Jakafi Coupon & Prices

Is your Jakafi medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Jakafi medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Jakafi cost savings if eligible

If you are eligible for the Jakafi patient assistance program, the cost of your medication will be free. We only charge $49 a month, per medication, to cover our service fees. You could receive your Jakafi prescription for just $49 a month, regardless of the retail price of your medication.

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
5mg 10 tablets$2,300.00$49.00$2,251.00
10mg 30 tablets$6,900.00$49.00$6,851.00
15mg 30 tablets$6,900.00$49.00$6,851.00
20mg 30 tablets$6,900.00$49.00$6,851.00
25mg 30 tablets$6,900.00$49.00$6,851.00

Am I eligible for the Jakafi patient assistance program?

We will review your application to determine whether you are eligible for the Jakafi patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Jakafi patient assistance program?

We make it as easy as possible to apply for the Jakafi patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Jakafi. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Jakafi assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Jakafi patient assistance program, and we will automatically request your Jakafi medication refills for up to 1 year.

Is NiceRx a Jakafi coupon provider?

We are a service provider that helps eligible individuals access the Jakafi patient assistance program. That means that we do not offer printable Jakafi manufacturer coupons, Jakafi discounts, or free Jakafi samples. We are not a Jakafi coupon provider or Jakafi discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Jakafi if I have insurance?

We may be able to help you to access Jakafi patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Jakafi medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much is Jakafi with insurance?

The cost of Jakafi with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

How much does Jakafi cost without insurance?

Jakafi prices without insurance will vary depending on where you buy it and how much you buy. As a guide, Jakafi tablets 5 mg usually cost $15,400 for 60 tablets. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

What is Jakafi?

Jakafi contains the prescription medication ruxolitinib. Ruxolitinib blocks the action of certain enzymes in your body, these enzymes are known as janus associated kinases (JAKs).

Jakafi is used for the treatment of:

  • Certain types of myelofibrosis in adults, a condition where normal bone marrow is replaced by scar tissue.
  • Polycythemia vera, a condition where your bone marrow produces too many red blood cells in adults. It is prescribed when a medication called hydroxyurea has already been taken but it didn’t work well enough or its side effects could not be tolerated.  
  • Acute graft-versus-host disease (GVHD) in adults and children over 12 years old, who have already taken corticosteroids, but found it didn’t work well enough. 

Jakafi comes as an oral tablet. How many tablets you take and how often will be decided upon by your doctor based on your condition and medical history. Jakafi is usually given after other treatments have failed.

More information on what is Jakafi and Jakafi dosage

Jakafi active ingredients

The active ingredient in Jakafi is called ruxolitinib. When you take Jakafi, the ruxolitinib it contains attaches itself to a type of enzyme in your body called janus associated kinases (JAKs).

These enzymes are used by your immune system to cause inflammation. They play a role in causing or worsening your condition. Myelofibrosis and polycythemia vera are associated with mutations in genes that make these JAK enzymes. Your condition may be caused by your JAK enzymes not working properly. By binding with JAK enzymes, ruxolitinib turns them off, reducing the effect they have on your body. This can reduce any inflammation caused by your condition, helping to provide relief from your symptoms. 

Jakafi side effects

When Jakafi causes side effects, the most common include:

  • Headaches
  • Diarrhea
  • Dizziness
  • Fluid retention
  • An increased risk of mild infections
  • An increase in bruising

Other common, but potentially serious side effects include:

  • Low red blood cell counts that can cause anemia
  • Low blood platelet counts (thrombocytopenia) that can increase your risk of bleeding
  • Low white blood cell counts (neutropenia) that can weaken your immune system
  • An increased risk of serious infections

In rare instances, Jakafi can cause the following serious side effects:

  • Severe allergic reactions to the medication
  • An increased risk of developing non-melanoma skin cancers
  • An increase in blood cholesterol levels

Jakafi drug interactions

Jakafi can interact with other medications, including:

  • Any medications that can increase your risk of bleeding, including warfarin, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
  • Any medications taken to treat fungal infections, including ketoconazole, itraconazole, posaconazole, fluconazole, or voriconazole
  • Any antibiotics, including clarithromycin, telithromycin, ciprofloxacin, or erythromycin
  • Rifabutin or rifampicin, taken used to treat tuberculosis (TB)
  • Any medications taken to treat HIV/AIDS, like amprenavir, atazanavir, indinavir, lopinavir, ritonavir, nelfinavir, ritonavir, or saquinavir
  • Any anti-epilepsy medications taken to reduce seizures, like phenytoin, carbamazepine, or phenobarbital
  • Nefazodone, taken to treat depression
  • Mibefradil or diltiazem, taken to treat high blood pressure (hypertension) and chronic angina pectoris
  • Cimetidine, taken to treat heartburn
  • St. John’s wort, a herbal product taken to treat depression

Jakafi warnings & precautions

Do not take Jakafi if you:

  • Are allergic to the active ingredient ruxolitinib
  • Are allergic to any of the other ingredients in Jakafi 
  • Are under 18 years of age for myelofibrosis or polycythemia vera
  • Are under 12 years of age for acute graft-versus-host disease

Talk to your doctor before taking Jakafi if you:

  • Have a current infection
  • Have or have had hepatitis B
  • Have or have had tuberculosis, or have been in close contact with someone who has
  • Have or have had any liver problems
  • Have or have had any kidney problems or are on dialysis. If you are on dialysis, take your Jakafi after your dialysis
  • Have or have had skin cancer
  • Have high levels of fat in your blood, like cholesterol or triglycerides
  • Are pregnant or planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Related medications

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.