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Xgeva Patient assistance program

Is your Xgeva medication too expensive? Through NiceRx, you may be able to get Xgeva for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Xgeva medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Xgeva cost savings if eligible

If you are eligible for the Xgeva patient assistance program you can get your medication for free. Our monthly flat rate of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Xgeva through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Xgeva patient assistance program?

You could receive your Xgeva without paying the full retail price if you meet the eligibility criteria for assistance. This criteria is set by the pharmaceutical companies who are providing assistance programs. At NiceRx we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Xgeva patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Xgeva.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Xgeva patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Xgeva medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Xgeva coupons provider?

At NiceRx, we help eligible individuals access the Xgeva patient assistance program. This means that we are not a Xgeva coupon, a Xgeva discount card, or a Xgeva copay card provider. We do not offer any medication trial offers, or free Xgeva samples.

Can NiceRx help me get Xgeva if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Xgeva medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much is Xgeva with insurance?

The cost of Xgeva will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

How much does Xgeva cost without insurance?

Xgeva costs without insurance will vary by the retailer you buy it from. As a guide, Xgeva will typically cost around $3,400 for enough Xgeva for a monthly injection. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

What is Xgeva?

Xgeva is a prescription medication used to help prevent bone loss, bone breaks, and fractures. It is prescribed to:

  • Adults with a blood cancer called multiple myeloma
  • Adults with cancer that has spread to their bones and formed a solid tumor within the bone
  • Adults and children, aged 12 to 18 with a non-cancerous giant cell tumor of the bone
  • Adults with too much calcium in the blood (hypercalcemia)

Xgeva can help reduce bone loss, as well as the risk of bone breaks and fractures if you have one of the above conditions. Just like other parts of your body, bone is a living tissue that follows a growth cycle – old bone tissue is continually broken down and replaced with new bone cells. Xgeva alters the bone growth cycle by slowing how quickly old bone tissue is broken down and recycled, stopping too much bone from being lost. The medication is given as an injection under your skin (subcutaneous injection) of your stomach, upper thigh, or upper arm, typically once every four weeks.

Xgeva active ingredients

The active ingredient in Xgeva is called denosumab. It is a type of medicine called a human monoclonal antibody that has been designed to help reduce bone loss, by acting on specific cells in your body.

Denosumab works by regulating the activity of osteoclast cells in your body. Osteoclasts are a type of cell that breaks down and recycles bone tissue.

When you take Xgeva, the denosumab it contains blocks a substance in your body called RANKL, which normally acts on receptors called RANK on the surfaces of osteoclasts. This blocks the action of the osteoclast cells and slows how quickly your old bone is broken down, giving more time for new bone tissue to be produced and to grow properly.

Xgeva side effects

The most common side effects caused by Xgeva include:

  • Headaches
  • Back pain
  • Skin rashes
  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Constipation
  • Diarrhea
  • Loss of appetite
  • Fatigue

Sometimes Xgeva can cause more serious side effects. These can include:

  • Severe allergic reactions to the medication that can cause anaphylaxis
  • Shortness of breath (dyspnea)
  • A fall in red blood cells, called anemia
  • A severe jawbone problem (osteonecrosis) that can cause the bone to weaken and die
  • Swelling in the face, arms, hands, lower leg, and feet
  • Severe bone, joint, and muscle pain
  • An increased risk of thigh bone fractures
  • An increased risk of broken bones in the spine, especially if you have a history of risk factors such as osteoporosis or past fractures
  • Low levels of calcium in the blood (hypocalcemia)
  • High calcium levels in the blood (hypercalcemia)
  • Possible harm to your unborn baby

Your doctor will assess the benefits of taking Xgeva against your risk of side effects.

Xgeva drug interactions

Medications can interact with each other. This can change how the medications work and can make some side effects more likely. Tell your prescribing doctor about all drugs you are taking, particularly a medicine called Prolia (denosumab) as it contains the same active ingredient as Xgeva.

Xgeva also has major interactions with:

  • Cladribine – used to prevent the growth of cancer cells
  • Etelcalcetide – used to reduce parathyroid hormone in the body, but has a side effect of hypocalcemia

This list is not exhaustive and other drugs may interact with Xgeva.

Xgeva warning and precautions

Xgeva can cause harm to your unborn baby. Do not take Xgeva if you are pregnant and avoid becoming pregnant whilst taking it. Talk to your doctor about effective contraception. Tell your doctor right away if you are or suspect you are pregnant.

Xgeva is not suitable for everyone. Do not take Xgeva if you:

  • Are allergic to the active ingredient denosumab
  • Are allergic to any of the other ingredients in Xgeva
  • Are pregnant or are planning to become pregnant
  • Have low levels of calcium in your blood (hypocalcemia)

Talk to your doctor before taking Xgeva if you:

  • Take a medicine called Prolia (denosumab)
  • Have kidney disease or receive dialysis
  • Have or have ever had any jawbone problems
  • Have cancer or are receiving chemotherapy, radiation, or steroids
  • Have a blood clotting disorder such as anemia (low red blood cells)
  • Plan to have a tooth removed or any other form of dental surgery
  • Are breastfeeding or are planning to breastfeed

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.