've lost 30 pounds over six months. NiceRx made the process smooth and stress-free — from easy access to my medication to genuinely helpful support.”

Nechelle W. · Verified NiceRx patient
★★★★★

“I'd recommend NiceRx to anyone not covered for weight-loss injections. I always had my questions answered promptly and felt I was in good hands.”

Rosemary R. · Verified NiceRx patient
★★★★★

“Anytime I needed to talk to the doctor or pharmacist, they were there for me. My experience has been excellent — I've recommended them to family.”

Sheree C. · Verified NiceRx patient

See all patient stories & reviews →

*Real users that are paid for appearance. Individual results may vary.

Compounded Semaglutide kit
What arrives

Everything you need, in one discreet box.

  • Your prescribed medicationDispensed by a state-licensed U.S. pharmacy, in the quantity your provider prescribes.
  • Temperature-controlled packagingShipped to keep your medication at the right temperature in transit.
  • Single-use syringesFine-gauge insulin syringes: one for each weekly dose.
  • Step-by-step instructionsPlus support by phone or email, and a follow-up visit with your provider whenever you need one.

Your vial, insulin syringes and a step-by-step injection guide arrive together, in plain packaging. Kit contents may vary slightly by pharmacy partner.

Pricing

Simple, all-inclusive pricing.

Choose how long you commit, the longer the plan, the lower your monthly price.

Start your assessmentYour selected plan carries into the assessment
Nothing charged until prescribedYour card is authorized, not charged, until a licensed clinician approves your plan.
Switch without losing progressYou're not reset to the lowest dose. Your provider continues where it's clinically appropriate.
No membership, shipping or hidden feesEvaluation, treatment and delivery are all included.

Each plan covers a 4-, 12-, 24- or 48-week supply. Multi-month plans ship in one or more deliveries across your plan based on your dosing; your provider confirms your schedule after approval.

Every plan includes

  • ✓ Clinician evaluation and ongoing dose management. Your provider sets and adjusts your dose over time.
  • ✓ Your medication, dispensed by a state-licensed U.S. pharmacy, with the supplies to use it.
  • ✓ Free, discreet delivery, temperature-controlled, typically arriving within 3–5 business days of provider approval.

Plans start from the monthly prices shown and vary by treatment. Prescription treatments are only provided after an online evaluation by a licensed healthcare professional who determines whether treatment is appropriate. Compounded medications are not FDA-approved.

Tirzepatide vs. semaglutide

Two GLP-1 options, in plain terms.

Compounded tirzepatide

Acts on GLP-1 and GIP receptors. Weekly injection, 2.5–15 mg. Often chosen when a stronger effect is wanted, or when semaglutide hasn't done enough.

From $145.75/month

See tirzepatide →

Compounded semaglutide

Acts on the GLP-1 receptor. Weekly injection, 0.25–2.5 mg. The established option most people start with, and the lower monthly price.

From $89.58/month

You don't have to decide alone. Tell us your goals and history in the assessment. Your clinician recommends the option that fits, and can switch you later if it isn't working.

How it works

From assessment to your door.

1

Complete your assessment

Tell us about your health, goals and preferences. About 2 minutes, free to complete.

2

Clinician review

Your health history is reviewed and treatment is confirmed only if it's appropriate for you.

3

Get your personalized plan

If appropriate, your clinician prescribes a treatment matched to your needs.

4

Delivered + ongoing care

Your medication is dispensed and shipped discreetly, with ongoing support when you need it.

Start your assessment

Your consultation is free. Takes about 2 minutes. You're only charged if a clinician prescribes treatment and you choose to begin.

Medical & pharmacy

Real medical care, delivered online.

Your treatment is prescribed by a licensed provider and dispensed by state-licensed U.S. pharmacies. Nothing ships without clinical review.

Licensed clinicians

Reviewed by a provider licensed in your state.

Clinical review before dispensing

No prescription is filled without it.

State-licensed U.S. pharmacies

Compounded and dispensed under state pharmacy regulation.

Private and secure

Your health information is encrypted and never sold.

Verify LegitScript approval for www.nicerx.comCompounded in the U.S.A. by state-licensed pharmacy partners

Compounded medications are prepared by state-licensed compounding pharmacies and are not FDA-approved. A licensed provider determines whether a compounded treatment is appropriate for you.

Safety information

Know this before you start.

Common side effectsNausea, constipation and fatigue are most common, usually strongest in early weeks and often manageable with clinician-guided titration.
Who should not take semaglutidePeople with a personal or family history of medullary thyroid carcinoma or MEN 2, and those pregnant, planning pregnancy or breastfeeding.
Tell your clinicianAbout all medications and conditions, especially diabetes treatment, pancreatitis history or gallbladder disease.

Compounded semaglutide is prepared by state-licensed compounding pharmacies and is not FDA-approved. This is not a complete list of risks. Your clinician reviews full safety information with you, and treatment is only prescribed where appropriate.

FAQ

Common questions.

How do I take it?
Most patients take one small self-administered injection per week, though your provider may personalize how often you take it. Your welcome kit includes everything you need, and your care team walks you through the first one.
What if semaglutide isn't right for me?
Your clinician may recommend a different dose or treatment instead. The assessment covers all options. Your card is only authorized at checkout. It's charged only if a provider prescribes and you choose to begin; otherwise the authorization is voided.
Do I need insurance?
No. NiceRx is simple cash-pay care with no claims or prior authorizations. Monthly plans carry no commitment; longer plans are prepaid for a lower monthly price.
I'm switching from another provider: do I start at the lowest dose again?
Not necessarily. Tell us your current medication and dose in the assessment. Your clinician reviews it and decides whether to continue at your current dose or adjust. It's a clinical decision, not a reset.
What if I miss a dose?
Guidance depends on how many days have passed. Your care team gives you exact instructions in your plan, and you can message them any time. Don't double up without checking.
What are the most common side effects?
Nausea, reduced appetite, and digestive changes are most common, usually mild and most noticeable when a dose increases. Starting low and stepping up gradually is how your plan is designed to limit them.
Can I pause or cancel?
Monthly plans have no commitment. Cancel before your next billing date. Longer plans are prepaid for a lower monthly price; contact support about your options if your circumstances change.
How is this different from Ozempic® or Wegovy®?
Ozempic® and Wegovy® are FDA-approved brand-name semaglutide products. Compounded semaglutide is prepared for your prescription by a state-licensed compounding pharmacy; it is not FDA-approved and does not undergo FDA review. Your provider decides whether a compounded option is appropriate for you.
When might I see results?
Many people notice appetite changes within the first few weeks. Weight change is gradual and varies from person to person. Your provider tracks your response and adjusts your plan with you.
What if a dose increase is recommended?
Your provider adjusts your dose over time as needed. Your monthly price stays the same at every dose, so a recommended increase never changes what you pay.
Start today

Your plan starts with one assessment.

About two minutes to complete. A licensed clinician tells you what's appropriate for you.

Start your assessment
Free to complete · No insurance required · Cancel anytime