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Zinplava Patient assistance program

Is your Zinplava medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Zinplava medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

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  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Zinplava cost savings if eligible

The Zinplava patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Zinplava, regardless of the retail price.

Am I eligible for the Zinplava patient assistance program?

To find out if you are eligible for Zinplava assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zinplava patient assistance program?

Our application process aims to make it as easy as possible to apply for the Zinplava patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Zinplava.

NiceRx will review your application and determine whether you may be eligible for Zinplava assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Zinplava patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Zinplava.

Is NiceRx a Zinplava coupons provider?

NiceRx is a service provider that helps eligible individuals access the Zinplava patient assistance program. We do not offer trial offers or free Zinplava samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Zinplava coupons, discount cards, or Zinplava copay cards.

Can NiceRx help me get Zinplava if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Zinplava medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Zinplava cost without insurance?

Zinplava prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Zinplava intravenous solution (25 mg/mL) typically costs $4,000 for 40 milliliters.

How much does Zinplava cost with insurance?

The copay for Zinplava will vary by the terms of your healthcare plan. To find out what you might need to pay for Zinplava with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Zinplava?

Zinplava is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. Zinplava is a human monoclonal antibody that binds to Clostridium difficile toxin B, indicated to reduce the recurrence of Clostridium difficile infection (CDI) in patients 18 years of age or older who are receiving antibacterial drug treatment of CDI and are at high risk for CDI recurrence.

Zinplava is not indicated for the treatment of c. difficile infection. Zinplava is not an antibacterial drug and should only be used with antibacterial drug treatment of CDI. The pediatric safety and efficacy of Zinplava in patients below 18 years of age have not been established.

What doses of Zinplava are available?

Zinplava is available in injection form, in the following doses: 1,000 mg/40 mL (25 mg/mL) solution in a single-dose vial.

The recommended dose is a single dose of 10 mg/kg as an intravenous infusion over 60 minutes. Dilute before IV infusion. Administer via a low-protein binding 0.2 micron to 5 microns in-line or add-on filter. See the full prescribing information for dilution and administration instructions.

Zinplava can be infused via a central line or peripheral catheter. Do not coadminister other drugs simultaneously through the same infusion line.

The safety and efficacy of repeat administration in patients with CDI have not been studied. Read all FDA-approved patient labeling/patient information, medication guides, and instruction sheets provided. Always speak with your healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Zinplava active ingredients

Bezlotoxumab mechanism of action is as a human monoclonal antibody that binds C. difficile toxin B. Bezlotoxumab does not bind to C. difficile toxin A.

Zinplava side effects

The most common side effects of Zinplava in clinical trials compared to placebo include:

  • Nausea
  • Pyrexia
  • Headache

In rare instances, Zinplava can cause more serious adverse reactions. These can include:

  • Heart Failure – more common in patients with a history of congestive heart failure (CHF). In patients with a history of CHF, treatment should be used when the benefit outweighs the risk

Your doctor will assess the benefits of using Zinplava against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Zinplava to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Zinplava drug interactions

Zinplava is eliminated by catabolism, no metabolic drug-drug interactions are expected.

Zinplava contraindications

You should not use Zinplava if you:

  • Are allergic to the active ingredient bezlotoxumab
  • Are allergic to any of the other ingredients in Zinplava
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Zinplava if you:

  • Are taking any of the medications that could interact with Zinplava
  • Are breastfeeding or are planning to breastfeed – Lactation risk summary. There is no information regarding the presence of bezlotoxumab in human milk, the effects on the breast-fed infant, or the effects on milk production

Zinplava generic

Zinplava is the trademark brand name for bezlotoxumab manufactured by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. A generic version of bezlotoxumab is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zinplava savings through NiceRx.

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.