Epclusa Coupon & Prices

Is your Epclusa medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Epclusa medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Have you been prescribed Epclusa and cannot afford the high cost? At NiceRx we may be able to assist you to get your Epclusa medication without the hassle and stress, at an affordable price. 

We help eligible individuals enroll in patient assistance programs for prescription medications by working alongside healthcare providers. This means that if you are eligible you may be able to get your Epclusa medication for just $49 per month*. We handle the full application process for you in a simple and stress-free way. 

Your monthly Epclusa cost savings if eligible

If we determine you are eligible, you could get your Epclusa prescription for a flat fee of just $49 per month. This flat fee covers the full cost of your Epclusa medicine and is the only fee that you will need to pay. You could save:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
400/100mg 28 tablets$25,600.00$49.00$25,551.00

Am I eligible for the Epclusa patient assistance program?

You will need to meet the eligibility criteria for Epclusa assistance to be successfully enrolled in the patient assistance program. At NiceRx we review each Epclusa assistance program application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Epclusa patient assistance program? 

We do everything we can to make it as easy as possible to apply for the Epclusa patient assistance program. Our process is simple and straightforward, beginning with our enrollment application that you fill out online. It Is important to tell us about any medications you’re taking. 

This includes Epclusa as well as any vitamins, supplements, and medications you take. You will also need to provide us full details of your healthcare provider, insurance plan, and your household income. We need this information as it’s required by the pharmaceutical manufacturers who ship your medication.

Once NiceRx determines your potential eligibility for Epclusa assistance, we’ll handle the application process for you. We will help to enroll you in the Epclusa patient assistance program and request your Epclusa medication refills on your behalf for up to one year.

Is NiceRx an Epclusa coupons provider?

We are a service provider that helps eligible individuals access the Epclusa patient assistance program. NiceRx is not an Epclusa coupon, an Epclusa discount card, or an Epclusa copay card. We also don’t offer printable Epclusa manufacturer coupons, Epclusa discounts, rebates, Epclusa savings cards, trial offers, or free Epclusa samples.

Can NiceRx help me get Epclusa if I have insurance? 

We may still be able to help if you have insurance, but your insurance company won’t pay for your Epclusa medication. We may also be able to help if you have a high copay or coinsurance responsibility, if you don’t have insurance, or if your insurance plan doesn’t cover Epclusa. Apply online to find out more.

How much is Epclusa with insurance?

The cost of Epclusa will vary in accordance with your healthcare plan. To understand what you might have to pay with insurance contact your insurance provider or pharmacist. 

How much does Epclusa cost without insurance?

Epclusa prices without insurance will vary depending on your chosen retailer. As a guide, it can cost around $26,000 for a pack of 28, 400 mg-100 mg tablets. With NiceRx you’ll always pay a flat monthly fee of $49.

What is Epclusa?

Epclusa is a prescription medicine given to adults to treat hepatitis C. It’s usually prescribed to treat chronic (long-lasting) infections of the 1, 2, 3, 4, 5, or 6 virus genotypes (these are the different versions of the virus). Epclusa can be taken by itself to treat a hepatitis C infection, or with another medication called ribavirin. The medication is swallowed as a tablet. 

Hepatitis C is a disease caused by an infection of a hepatitis C virus. When you first get infected, you may have relatively mild symptoms, like a fever, dark urine, abdominal pain, and a yellow tinge to your skin. Some people have no symptoms at all. Hepatitis C is usually spread through blood, such as by sharing needles for drug use or using poorly sterilized medical equipment.

A small proportion of people clear the virus from their body, but in 75% to 85% of infected people, the virus lives on in the liver. At first you may feel no symptoms, but over time the infection can cause damage (liver disease) and reduce your liver function (cirrhosis). This could lead to liver failure and liver cancer. Although chronic hepatitis C infections can last for a long time, your body can overcome the infection, particularly with mediations like Epclusa. Epclusa stops the virus from being able to copy itself and spread through your cells, giving your body a better chance to kill it.

More information on what is Epclusa and Epclusa dosage

Epclusa active ingredients

Epclusa has two active ingredients in one tablet, called sofosbuvir and velpatasvir. They both work by stopping the hepatitis C virus from producing proteins it needs to copy itself. Viruses harm you by copying themselves (replication) and spreading through your body. To replicate themselves, they need to produce proteins that help them copy their DNA. But sofosbuvir and velpatasvir stops the hepatitis C virus from being able to produce two of these proteins. This slows how fast the virus replicates and spreads, and helps your immune system to overcome the infection.

Epclusa side effects & Epclusa drug interactions

The most common side effects caused by Epclusa include:

  • Headaches
  • Tiredness
  • Rashes

In rare instances, Epclusa can cause more serious side effects, including:

  • Severe allergic reactions to the medication
  • Reactivating a hepatitis B infection – if you’ve previously had hepatitis B, Epclusa could reactivate the virus, potentially causing serious liver problems, including liver failure and death
  • Slow heart rate (bradycardia) when taken with a medicine including amiodarone

In some instances, Epclusa can interact with other medications impacting how Epclusa and the other medications work. Some side effects can become more likely. It is known to interact with:

  • Rifapentine or rifabutin, antibiotics used to treat infections
  • Oxcarbazepine, carbamazepine, phenobarbital, used to treat epilepsy
  • St. John’s wort (an herbal medicine used to treat depression)
  • Any medications containing amiodarone, like Cordarone, Nexterone, or Pacerone, used to treat an irregular heartbeat
  • Any medications containing tenofovir disoproxil fumarate, used to treat HIV/AIDS
  • Efavirenz, used to treat HIV/AIDS
  • Digoxin, used to treat heart conditions
  • Dabigatran, used to thin the blood
  • Modafinil, used to treat sleep disorders
  • Statins, used to treat high cholesterol

Epclusa warnings & precautions

Epclusa isn’t suitable for everyone. Don’t take Epclusa if you:

  • Are allergic to the active ingredients sofosbuvir or velpatasvir
  • Are allergic to any of the other ingredients in Epclusa
  • Are under 18 years of age

Talk to your doctor before taking Epclusa if you:

  • Are taking any of the medications that could interact with Epclusa (see the section above)
  • Have ever had hepatitis B
  • Have liver problems other than hepatitis C infection
  • Have ever had a liver transplant
  • Have severe kidney problems or are on dialysis
  • Have an HIV infection
  • Are pregnant or are planning to get pregnant
  • Are breastfeeding or are planning to breastfeed

Related medication

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.