Trizivir Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Trizivir cost savings if eligible

With our assistance, you could access the Trizivir patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Trizivir patient assistance?

We review each Trizivir enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Trizivir patient assistance program?

Our process makes it as easy as possible to apply for the Trizivir patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Trizivir, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Trizivir coupons provider?

NiceRx is not a Trizivir coupon, Trizivir discount card, or Trizivir copay card provider. We do not offer Trizivir manufacturer coupons, Trizivir discounts, rebates, Trizivir savings cards, trial offers, or free Trizivir samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Trizivir
  • Your insurance company will not pay for your Trizivir prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Trizivir cost without insurance?

Without insurance, Trizivir costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Trizivir oral tablets (300 mg-150 mg-300 mg) will cost around $1,700 for 60.

How much does Trizivir cost with insurance?

The copay for Trizivir will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Trizivir?

Trizivir is an FDA (U.S. Food and Drug Administration) approved medication manufactured for ViiV Healthcare.

Trizivir is a combination of abacavir, lamivudine, and zidovudine, which are nucleoside analog HIV-1 reverse transcriptase inhibitors. It is indicated in combination with other antiretroviral agents for the treatment of HIV infection in adults, adolescents, and children who weigh at least 88 lb (40 kg). It helps to decrease the amount of HIV in your body so your immune system can work better. This HIV treatment is recommended only when an NNRTI-based or a protease inhibitor-based regimen cannot or should not be used.

Trizivir can cause serious, life-threatening side effects. These include allergic reactions, a buildup of lactic acid in the blood (lactic acidosis), liver problems, muscle pain or weakness (myopathy), and blood disorders such as extremely reduced numbers of red blood cells (severe anemia) or reduced numbers of white blood cells (neutropenia).

Patients who carry the HLA-B*5701 allele are at a higher risk of experiencing a hypersensitivity reaction to abacavir. Never restart Trizivir or any other abacavir-containing product following a hypersensitivity reaction.

Hematologic toxicity, including neutropenia and anemia, has been associated with the use of zidovudine. Symptomatic myopathy is associated with prolonged use of zidovudine. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported.

Severe acute exacerbations of hepatitis B have been reported in patients who are co-infected with hepatitis B virus (HBV) and human immunodeficiency virus (HIV-1) and have discontinued lamivudine.

What doses of Trizivir are available?

Trizivir is available in tablet form, in the following doses: 300 mg abacavir, 150 mg lamivudine, and 300 mg zidovudine.

Before initiating treatment, screen for the HLA-B*5701 allele. Adults and pediatric patients weighing at least 40 kg should take 1 tablet twice daily. Trizivir is a fixed-dose tablet and cannot be dose adjusted. It is not recommended in patients requiring dosage adjustment or patients with hepatic impairment.

You will need regular blood tests to check your blood cell counts while you are taking this medication. Always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Trizivir active ingredients

Trizivir tablets contain the following 3 synthetic nucleoside analogs, abacavir sulfate (Ziagen), lamivudine (Epivir), and zidovudine (Retrovir, or ZDV) with inhibitory activity against HIV-1. All 3 belong to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs).

Abacavir is an antiviral carbocyclic synthetic nucleoside analog, converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP). Lamivudine is a synthetic nucleoside analog, phosphorylated to its active 5′-triphosphate metabolite. Zidovudine is a synthetic nucleoside analog phosphorylated to its active 5′-triphosphate metabolite, zidovudine triphosphate (ZDV-TP).

Trizivir side effects

The most common side effects of Trizivir in clinical trials include:

  • Nausea, headache, malaise and fatigue, and nausea, vomiting, loss of appetite

In rare instances, Trizivir can cause more serious side effects. These can include:

  • Hepatic decompensation
  • Exacerbation of anemia
  • Immune reconstitution syndrome and redistribution/accumulation of body fat

Stop taking Trizivir and call your doctor at once if you have signs of an allergic reaction -fever, rash, nausea, vomiting, diarrhea, abdominal pain, stomach pain, extreme tiredness, body aches; shortness of breath, cough, sore throat.

Your doctor will assess the benefits of using Trizivir against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Trizivir to the FDA. Visit, or call 1-800-FDA-1088.

Trizivir drug interactions

Trizivir can interact with other medications. These include:

  • Methadone
  • Agents antagonistic with zidovudine
  • Hematologic/bone marrow suppressive/cytotoxic agents
  • Emtricitabine is similar to lamivudine and should not be taken with this medication

This list is not exhaustive and other prescription drugs may interact with Trizivir. Tell your doctor about other prescription and non-prescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take, especially interferon and ribavirin.

Trizivir contraindications

You should not use Trizivir if you:

  • Are allergic to the active ingredient abacavir, lamivudine, and zidovudine
  • Are allergic to any of the other ingredients in Trizivir
  • Are pregnant or are planning to become pregnant
  • Have the HLA-B*5701 allele
  • Have had prior hypersensitivity reactions to abacavir, lamivudine, or zidovudine
  • Have a moderate or severe hepatic impairment

Talk to your doctor before using Trizivir if you:

  • Are taking any of the medications that could interact with Trizivir
  • Are breastfeeding or are planning to breastfeed
  • Have liver disease (especially hepatitis B or C) or any other liver problems
  • Have bone marrow suppression
  • Have heart problems or risk factors such as diabetes, smoking, high blood pressure, high cholesterol, or kidney disease

Trizivir generic

Trizivir is the trademark brand name for abacavir, lamivudine, and zidovudine manufactured for ViiV Healthcare. A generic version of abacavir, lamivudine, and zidovudine is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Trizivir savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.