Home / Medications / Zeposia

Zeposia Patient assistance program

Is your Zeposia medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Zeposia medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
    (00:38)
  • Uploading documents and billing
    (00:50)
  • SSN & billing information
    (00:33)
  • Medication delivery time
    (00:41)

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Zeposia cost savings if eligible

If you are eligible to receive your Zeposia prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Zeposia patient assistance?

To be eligible for the Zeposia patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Zeposia enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Zeposia patient assistance program?

Applying for the Zeposia patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Zeposia, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Zeposia assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Zeposia patient assistance program, we will also request your Zeposia medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Zeposia coupons provider?

NiceRx does not provide Zeposia coupons, discount cards, or copay cards. We do not offer printable Zeposia manufacturer coupons, Zeposia discounts, rebates, Zeposia savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Zeposia medication with NiceRx.

Can NiceRx help me get Zeposia if I have insurance?

NiceRx may be able to help you access Zeposia patient assistance if:

  • You have a high copay or coinsurance responsibility for Zeposia
  • Your insurance company will not pay for your Zeposia prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Zeposia cost without insurance?

Zeposia prices without insurance will vary by retailer. As a guide, Zeposia oral capsules (0.23 mg-0.46 mg) will typically cost around $1,800 for 7 capsules.

How much does Zeposia cost with insurance?

Your individual healthcare plan will determine the copay of Zeposia with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Zeposia?

Zeposia is an FDA (Food and Drug Administration)-approved medication manufactured by Bristol-Myers Squibb. It is classed as a sphingosine 1-phosphate receptor modulator for the treatment of relapsing forms of multiple sclerosis (RRMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Zeposia is also FDA-approved to treat moderate to severe active ulcerative colitis (UC) in adults. It is not known if Zeposia is safe and effective in children.

What doses of Zeposia are available?

Zeposia is available in capsule form, in the following doses: 0.23 mg, 0.46 mg, 0.92 mg.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Zeposia active ingredients

Ozanimod is a sphingosine 1-phosphate receptor modulator, which is thought to act by retaining lymphocytes in the lymph nodes, preventing those cells from crossing the blood-brain barrier into the central nervous system (CNS). Preventing the entry of these cells into the CNS reduces the number of relapses and may also prevent or delay disability.

Zeposia side effects

The most common side effects caused by Zeposia in clinical trials include:

  • Upper respiratory infections
  • Elevated liver enzymes
  • Low blood pressure when you stand up (orthostatic hypotension)
  • Painful and frequent urination (urinary tract infection)
  • Back pain
  • High blood pressure
  • Headache

In rare instances, Zeposia can cause more serious side effects. These can include:

  • Liver problems – unexplained nausea, vomiting, abdominal pain, feeling tired, yellow color to eyes or skin, dark urine, loss of appetite
  • A sudden severe increase in blood pressure can happen when you eat certain foods that contain high levels of tyramine
  • Problems breathing
  • Macular edema – a problem with your vision – your risk for macular edema is higher if you have diabetes or if you have had an inflammation of your eye called uveitis. Call your healthcare provider if you have symptoms such as blurriness or shadows in the center of your vision, sensitivity to light, or unusually colored vision
  • PRES (Posterior Reversible Encephalopathy Syndrome) – swelling or narrowing of blood vessels in your brain. Symptoms usually get better when you stop taking Zeposia, but if left untreated, it may lead to a stroke. Call your healthcare provider if you have symptoms such as a sudden severe headache, sudden confusion, sudden loss of vision, or other changes in your vision or seizure
  • Severe worsening of multiple sclerosis (MS) after stopping Zeposia

Your doctor will assess the benefits of using Zeposia against your risk of side effects. For more information, ask your healthcare professional or pharmacist or call your healthcare provider for medical advice about any side effects. You may report side effects to FDA at 1-800-FDA-1088.

Zeposia drug interactions

Zeposia can interact with other medications. These include:

  • Vaccines – avoid the use of live attenuated vaccines during and for up to 3 months after treatment
  • Strong CYP2C8 Inhibitors – gemfibrozil
  • CYP2C8 inducers such as rifampin
  • BCRP Inhibitors
  • Medicines that affect your immune system, such as alemtuzumab
  • Medicines to help control your heart rhythm
  • Opioids pain killers
  • Treatment for depression
  • Treatment for Parkinson’s disease
  • Medicines to control your heart rate and blood pressure

This list is not exhaustive and other drugs may interact with Zeposia.

Zeposia contraindications

You should not use Zeposia if you:

  • Are allergic to the active ingredient ozanimod
  • Are allergic to any of the other ingredients in Zeposia

Talk to your doctor before using Zeposia if you:

  • Are taking any of the medications that could interact with Zeposia
  • Are breastfeeding or are planning to breastfeed
  • Have a fever or active infection
  • Have a weakened immune system due to medicines or disease – you will have a higher risk of infections
  • Have had chickenpox or have received the vaccine for chickenpox. Your healthcare provider may do a blood test for chickenpox antibodies. You may have to get the full course of the vaccination for chickenpox (Varicella Zoster Virus) and then wait 1 month before you start taking Zeposia
  • Have a slow heart rate
  • Have arrhythmias (irregular heartbeat)
  • Have a history of a stroke
  • Have heart problems, including a heart attack or chest pain (unstable angina), or heart failure
  • Have high blood pressure (hypertension)
  • Have liver problems
  • Have breathing problems, including during your sleep (sleep apnea)
  • Have uveitis or any other eye problems
  • Have diabetes
  • Are pregnant or are planning to become pregnant – if you are a female who can become pregnant, you should use birth control during your treatment and for 3 months after
  • Are breastfeeding or plan to breastfeed

Zeposia generic

Zeposia is the trademark brand name for ozanimod manufactured by Bristol-Myers Squibb. A generic version of ozanimod is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Zeposia savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.