Zevalin Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Zevalin cost savings if eligible

The Zevalin patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Zevalin, regardless of the retail price.

Am I eligible for the Zevalin patient assistance program?

To find out if you are eligible for Zevalin assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zevalin patient assistance program?

Our application process aims to make it as easy as possible to apply for the Zevalin patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Zevalin.

NiceRx will review your application and determine whether you may be eligible for Zevalin assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Zevalin patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Zevalin.

Is NiceRx a Zevalin coupons provider?

NiceRx is a service provider that helps eligible individuals access the Zevalin patient assistance program. We do not offer trial offers or free Zevalin samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Zevalin coupons, discount cards, or Zevalin copay cards.

Can NiceRx help me get Zevalin if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Zevalin medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Zevalin cost without insurance?

Zevalin prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Y-90 Zevalin intravenous kit (3.2 mg/2 mL) typically costs $59,350 for 1 kit.

How much does Zevalin cost with insurance?

The copay for Zevalin will vary by the terms of your healthcare plan. To find out what you might need to pay for Zevalin with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Zevalin?

Zevalin is an FDA (U.S. Food and Drug Administration) approved medication. It is administered as part of the Zevalin therapeutic regimen for the treatment of patients with relapsed or refractory, low-grade or follicular B-cell non-Hodgkin’s lymphoma (NHL) previously untreated follicular NHL who achieve a partial or complete response to first-line chemotherapy.

Serious life-threatening infusion reactions, some fatal, may occur within 24 hours of rituximab infusion. Prolonged and severe cytopenias occur in most patients. Severe cutaneous and mucocutaneous reactions, some fatal, were reported with the Zevalin therapeutic regimen. Do not administer Y-90 Zevalin to patients with altered biodistribution. Do not exceed 32 mCi (1184 MBq) of Y-90 Zevalin.

What doses of Zevalin are available?

Zevalin is available in injection form, in the following doses: 2 mg per 2 mL, single-use vial.

Always speak with your healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Zevalin active ingredients

The active substance in Zevalin, ibritumomab, is a monoclonal antibody. It binds to the CD20 antigen. The CD20 antigen is expressed on pre-B and mature B lymphocytes and on > 90% of B-cell non-Hodgkin’s lymphomas (NHL). The CD20 antigen is not shed from the cell surface and does not internalize upon antibody binding.

The chelate tiuxetan, which tightly binds Y-90, is covalently linked to ibritumomab. The beta emission from Y-90 induces cellular damage by the formation of free radicals in the target and neighboring cancer cells.

Ibritumomab tiuxetan binding was seen on lymphoid cells of the bone marrow, lymph node, thymus, the red and white pulp of the spleen, and lymphoid follicles of the tonsil, as well as lymphoid nodules of other organs such as the large and small intestines.

Zevalin side effects

The most common side effects of Zevalin in clinical trials include:

  • Neutropenia (low white blood cells)
  • Leukopenia
  • Thrombocytopenia
  • Anemia (low red blood cells) – obtain complete blood counts (CBC) and platelet counts at least weekly
  • Infection
  • Asthenia
  • Musculoskeletal and gastrointestinal symptoms.

In rare instances, Zevalin can cause more serious adverse reactions. These can include:

  • Serious infusion reactions
  • Prolonged and severe cytopenias – do not treat patients with less than 25% lymphoma marrow involvement or impaired bone marrow reserve with Zevalin
  • Stop treatment with rituximab or Zevalin infusions if patients develop severe cutaneous, mucocutaneous reactions, Acute myelogenous leukemia (AML, a type of cancer of the blood), and Myelodysplastic syndrome (MDS)
  • Embryo-fetal toxicity

Your doctor will assess the benefits of using Zevalin against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zevalin to the FDA. Visit, or call 1-800-FDA-1088.

Zevalin drug interactions

  • Immunization – do not administer live viral vaccines to patients who recently received treatment
  • Monitor patients receiving medications that interfere with platelet function or coagulation more frequently for thrombocytopenia and bleeding

This list is not exhaustive and other prescription drugs may interact with Zevalin.

Zevalin contraindications

You should not use Zevalin if you:

  • Are allergic to the active ingredient ibritumomab tiuxetan
  • Are allergic to any of the other ingredients in Zevalin
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Zevalin if you:

  • Are taking any of the medications that could interact with Zevalin

Zevalin generic

Zevalin is the trademark brand name for ibritumomab tiuxetan. A generic version of ibritumomab tiuxetan may be available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zevalin savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.